QQ客服 官方微博 反馈留言

浏览/检索结果: 共9条，第1-9条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of Cyclic Peptidomimetic Ligands Targeting the Extracellular Domain of EGFR 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 11219-11228 作者:  Zheng, Mengmeng;  Li, Chunpu;  Zhou, Mi;  Jia, Ru;  Cai, Gang 收藏  |  浏览/下载：66/0  |  提交时间：2021/11/04 Discovery of 2-(5-(quinolin-6-yl)-1,3,4-oxadiazol-2-yl)acetamide derivatives as novel PI3K alpha inhibitors via docking-based virtual screening 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 9 作者:  Gu, Dongyan;  Cheng, Gang;  Zhang, Mengmeng;  Zhou, Yu-Bo;  Li, Jia 收藏  |  浏览/下载：15/0  |  提交时间：2021/05/24 PI3K alpha inhibitors  Virtual screening  2-(5-(quinolin-6-yl)-1,3,4 oxadiazol-2-yl)acetamide  Molecular dynamics   Optimization of piperidine constructed peptidyl derivatives as proteasome inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 14 作者:  Zhao, Yanmei;  Xu, Lei;  Zhang, Jiankang;  Zhang, Mengmeng;  Lu, Jingyi 收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24 Proteasome inhibitor  Piperidine  Peptidyl  Anti-cancer  SAR   Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19 作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue 收藏  |  浏览/下载：22/0  |  提交时间：2020/12/21 Metabolic pathways  Isocitrate dehydrogenase 2  Conformational restriction  Macrocyclic derivatives  Inhibitors   Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19 作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue 收藏  |  浏览/下载：23/0  |  提交时间：2020/12/21 Metabolic pathways  Isocitrate dehydrogenase 2  Conformational restriction  Macrocyclic derivatives  Inhibitors   Discovery of Highly Polar beta-Homophenylalanine Derivatives as Nonsystemic Intestine-Targeted Dipeptidyl Peptidase IV Inhibitors 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 23, 页码: 10919-10925 作者:  Huang, Fubao;  Ning, Mengmeng;  Wang, Kai;  Liu, Jia;  Guan, Wenbo 收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01 3-(7-Azaindolyl)-4-indolylmaleimides as a novel class of mutant isocitrate dehydrogenase-1 inhibitors: Design, synthesis, and biological evaluation 期刊论文 ARCHIV DER PHARMAZIE, 2018, 卷号: 351, 期号: 10 作者:  Hu, Yuanyuan;  Gao, Anhui;  Liao, Honghui;  Zhang, Mengmeng;  Xu, Gaoya 收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 2-hydroxyglutaric acid  3-(7-azaindoyl)-4-indolylmaleimides  isocitrate dehydrogenase 1 inhibitors  tumor   Design, Synthesis and Biological Evaluation of Peptidyl Epoxyketone Proteasome Inhibitors Composed of beta-amino Acids 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2014, 卷号: 84, 期号: 5, 页码: 497-504 作者:  Zhang, Jiankang;  Han, Mengmeng;  Ma, Xiaodong;  Xu, Lei;  Cao, Jiayi 收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 anti-cancer  di- and tripeptides  epoxyketone  proteasome inhibitors  -amino acid   4-Benzofuranyloxynicotinamide derivatives are novel potent and orally available TGR5 agonists 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 82, 页码: 1-15 作者:  Zou, Qingan;  Duan, Hongliang;  Ning, Mengmeng;  Liu, Jia;  Feng, Ying 收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 TGR5  4-Benzofuranyloxynicotinamide  Gallbladder toxicity  Caco-2 permeability