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科研机构
上海药物研究所 [6]
西安交通大学 [2]
新疆理化技术研究所 [1]
内容类型
期刊论文 [9]
发表日期
2021 [4]
2020 [2]
2018 [1]
2014 [2]
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Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity
期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 187, 页码: 7
作者:
Kamoldinov, Khamidulla
;
Li, Jun
;
Eshbakova, Komila
;
Sagdullaev, Shamansur
;
Xu, Gaoya
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2021/08/17
Ferula samarkandica Korovin
Apiaceae
Samarcandicins A-I
Sesquiterpene coumarin
Cytotoxity
MV-4-11 cell
Mino cell
Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia
期刊论文
CHEMMEDCHEM, 2021, 页码: 12
作者:
Jin, Tingting
;
Wang, Peipei
;
Long, Xiubing
;
Jiang, Kailong
;
Song, Pinrao
收藏
  |  
浏览/下载:133/0
  |  
提交时间:2021/05/24
CHK1 inhibitor
diaminopyrimidine
DNA damage response
oral bioavailability
Design, synthesis and biological evaluation of thioether-containing lenalidomide and pomalidomide derivatives with anti-multiple myeloma activity
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 13
作者:
Wang, Yuhong
;
Mi, Tian
;
Li, Yiming
;
Kan, Weijuan
;
Xu, Gaoya
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Lenalidomide
Multiple myeloma
MM.1S
Late-stage sulfuration
Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity
期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 187, 期号: 7, 页码: 1-7
作者:
Kamoldinov, K (Kamoldinov, Khamidulla) 1 , 2
;
Li, J (Li, Jun) 1 , 2
;
Eshbakova, K (Eshbakova, Komila) 3
;
Sagdullaev, S (Sagdullaev, Shamansur) 3
;
Xu, GY (Xu, Gaoya) 4
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/07/27
Ferula samarkandica KorovinApiaceaeSamarcandicins A-ISesquiterpene coumarinCytotoxityMV-4-11 cellMino cell
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
;
Qu, Bingxue
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
;
Qu, Bingxue
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors
3-(7-Azaindolyl)-4-indolylmaleimides as a novel class of mutant isocitrate dehydrogenase-1 inhibitors: Design, synthesis, and biological evaluation
期刊论文
ARCHIV DER PHARMAZIE, 2018, 卷号: 351, 期号: 10
作者:
Hu, Yuanyuan
;
Gao, Anhui
;
Liao, Honghui
;
Zhang, Mengmeng
;
Xu, Gaoya
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
2-hydroxyglutaric acid
3-(7-azaindoyl)-4-indolylmaleimides
isocitrate dehydrogenase 1 inhibitors
tumor
Sulfatase 1 (hSulf-1) reverses basic fibroblast growth factor-stimulated signaling and inhibits growth of hepatocellular carcinoma in animal model.
期刊论文
Oncotarget, 2014, 卷号: 5, 期号: [db:dc_citation_issue], 页码: 5029-39
作者:
Xu Gaoya
;
Ji Weidan
;
Su Yinghan
;
Xu Yang
;
Yan Yan
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/02
Sulfatase 1 (hSulf-1) reverses basic fibroblast growth factor-stimulated signaling and inhibits growth of hepatocellular carcinoma in animal model
期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: [db:dc_citation_issue], 页码: 5029-5039
作者:
Xu, Gaoya
;
Ji, Weidan
;
Su, Yinghan
;
Xu, Yang
;
Yan, Yan
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/03
AKT/ERK signaling
apoptosis
cell cycle
human sulfatase 1
hepatocellular carcinoma
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