CORC

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CORC

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Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235
作者:  Qu, Bingxue;  Xu, Yongjin;  Lu, Yang;  Zhuang, Weihao;  Jin, Xinxin
收藏  |  浏览/下载：11/0  |  提交时间：2022/12/23
Discovery of 1,5-Dihydro-4H-imidazol-4-one Derivatives as Potent, Selective Antagonists of CXC Chemokine Receptor 2 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 5, 页码: 836-845
作者:  Che, Jinxin;  Wang, Zhilong;  Shen, Zheyuan;  Zhuang, Weihao;  Ying, Huazhou
收藏  |  浏览/下载：60/0  |  提交时间：2021/08/17
Isocitrate Dehydrogenase 2 Inhibitors for the Treatment of Hematologic Malignancies: Advances and Future Opportunities 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21
作者:  Huang, Feng;  Tian, Tian;  Wu, Yizhe;  Che, Jinxin;  Yang, Haiyan
收藏  |  浏览/下载：17/0  |  提交时间：2021/06/15
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue
收藏  |  浏览/下载：20/0  |  提交时间：2020/12/21
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue
收藏  |  浏览/下载：21/0  |  提交时间：2020/12/21
fDiscovery of pyrazole-thiophene derivatives as highly Potent, orally active Akt inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 72-85
作者:  Zhan, Wenhu;  Che, Jinxin;  Xu, Lei;  Wu, Yizhe;  Hu, Xiaobei
收藏  |  浏览/下载：15/0  |  提交时间：2020/07/01
Discovery of 3,4,6-Trisubstituted Piperidine Derivatives as Orally Active, Low hERG Blocking Akt Inhibitors via Conformational Restriction and Structure-Based Design 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 15, 页码: 7264-7288
作者:  Dong, Xiaowu;  Zhan, Wenhu;  Zhao, Mengting;  Che, Jinxin;  Dai, Xiaoyang
收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01
Discovery of novel indoleaminopyrimidine NIK inhibitors based on molecular docking-based support vector regression (SVR) model 期刊论文
CHEMICAL PHYSICS LETTERS, 2019, 卷号: 718, 页码: 38-45
作者:  Ye, Qing;  Li, Qiu;  Gao, Anhui;  Ying, Huazhou;  Cheng, Gang
收藏  |  浏览/下载：6/0  |  提交时间：2020/07/01
Discovery of Novel Indoleaminopyrimidine NIK Inhibitors based on Molecular Docking-based Support Vector Regression Model 期刊论文
Chemical Physics Letters, 2019
作者:  Qing Ye;  Qiu Li;  Anhui Gao;  Huazhou Ying;  Gang Cheng
收藏  |  浏览/下载：19/0  |  提交时间：2019/12/13
Ligand-based pharmacophore model for the discovery of novel CXCR2 antagonists as anti-cancer metastatic agents 期刊论文
ROYAL SOCIETY OPEN SCIENCE, 2018, 卷号: 5, 期号: 7
作者:  Che, Jinxin;  Wang, Zhilong;  Sheng, Haichao;  Huang, Feng;  Dong, Xiaowu
收藏  |  浏览/下载：41/0  |  提交时间：2019/01/08

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