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Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors 期刊论文
PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664
作者:  Xu, Jianghong;  Hu, Yuanyuan;  Liu, Xiaoqi;  Gao, Anhui;  Gao, Lixin
收藏  |  浏览/下载:34/0  |  提交时间:2021/12/01
Inhibition of B-cell receptor signaling disrupts cell adhesion in mantle cell lymphoma via RAC2 期刊论文
BLOOD ADVANCES, 2021, 卷号: 5, 期号: 1, 页码: 185-197
作者:  Wu, Wenjun;  Wang, Weige;  Franzen, Carrie A.;  Guo, Hui;  Lee, Jimmy
收藏  |  浏览/下载:40/0  |  提交时间:2020/07/01
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue
收藏  |  浏览/下载:20/0  |  提交时间:2020/12/21
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue
收藏  |  浏览/下载:21/0  |  提交时间:2020/12/21
Method for obtaining junction temperature of power semiconductor devices combining computational fluid dynamics and thermal network 期刊论文
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2020, 卷号: 976, 页码: 10
作者:  Peng, Lisha;  Shen, Wanzeng;  Feng, Anhui;  Liu, Yan;  Gao, Daqing
收藏  |  浏览/下载:29/0  |  提交时间:2021/12/09
Mitochondrial Uncoupling Coordinated With PDH Activation Safely Ameliorates Hyperglycemia via Promoting Glucose Oxidation 期刊论文
DIABETES, 2019, 卷号: 68, 期号: 12, 页码: 2197-2209
作者:  Jiang, Haowen;  Jin, Jia;  Duan, Yanan;  Xie, Zhifu;  Li, Yufeng
收藏  |  浏览/下载:24/0  |  提交时间:2020/07/01
Selective Late-Stage Oxygenation of Sulfides with Ground-State Oxygen by Uranyl Photocatalysis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 页码: 9
作者:  Li, Yiming;  Rizvi, S. Aal-e-Ali;  Hu, Deqing;  Sun, Danwen;  Gao, Anhui
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/01
Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino) pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 173, 页码: 44-62
作者:  Tong, Lexian;  Song, Pinrao;  Jiang, Kailong;  Xu, Lei;  Jin, Tingting
收藏  |  浏览/下载:19/0  |  提交时间:2020/07/01
Discovery of novel indoleaminopyrimidine NIK inhibitors based on molecular docking-based support vector regression (SVR) model 期刊论文
CHEMICAL PHYSICS LETTERS, 2019, 卷号: 718, 页码: 38-45
作者:  Ye, Qing;  Li, Qiu;  Gao, Anhui;  Ying, Huazhou;  Cheng, Gang
收藏  |  浏览/下载:6/0  |  提交时间:2020/07/01
Synthesis and biological evaluation of 3-aryl-4-indolyl-maleimides as potent mutant isocitrate dehydrogenase-1 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 4, 页码: 589-603
作者:  Liu, Xiaoqi;  Hu, Yuanyuan;  Gao, Anhui;  Xu, Meng;  Gao, Lixin
收藏  |  浏览/下载:28/0  |  提交时间:2020/07/01


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