Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity

doi:10.1016/j.phytochem.2021.112705

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	Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity
	Kamoldinov, K (Kamoldinov, Khamidulla) 1 , 2 ; Li, J (Li, Jun) 1 , 2 ; Eshbakova, K (Eshbakova, Komila) 3 ; Sagdullaev, S (Sagdullaev, Shamansur) 3 ; Xu, GY (Xu, Gaoya) 4 ; Zhou, YB (Zhou, Yubo) 4 ; Li, J (Li, Jia) 4 , 5 ; Aisa, HA (Aisa, Haji Akber) 1 , 2
刊名	PHYTOCHEMISTRY
	2021
卷号	187 期号:7 页码:1-7
关键词	Ferula samarkandica KorovinApiaceaeSamarcandicins A-ISesquiterpene coumarinCytotoxityMV-4-11 cellMino cell
DOI	10.1016/j.phytochem.2021.112705
英文摘要	Phytochemical study on the ethanolic extract of the dried roots of Ferula samarkandica Korovin led to the isolation of nine undiscribed sesquiterpene coumarins, samarcandicins A-I, along with thirteen known sesquiterpene coumarins. Their structures were characterized by detailed spectroscopic analysis including NMR and HR-ESI-MS. Mogoltacin and nevskin exhibited high inhibitory activity against MV-4-11 cell with IC50 values of 3.94 +/- 0.06 mu M and 3.87 +/- 0.10 mu M, respectively, and nevskin and feshurin showed high inhibitory activity against mino cell with IC50 values of 1.48 +/- 0.06 mu M and 7.88 +/- 0.60 mu M, respectively.
WOS记录号	WOS:000654130400001
内容类型	期刊论文
源URL	[http://ir.xjipc.cas.cn/handle/365002/7860]
专题	新疆理化技术研究所_资源化学研究室
通讯作者	Aisa, HA (Aisa, Haji Akber) 1 , 2
作者单位	1.Pilot Natl Lab Marine Sci & Technol Qingdao, Open Studio Druggabil Res Marine Nat Prod, 1 Wenhai Rd, Qingdao 266237, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 3.Acad Sci Uzbek, S Yu Yunusov Inst Chem Plant Subst, Prosp M Ulugbeka 83, Tashkent, Uzbekistan 4.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Zone, Beijing South Rd 40-1, Urumqi 830011, Peoples R China 5.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plant, Beijing South Rd 40-1, Urumqi 830011, Peoples R China
推荐引用方式 GB/T 7714	Kamoldinov, K ,Li, J ,Eshbakova, K ,et al. Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity[J]. PHYTOCHEMISTRY,2021,187(7):1-7.
APA	Kamoldinov, K .,Li, J .,Eshbakova, K .,Sagdullaev, S .,Xu, GY .,...&Aisa, HA .(2021).Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity.PHYTOCHEMISTRY,187(7),1-7.
MLA	Kamoldinov, K ,et al."Sesquiterpene coumarins from Ferula samarkandica Korovin and their bioactivity".PHYTOCHEMISTRY 187.7(2021):1-7.