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上海药物研究所 [14]
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An endoplasmic reticulum-associated degradation-related E2-E3 enzyme pair controls grain size and weight through the brassinosteroid signaling pathway in rice
期刊论文
PLANT CELL, 2023, 卷号: 35, 期号: 3, 页码: 1076-1091
作者:
Li, Jing
;
Zhang, Baolan
;
Duan, Penggen
;
Yan, Li
;
Yu, Haiyue
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/07
Global ubiquitinome analysis reveals the role of E3 ubiquitin ligase FaBRIZ in strawberry fruit ripening
期刊论文
JOURNAL OF EXPERIMENTAL BOTANY, 2023, 卷号: 74, 期号: 1, 页码: 214-232
作者:
Wang, Yuying
;
Kong, Lingxi
;
Wang, Weihao
;
Qin, Guozheng
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/07
Fruit ripening
protein post-translational modification
strawberry
ubiquitination
ubiquitinome
ubiquitin-proteasome system (UPS)
Development of a novel PROTAC using the nucleic acid aptamer as a targeting ligand for tumor selective degradation of nucleolin
期刊论文
MOLECULAR THERAPY-NUCLEIC ACIDS, 2022, 卷号: 30
作者:
Zhang, Lin
;
Li, Ling
;
Wang, Xia
;
Liu, Huimin
;
Zhang, Yibin
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  |  
浏览/下载:22/0
  |  
提交时间:2022/12/23
The contribution of proteasomal impairment to autophagy activation by C9orf72 poly-GA aggregates
期刊论文
CELLULAR AND MOLECULAR LIFE SCIENCES, 2022, 卷号: 79, 期号: 9
作者:
Pu, Mei
;
Tai, Yusi
;
Yuan, Luyang
;
Zhang, Yu
;
Guo, Huijie
收藏
  |  
浏览/下载:120/0
  |  
提交时间:2022/10/09
ALS
C9orf72
Poly-GA
Proteasome
Autophagy
Key Considerations in Targeted Protein Degradation Drug Discovery and Development
期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:
Qin, Liena
;
Dai, Han
;
Wang, Junfeng
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  |  
浏览/下载:16/0
  |  
提交时间:2022/12/23
targeted protein degradation
PROTAC
molecular glue
chemically induced proximity
drug discovery and development
Ubiquitin-proteasome pathway plays an essential regulatory role during spermatangium formation in Neopyropia yezoensis
期刊论文
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 2022, 卷号: 62, 页码: 12
作者:
Niu, Jianfeng
;
Yang, Jiali
;
Feng, Jianhua
;
Feng, Zezhong
;
Wang, Xia
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/07/18
Neopyropia yezoensis
Ubiquitin
26S proteasome
Sexual differentiation
Spermatangium
Molecular mechanism
The CDC48 complex mediates ubiquitin-dependent degradation of intra-chloroplast proteins in plants
期刊论文
CELL REPORTS, 2022, 卷号: 39, 期号: 2
作者:
Li, Jialong
;
Yuan, Jiarui
;
Li, Yuhong
;
Sun, Huilun
;
Ma, Tingting
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/07
PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy
期刊论文
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12
作者:
Qi, Si-Min
;
Dong, Jinyun
;
Xu, Zhi-Yuan
;
Cheng, Xiang-Dong
;
Zhang, Wei-Dong
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/06/15
PROTAC
E3 ubiquitin ligase
protein degradation
ubiquitin-proteasome system
cancer therapy
Targeting Protein Neddylation to Inactivate Cullin-RING Ligases by Gossypol: A Lucky Hit or a New Start?
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15
作者:
Yu, Qing
;
Sun, Yi
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/03/15
anti-cancer drug
cullin-RING E3 ligases
natural product
high-throughput screen
neddylation
small-molecule inhibitors
Pol-miR-363-3p plays a significant role in the immune defense of Japanese flounder Paralichthys olivaceus against bacterial and viral infection
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2020, 卷号: 104, 页码: 439-446
作者:
Sun, Yan-Ling
;
Guan, Xiao-Lu
;
Zhang, Peng
;
Li, Mo-Fei
;
Zhang, Jian
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/10/26
Paralichthys olivaceus
miRNA
Ubiquitin-specific protease
Pathogen
Infection
Immunity
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