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Bexarotent attenuated CCI-induced spinal neuroinflammation and neuropathic pain by targeting MKP-1. 期刊论文
The journal of pain : official journal of the American Pain Society, 2019
作者:  Gui, Yulong;  Duan, Shunyuan;  Xiao, Lihong;  Tang, Jing;  Li, Aiyuan*
收藏  |  浏览/下载:20/0  |  提交时间:2019/12/27
Broad targeting of triptolide to resistance and sensitization for cancer therapy 期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:  Hou, Zhen-yan;  Tong, Xiao-pei;  Peng, Yong-bo;  Zhang, Bi-Kui*;  Yan, Miao*
收藏  |  浏览/下载:48/0  |  提交时间:2019/12/03
ABC  ATP-binding cassette  AKT  V-Akt murine thymoma viral oncogene homolog  ALDH1  aldehyde dehydrogenase 1  AR  androgen receptor  Bad  Bcl-2-associated death promoter  Bak  Bcl-2 homologous antagonist killer  Bax  Bcl-2-associated X protein  Bcl-2  B-cell lymphoma  Bcl-xL  Bcl-extra large  Bcl-xs  Bcl-extra short  BCRP  breast cancer resistance protein  Bid  BH3 interacting domain death agonist  Bik  Bcl-2-interacting killer  BNIP3  Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3  CAF  cancer-associated fibroblast  CAIX  carbonic anhydrase IX  cFLIP  cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein  ChIP  chromatin immunoprecipitation  CI  Combination Index  cIAP1/2  cellular IAP1/2  CML  chronic myelogenous leukemia  CSC  cancer stem cell  DISC  death-inducing signaling complex  DR  death receptor  DRI  Dose Reduction Index  ECM  extracellular matrix  EMT  epithelial-mesenchymal transition  EpCAM  epithelial cell adhesion molecule  GLUT  glucose transporter  GSK3β  glycogen synthase kinase-3β  HIF-1  hypoxia inducible factor-1  HSF1  heat shock factor 1  HSP  heat shock protein  IAP  inhibitor of apoptosis protein  JNK  c-JUN N-terminal kinase  MAPK  mitogen-activated protein kinase  Mcl-1  myeloid leukemia cell differentiation protein  MDM2  murine double minute 2  MDR  multidrug resistance  MKP  MAPK phosphatase  MRP1  multidrug resistance protein 1  NF-κB  nuclear factor-kappaB  pAkt  phosphor-Akt  PARP  poly ADP-ribose polymerase  P-gp  P-glycoprotein  PI3K-PTEN  phosphatidylinositol 3-kinase-phosphatase and tensin homolog  PKC  phosphorylated at Ser9 by protein kinase C  pp2A  protein phosphatase 2A  REST  repressor element-1 silencing transcription factor  SAR  structure-activity relationship  TAM  tumor-associated macrophage  TFIIH  transcription factor IIH  TKI  tyrosine kinase inhibitor  TM  tumor-microenvironment  TRAIL/Apo-2L  TNF-related apoptosis-inducing ligand  tRXRα  the N-terminal truncated form of the nuclear retinoid X receptor-α  TWHF  Tripterygium wilfordii Hook F  VEGF  vascular endothelial growth factor  XIAP  X-linked IAP  XPB  xerodermapigmentosum group B protein  Triptolide  Antineoplastic  Resistance  Sensitization  Mechanism  
Obacunone causes sustained expression of MKP-1 thus inactivating p38 MAPK to suppress pro-inflammatory mediators through intracellular MIF 期刊论文
2018, 卷号: 119, 期号: 1, 页码: 837-849
作者:  Gao, Yuan;  Hou, Rui;  Liu, Fen;  Liu, Haibo;  Fei, Qiaoling
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/03
丝裂原活化蛋白激酶磷酸酶1(MKP-1)去泛素化酶的筛选及验证 学位论文
北京: 中国科学院大学, 2017
作者:  杨光玺
收藏  |  浏览/下载:45/0  |  提交时间:2019/09/24
Triptolide reduces the viability of osteosarcoma cells by reducing MKP-1 and Hsp70 expression 期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2016, 卷号: 11, 期号: 5, 页码: 2005-2010
作者:  Zhao, Lei;  Jiang, Bo;  Wang, Dong;  Liu, Wei;  Zhang, Huawu
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/16
S-Nitrosylation of mitogen activated protein kinase phosphatase-1 suppresses radiation-induced apoptosis 期刊论文
CANCER LETTERS, 2012, 卷号: 314, 期号: [db:dc_citation_issue], 页码: 137-146
作者:  Guan, Weiping;  Sha, Jibin;  Chen, Xiaojuan;  Xing, Yaling;  Yan, Jinqi
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/10
Probucol mediates vascular remodeling after percutaneous transluminal angioplasty via down-regulation of the ERK1/2 signaling pathway 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2007, 卷号: 570, 期号: 1-3, 页码: 125-134
作者:  Yang, Yun-Bo;  Yang, Yi-Xin;  Su, Bo;  Tang, Yun-Lian;  Zhu, Bing-Yang
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
Feedback control of mkp-1 expression by p38 期刊论文
Cellular signalling, 2007, 卷号: 19, 期号: 2, 页码: 393-400
作者:  Hu, Jun-Hao;  Chen, Ting;  Zhuang, Zi-Heng;  Kong, Ling;  Yu, Ming-Can
收藏  |  浏览/下载:14/0  |  提交时间:2019/05/10
Calcineurin enhances MAPK phosphatase-1 expression and p38 MAPK inactivation in cardiac myocytes 期刊论文
2001
Lim, H. W.; New, L.; Han, J. H.; Molkentin, J. D.; 韩家淮
收藏  |  浏览/下载:5/0  |  提交时间:2013/12/12


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