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山东大学 [9]
武汉大学 [7]
复旦大学上海医学院 [4]
昆明医科大学 [2]
厦门大学 [1]
四川大学 [1]
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期刊论文 [20]
学位论文 [8]
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Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
ShDcR3 sensitizes TRAIL-resistant HCC cells by inducing caspase-dependent apoptosis while suppressing NF-kappa B dependent cFLIP(L) expression
期刊论文
PLOS ONE, 2018, 卷号: 13, 期号: 2
作者:
Liang, Dong-Yu
;
Huang, Wei
;
Chang, Qing
;
Hou, Yan-Qiang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/06
Plumbagin enhances TRAIL-induced apoptosis of human leukemic Kasumi-1 cells through upregulation of TRAIL death receptor expression, activation of caspase-8 and inhibition of cFLIP
期刊论文
ONCOLOGY REPORTS, 2017, 卷号: 37, 期号: 6
作者:
Xie, Yinghua
;
Kong, Xiaoyang
;
Luo, Jing
;
Xu, Tongpeng
;
Zhou, Yunjiao
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
plumbagin
tumor necrosis factor-alpha-related apoptosis-inducing ligand
death receptor
t(8
21)
reactive oxygen species
xenograft
Icariside II overcomes TRAIL resistance of melanoma cells through ROS-mediated downregulation of STAT3/cFLIP signaling
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 32
作者:
Tse, Anfernee Kai-Wing
;
Wu, Jinfeng
;
Du, Juan
;
Fu, Xiuqiong
;
Yu, Zhi-Ling
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
melanoma
TRAIL
icariside II
pSTAT3
ROS
Effects of histone deacetylase inhibitor trichostatin A combined with cisplatin on apoptosis of A549 cell line
期刊论文
Thoracic cancer., 2015, 卷号: 6, 期号: 2, 页码: 202-208
作者:
Zhang, Xuan
;
Jiang, Shu-Juan
;
Shang, Bin
;
Jiang, Hong-Juan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/17
Caspase-8
cellular Fas-associated death domain-like interleulin-1 converting enzyme inhibitory protein (cFLIP)
cisplatin
Trichostatin A (TSA)
Wogonin enhances antitumor activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo through ROS-mediated downregulation of cFLIP(L) and IAP proteins
期刊论文
2013, 卷号: 18, 期号: 5, 页码: 618-626
作者:
Yang, Lan[1,2]
;
Wang, Qiong[1]
;
Li, Daoxia[1]
;
Zhou, Yuqiong[1]
;
Zheng, Xuelian[1]
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/06
cFLIP对心肌肥厚发生发展的作用研究
学位论文
2012
作者:
王纯奕
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  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
心血管病学
cFLIP
基因敲除
转基因
心肌肥厚
cFLIP在压力超负荷诱导的心肌肥厚及纤维化中的作用
期刊论文
中国心脏起搏与心电生理杂志, 2012, 期号: 2
作者:
王纯奕
;
范阳
;
汪心安
;
肖金凤
;
黎明江
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
心血管病学
cFLIP
基因敲除
心肌肥厚
纤维化
心功能
核因子-κB在滇南小耳猪胆道损伤修复模型中表达的研究
期刊论文
中国实用外科杂志, 2011, 卷号: 31, 期号: S1
作者:
胡平海
;
李立
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/04
细胞核因子(NF-κB)
caspase-8同源结构FLICE抑制蛋白(cFLIP)
胆管成纤维细胞
Triggering of death receptor apoptotic signaling by human papillomavirus 16 E2 protein in cervical cancer cell lines is mediated by interaction with c-FLIP
期刊论文
2011
方亚
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  |  
浏览/下载:2/0
  |  
提交时间:2013/12/12
HPV E2
Apoptosis
cFLIP
Death receptor signaling
Cervical carcinogenesis
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