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Broad targeting of triptolide to resistance and sensitization for cancer therapy 期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:  Hou, Zhen-yan;  Tong, Xiao-pei;  Peng, Yong-bo;  Zhang, Bi-Kui*;  Yan, Miao*
收藏  |  浏览/下载:48/0  |  提交时间:2019/12/03
ABC  ATP-binding cassette  AKT  V-Akt murine thymoma viral oncogene homolog  ALDH1  aldehyde dehydrogenase 1  AR  androgen receptor  Bad  Bcl-2-associated death promoter  Bak  Bcl-2 homologous antagonist killer  Bax  Bcl-2-associated X protein  Bcl-2  B-cell lymphoma  Bcl-xL  Bcl-extra large  Bcl-xs  Bcl-extra short  BCRP  breast cancer resistance protein  Bid  BH3 interacting domain death agonist  Bik  Bcl-2-interacting killer  BNIP3  Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3  CAF  cancer-associated fibroblast  CAIX  carbonic anhydrase IX  cFLIP  cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein  ChIP  chromatin immunoprecipitation  CI  Combination Index  cIAP1/2  cellular IAP1/2  CML  chronic myelogenous leukemia  CSC  cancer stem cell  DISC  death-inducing signaling complex  DR  death receptor  DRI  Dose Reduction Index  ECM  extracellular matrix  EMT  epithelial-mesenchymal transition  EpCAM  epithelial cell adhesion molecule  GLUT  glucose transporter  GSK3β  glycogen synthase kinase-3β  HIF-1  hypoxia inducible factor-1  HSF1  heat shock factor 1  HSP  heat shock protein  IAP  inhibitor of apoptosis protein  JNK  c-JUN N-terminal kinase  MAPK  mitogen-activated protein kinase  Mcl-1  myeloid leukemia cell differentiation protein  MDM2  murine double minute 2  MDR  multidrug resistance  MKP  MAPK phosphatase  MRP1  multidrug resistance protein 1  NF-κB  nuclear factor-kappaB  pAkt  phosphor-Akt  PARP  poly ADP-ribose polymerase  P-gp  P-glycoprotein  PI3K-PTEN  phosphatidylinositol 3-kinase-phosphatase and tensin homolog  PKC  phosphorylated at Ser9 by protein kinase C  pp2A  protein phosphatase 2A  REST  repressor element-1 silencing transcription factor  SAR  structure-activity relationship  TAM  tumor-associated macrophage  TFIIH  transcription factor IIH  TKI  tyrosine kinase inhibitor  TM  tumor-microenvironment  TRAIL/Apo-2L  TNF-related apoptosis-inducing ligand  tRXRα  the N-terminal truncated form of the nuclear retinoid X receptor-α  TWHF  Tripterygium wilfordii Hook F  VEGF  vascular endothelial growth factor  XIAP  X-linked IAP  XPB  xerodermapigmentosum group B protein  Triptolide  Antineoplastic  Resistance  Sensitization  Mechanism  
ShDcR3 sensitizes TRAIL-resistant HCC cells by inducing caspase-dependent apoptosis while suppressing NF-kappa B dependent cFLIP(L) expression 期刊论文
PLOS ONE, 2018, 卷号: 13, 期号: 2
作者:  Liang, Dong-Yu;  Huang, Wei;  Chang, Qing;  Hou, Yan-Qiang
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/06
Plumbagin enhances TRAIL-induced apoptosis of human leukemic Kasumi-1 cells through upregulation of TRAIL death receptor expression, activation of caspase-8 and inhibition of cFLIP 期刊论文
ONCOLOGY REPORTS, 2017, 卷号: 37, 期号: 6
作者:  Xie, Yinghua;  Kong, Xiaoyang;  Luo, Jing;  Xu, Tongpeng;  Zhou, Yunjiao
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/05
Icariside II overcomes TRAIL resistance of melanoma cells through ROS-mediated downregulation of STAT3/cFLIP signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 32
作者:  Tse, Anfernee Kai-Wing;  Wu, Jinfeng;  Du, Juan;  Fu, Xiuqiong;  Yu, Zhi-Ling
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/05
Effects of histone deacetylase inhibitor trichostatin A combined with cisplatin on apoptosis of A549 cell line 期刊论文
Thoracic cancer., 2015, 卷号: 6, 期号: 2, 页码: 202-208
作者:  Zhang, Xuan;  Jiang, Shu-Juan;  Shang, Bin;  Jiang, Hong-Juan
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/17
Wogonin enhances antitumor activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo through ROS-mediated downregulation of cFLIP(L) and IAP proteins 期刊论文
2013, 卷号: 18, 期号: 5, 页码: 618-626
作者:  Yang, Lan[1,2];  Wang, Qiong[1];  Li, Daoxia[1];  Zhou, Yuqiong[1];  Zheng, Xuelian[1]
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/06
cFLIP对心肌肥厚发生发展的作用研究 学位论文
2012
作者:  王纯奕
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/05
cFLIP在压力超负荷诱导的心肌肥厚及纤维化中的作用 期刊论文
中国心脏起搏与心电生理杂志, 2012, 期号: 2
作者:  王纯奕;  范阳;  汪心安;  肖金凤;  黎明江
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/05
核因子-κB在滇南小耳猪胆道损伤修复模型中表达的研究 期刊论文
中国实用外科杂志, 2011, 卷号: 31, 期号: S1
作者:  胡平海;  李立
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/04
Triggering of death receptor apoptotic signaling by human papillomavirus 16 E2 protein in cervical cancer cell lines is mediated by interaction with c-FLIP 期刊论文
2011
方亚
收藏  |  浏览/下载:2/0  |  提交时间:2013/12/12


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