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科研机构
南华大学 [2]
山东大学 [2]
中南大学 [2]
复旦大学上海医学院 [2]
西安交通大学 [1]
武汉大学 [1]
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期刊论文 [12]
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2017 [2]
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Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Co-expression of murine double minute 2 siRNA and wild-type p53 induces G(1) cell cycle arrest in H1299 cells
期刊论文
MOLECULAR MEDICINE REPORTS, 2017, 卷号: 16, 期号: 6
作者:
Liu, Long
;
Zhang, Ping
;
Guo, Hua
;
Tang, Xinyu
;
Liu, Lianqin
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
p53
murine double minute 2
p21
G(1) cell cycle arrest
co-expression
Alterations in expression levels of genes in p53-related pathways determined using RNA-Seq analysis in patients with breast cancer following CIK therapy
期刊论文
ONCOLOGY LETTERS, 2017, 卷号: 14, 期号: 6
作者:
Hu, Zuowei
;
Zhang, Xiaoye
;
Yang, Hang
;
Qin, Shuanglai
;
Liu, Yaqi
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
breast cancer
cytokine-induced killer therapy
p53
murine double minute 2 homolog
RNA sequencing
Renoprotective approaches and strategies in acute kidney injury
期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 163, 页码: 58-73
作者:
Yang, Yuan
;
Song, Meifang
;
Liu, Yu
;
Liu, Hong
;
Sun, Lin
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/03
ACTH
Adrenocorticotropic hormone
AIF
Apoptosis inducing factor
AKI
Acute kidney injury
BMSC
Bone marrow derived stem cells
CIN
Contrast-induced nephropathy
COMP-Ang1
Cartilage oligomeric matrix protein-angiopoietin-1
CysLT1R
Cysteinyl leukotriene-1 receptor
DMARD
Disease-modifying antirheumatic drugs
eNOS
Endothelial nitric oxide synthase
eEPCs
Endothelial progenitor cells
HDAC
Histone deacetylase
HSPC
Hematopoietic stem and progenitor cells
IRI
Ischemia–reperfusion injury
ICAM-1
Intercellular adhesion molecule-1
JNK
c-Jun N-terminal kinase
KIF3B
Kinesin family member 3B
KIM-1
Kidney injury molecule 1
MAPK
Mitogen-activated protein kinase
MCP-1
Monocyte chemotactic protein-1
α-MSH
Alpha-melanocyte-stimulating hormone
MFG-E8
Milk fat globule-epidermal growth factor-factor VIII
MPT
Mitochondrial permeability transition
MSCs
Mesenchymal stem cells
NGAL
Neutrophil gelatinase-associated lipocalin
MDM2
Murine double minute-2
MMP-2
Matrix metallopeptidase 2
mTOR
Mammalian target of rapamycin
PI3K
Phosphatidylinositol-3 kinase
PACAP
Pituitary adenylate cyclase activating polypeptide
RAAS
Renin–angiotensin–aldosterone system
RANTES
Regulated upon activation normal T-cell expressed and secreted
RIP1
Receptor-interacting protein 1
TNF-α
Tumor necrosis factor-alpha
TWEAK
TNF-like weak inducer of apoptosis
VDRA
Vitamin D receptor agonist
Acute kidney injury
Kidney protection
Kidney repair
Renoprotection
Ischemia–reperfusion
Nephrotoxicity
Adenovirus siMDM2 and NDRG2 Gene Therapy Inhibits Cell Proliferation and Induces Apoptosis of Squamous Cell Carcinoma
期刊论文
CELL BIOCHEMISTRY AND BIOPHYSICS, 2015, 卷号: 73, 期号: 2, 页码: 513-518
作者:
Wang, Shouzhong
;
Chen, Nan
;
Dong, Na
;
Lu, Leihong
;
Liu, Liqian
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/17
Squamous cell carcinoma
Murine double minute 2
Gene silencing
N-myc
downstream-regulated gene 2
Gene therapy
PI3K/Akt signaling in osteosarcoma
期刊论文
Clinica Chimica Acta, 2015, 卷号: 444, 期号: Volume 444, 页码: 182-192
作者:
Zhang, Jian
;
Yu, Xiao-Hua
;
Yan, Yi-Guo
;
Wang, Cheng
;
Wang, Wen-Jun*
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/27
OS
osteosarcoma
PI3K
phosphatidylinositol 3-kinase
PTEN
phosphatase and tensin homolog
mTOR
mammalian target of rapamycin
RTKs
receptor tyrosine kinases
PDGFR
platelet-derived growth factor receptor
IGF1R
insulin-like growth factor 1 receptor
PIP2
phosphatidylinositol 4,5-biphosphate
PIP3
phosphatidylinositol 3,4,5-triphosphate
PDK1
phosphoinositide-dependent kinase 1
PH
pleckstrin homology
CDK
cyclin-dependent kinase
NF-κB
nuclear factor-κB
MDM2
Murine double minute 2
Rb
retinoblastoma
CSCs
cancer stem cells
CXCR7
CXC chemokine receptor 7
GA
gallic acid
miRNAs
microRNAs
TNF
tumor necrosis factor
HIF-1
hypoxia-inducible factor-1
ET-1
endothelin-1
ETAR
endothelin A receptor
MMP
matrix metalloproteinase.
OS
PI3K
Akt
PTEN
mTOR
MicroRNAs in osteosarcoma
期刊论文
Clinica Chimica Acta, 2015, 卷号: 444, 页码: 9-17
作者:
Zhang, Jian
;
Yan, Yi-Guo
;
Wang, Cheng
;
Zhang, Shu-Jun
;
Yu, Xiao-Hua*
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/27
OS
osteosarcoma
miRNAs
microRNAs
CSCs
cancer stem cells
RNA pol
RNA polymerase
DGCR8
DiGeorge syndrome critical gene 8
RISC
RNA-induced silencing complex
Exp 5
exportin 5
Ago
argonaute
MREs
miRNA recognition elements
APE1
apurinic/apyrimidinic endonuclease 1
MDM
murine double minute
TP53
tumor suppressor p53
mTOR
mammalian target of rapamycin
Eag1
ether à go-go 1
PI3K
phosphatidylinositol-3-kinase
PTEN
phosphatase and tensin homolog deleted on chromosome ten
Hsp90B1
heat shock protein 90B1
BMP2
bone morphogenetic protein 2
IGF1R
insulin-like growth factor 1 receptor
FAK
phospho-Akt and focal adhesion kinase
LPAATβ
lysophosphatidic acid acyltransferase β
HMGB1
high-mobility group box 1
FASN
fatty acid synthase
LZTS1
leucine zipper putative tumor suppressor 1
MMP
matrix metalloproteinase
LNA
locked nucleic acid
DATS
diallyl trisulfide
miRNAs
OS
TP53
Notch
Chemoresistance
鼠双微粒体-2基因沉默对人肝癌HepG2细胞移植瘤生长的抑制作用
期刊论文
中华肝脏病杂志, 2013, 卷号: 21, 期号: 3
作者:
赵燕颖[1]李亚刚[1]孙远杰[1]刘海鹏[2]杨泽成[3]张舵舵[2]赵春燕[4]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
癌,肝细胞
基因沉默
RNA,小分子干扰
基因,p53
鼠双微粒体-2基因
Carcinoma,hepatocellular
Gene silencing
RNA,small interfering
Genes,p53
Murine double minute 2
Induction of p53 expression and apoptosis by a recombinant dual-target MDM2/MDMX inhibitory protein in wild-type p53 breast cancer cells
期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2013, 卷号: 43, 期号: [db:dc_citation_issue], 页码: 1935-1942
作者:
Geng, Qian-Qian
;
Dong, Dan-Feng
;
Chen, Nan-Zheng
;
Wu, Yin-Ying
;
Li, En-Xiao
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/10
murine double minute X
murine double minute 2
breast cancer
p53
Murine double minute 2 promoter SNP309 polymorphism and prostate cancer risk: A meta-analysis
期刊论文
INTERNATIONAL JOURNAL OF UROLOGY, 2012, 卷号: 19, 期号: 10
作者:
Liu, Guoyuan
;
Jiang, Deke
;
Shen, Suqin
;
Yu, Long
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/19
meta-analysis
murine double minute 2 SNP309
polymorphism
prostate cancer
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