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Pharmacokinetics, mass balance, and metabolism of [C-14]vicagrel, a novel irreversible P2Y(12) inhibitor in humans 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:  Zheng, Yuan-dong;  Zhang, Hua;  Zhan, Yan;  Bian, Yi-cong;  Ma, Sheng
收藏  |  浏览/下载:42/0  |  提交时间:2021/05/24
Update of P2Y receptor pharmacology: IUPHAR Review 27 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 11, 页码: 2413-2433
作者:  Jacobson, Kenneth A.;  Delicado, Esmerilda G.;  Gachet, Christian;  Kennedy, Charles;  von Kuegelgen, Ivar
收藏  |  浏览/下载:60/0  |  提交时间:2020/07/01
Optimization of P2Y(12) Antagonist Ethyl 6-(4-((Benzylsulfonyl)carbarnoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate (AZD1283) Led to the Discovery of an Oral Antiplatelet Agent with Improved Druglike Properties 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 3088-3106
作者:  Kong, Deyu;  Xue, Tao;  Guo, Bin;  Cheng, Jianjun;  Liu, Shunyin
收藏  |  浏览/下载:13/0  |  提交时间:2020/07/01
Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y(12) inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing 期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 127, 页码: 151-160
作者:  Li, Cai;  Zhang, Yifan;  Chen, Weili;  Lu, Youming;  Li, Wei
收藏  |  浏览/下载:102/0  |  提交时间:2019/01/08
Design, synthesis, and biological evaluation of 2-(phenoxyaryl)-3-urea derivatives as novel P2Y(1) receptor antagonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 302-310
作者:  Peng, Jingjing;  Zhao, Lifen;  Wang, Lanlan;  Chen, Hui;  Qiu, Yunguang
收藏  |  浏览/下载:46/0  |  提交时间:2019/01/08
3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 18, 页码: 8136-8154
作者:  Baqi, Younis;  Pillaiyar, Thanigaimalai;  Abdelrahman, Aliaa;  Kaufmann, Olesja;  Aishaibani, Samer
收藏  |  浏览/下载:105/0  |  提交时间:2019/01/08
Dynamic States of the Ligand-Free Class A G Protein-Coupled Receptor Extracellular Side 期刊论文
BIOCHEMISTRY, 2018, 卷号: 57, 期号: 32, 页码: 4767-4775
作者:  Zhang, Qiansen;  Zhou, Mang;  Zhao, Lifen;  Jiang, Hualiang;  Yang, Huaiyu
收藏  |  浏览/下载:24/0  |  提交时间:2019/01/08
Structural basis for signal recognition and transduction by platelet-activating-factor receptor 期刊论文
NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2018, 卷号: 25, 期号: 6, 页码: 488-+
作者:  Cao, Can;  Tan, Qiuxiang;  Xu, Chanjuan;  He, Lingli;  Yang, Linlin
收藏  |  浏览/下载:68/0  |  提交时间:2019/01/08
Chemical Diversity in the G Protein-Coupled Receptor Superfamily 期刊论文
TRENDS IN PHARMACOLOGICAL SCIENCES, 2018, 卷号: 39, 期号: 5, 页码: 494-512
作者:  Vass, Marton;  Kooistra, Albert J.;  Yang, Dehua;  Stevens, Raymond C.;  Wang, Ming-Wei
收藏  |  浏览/下载:39/0  |  提交时间:2019/01/08
Development and validation of a sensitive and rapid UHPLC-MS/MS method for the simultaneous quantification of the common active and inactive metabolites of vicagrel and clopidogrel in human plasma 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018, 卷号: 149, 页码: 394-402
作者:  Liu, Cai;  Lu, Youming;  Sun, Hongbin;  Yang, Jin;  Liu, Yongqiang
收藏  |  浏览/下载:32/0  |  提交时间:2019/01/08


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