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HPLC-MS-based untargeted metabolomic analysis of differential plasma metabolites and their associated metabolic pathways in reproductively anosmic black porgy, Acanthopagrus schlegelii
期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS, 2023, 卷号: 46, 页码: 10
作者:
Shen, Xing
;
Li, Xian
;
Jia, Chaofeng
;
Li, Jun
;
Chen, Shuyin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/13
Anosmic
Black porgy
HPLC-MS
Metabolites
Metabolic pathways
Activity labelled molecular networking fuels the antioxidation active molecules profile of Ginger
期刊论文
FOOD CHEMISTRY, 2023, 卷号: 424
作者:
Wang, Qiqi
;
Chen, Tao
;
La, Mencuo
;
Song, Zhibo
;
Gao, Mengze
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2023/12/01
Is negative density-dependent reproduction regulated by density-induced stress in root voles? Two field experiments
期刊论文
ECOLOGY AND EVOLUTION, 2022, 卷号: 12, 期号: 5
作者:
Shang, GZ
;
Du, SY
;
Yang, YB
;
Wu, Y
;
Cao, YF
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2022/12/02
Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Zou, Hui-xi
;
Zhang, Yu-feng
;
Zhong, Da-fang
;
Jiang, Yong
;
Liu, Fei
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  |  
浏览/下载:17/0
  |  
提交时间:2022/01/04
furmonertinib
autoinduction
food effect
alkaline phosphatase
body weight
pharmacokinetics
modeling and simulation
NSCLC
A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:
Zhou, Jun
;
Zhan, Yan
;
Zhong, Dafang
;
Chen, Xiaoyan
;
Zhang, Yifan
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2021/11/04
chimmitecan
mass spectrometry
pharmacokinetics
simmitecan
solid tumors
Itraconazole and rifampicin, as CYP3A modulators but not P-gp modulators, affect the pharmacokinetics of almonertinib and active metabolite HAS-719 in healthy volunteers
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Liu, Lu
;
Li, Wei
;
Yang, Le
;
Guo, Zi-tao
;
Xue, Hao
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2021/08/17
almonertinib
itraconazole
rifampicin
drug metabolism
drug interaction
CYP3A
P-gp
pharmacokinetics
Discovery, Structure-Activity Relationship, and Mechanistic Studies of 1-((3R,4S)-3-((Dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2-(2,4,5-trifluorophenyl)ethan-1-one as a Novel Potent Analgesic
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9458-9483
作者:
Huang, Huoming
;
Li, Xueping
;
Xie, Peng
;
Li, Xinwei
;
Xu, XueJun
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/08/17
The engineered biphenyl dioxygenases enhanced the metabolism of dibenzofuran
期刊论文
INTERNATIONAL BIODETERIORATION & BIODEGRADATION, 2021, 卷号: 161, 页码: 9
作者:
Wang, Yuan
;
Sun, Chengcheng
;
Min, Jun
;
Li, Bingjun
;
Li, Junde
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2021/10/20
Dibenzofuran
Burkholderia xenovorans LB400
Biphenyl dioxygenase
Enzyme engineering
Regiospecificity
Biocatalysts
Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Meng, Jian
;
Zhang, Hua
;
Bao, Jing-jing
;
Chen, Zhen-dong
;
Liu, Xiao-yun
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/06/11
metabolism
mass balance
distribution
covalent binding
furmonertinib
Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Meng, Jian
;
Zhang, Hua
;
Bao, Jing-jing
;
Chen, Zhen-dong
;
Liu, Xiao-yun
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2021/06/11
metabolism
mass balance
distribution
covalent binding
furmonertinib
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