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上海药物研究所 [3]
复旦大学上海医学院 [3]
上海生物化学与细胞生... [3]
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期刊论文 [9]
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2020 [1]
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Hematology... [3]
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Pharmacokinetics, mass balance, and metabolism of [C-14]vicagrel, a novel irreversible P2Y(12) inhibitor in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Zheng, Yuan-dong
;
Zhang, Hua
;
Zhan, Yan
;
Bian, Yi-cong
;
Ma, Sheng
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/05/24
vicagrel
[C-14]vicagrel
vicagrel pharmacokinetics
vicagrel metabolism
mass balance
P2Y(12) receptor inhibitor
Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y(12) inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 127, 页码: 151-160
作者:
Li, Cai
;
Zhang, Yifan
;
Chen, Weili
;
Lu, Youming
;
Li, Wei
收藏
  |  
浏览/下载:102/0
  |  
提交时间:2019/01/08
Vicagrel
Clopidogrel
P2Y(12) inhibitor
Pharmacokinetics
Active metabolite
Thienopyridine
Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y(12) inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 127
作者:
Liu, Cai
;
Zhang, Yifan
;
Chen, Weili
;
Lu, Youming
;
Li, Wei
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/05
Vicagrel
Clopidogrel
P2Y(12) inhibitor
Pharmacokinetics
Active metabolite
Thienopyridine
Development and validation of a sensitive and rapid UHPLC-MS/MS method for the simultaneous quantification of the common active and inactive metabolites of vicagrel and clopidogrel in human plasma
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018, 卷号: 149, 页码: 394-402
作者:
Liu, Cai
;
Lu, Youming
;
Sun, Hongbin
;
Yang, Jin
;
Liu, Yongqiang
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Vicagrel
Clopidogrel
Active metabolite
LC-MS/MS
Human plasma
P2Y(12) inhibitor
Salvianolic acid B inhibits platelets as a P2Y(12) antagonist and PDE inhibitor: Evidence from clinic to laboratory
期刊论文
THROMBOSIS RESEARCH, 2014, 卷号: 134, 期号: 4, 页码: 866-876
作者:
Liu, L
;
Li, J
;
Zhang, Y
;
Zhang, SH
;
Ye, JQ
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2015/07/22
acute coronary syndrome
antiplatelet
P2Y(12) receptor antagonist
phosphodiesterase inhibitor
salvianolate
Salvianolic acid B inhibits platelets as a P2Y(12) antagonist and PDE inhibitor: Evidence from clinic to laboratory
期刊论文
THROMBOSIS RESEARCH, 2014, 卷号: 134, 期号: 4
作者:
Liu, Lei
;
Li, Jian
;
Zhang, Yan
;
Zhang, Shenghui
;
Ye, Jianqin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/19
acute coronary syndrome
antiplatelet
P2Y(12) receptor antagonist
phosphodiesterase inhibitor
salvianolate
BF061, a novel antiplatelet and antithrombotic agent targeting P2Y(12) receptor and phosphodiesterase
期刊论文
THROMBOSIS AND HAEMOSTASIS, 2011, 卷号: 106, 期号: 6, 页码: 1203-1214
作者:
Hu, L
;
Fan, ZC
;
Du, HG
;
Ni, R
;
Zhang, S
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2015/07/22
Antiplatelet
antithrombotic
BF061
PDE inhibitor
P2Y(12) receptor antagonist
BF061, a novel antiplatelet and antithrombotic agent targeting P2Y(12) receptor and phosphodiesterase
期刊论文
THROMBOSIS AND HAEMOSTASIS, 2011, 卷号: 106, 期号: 6
作者:
Hu, Liang
;
Fan, Zhichao
;
Du, Hongguang
;
Ni, Ran
;
Zhang, Si
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/19
Antiplatelet
antithrombotic
BF061
PDE inhibitor
P2Y(12) receptor antagonist
BF0801, a novel adenine derivative, inhibits platelet activation via phosphodiesterase inhibition and P2Y(12) antagonism
期刊论文
THROMBOSIS AND HAEMOSTASIS, 2010, 卷号: 104, 期号: 4, 页码: 845-857
作者:
Zhang, S
;
Hu, LA
;
Du, HG
;
Guo, Y
;
Zhang, Y
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2015/07/22
Antiplatelet
adenine derivative
cAMP
P2Y(12)
phosphodiesterase
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