×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [6]
复旦大学上海医学院 [2]
北京大学 [1]
大连理工大学 [1]
兰州大学 [1]
上海生物化学与细胞生... [1]
更多...
内容类型
期刊论文 [11]
会议论文 [1]
发表日期
2019 [2]
2018 [2]
2017 [2]
2016 [1]
2015 [1]
2013 [2]
更多...
学科主题
Biochemist... [1]
biochemist... [1]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共12条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
发表日期升序
发表日期降序
提交时间升序
提交时间降序
题名升序
题名降序
作者升序
作者降序
Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y(12) inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 127, 页码: 151-160
作者:
Li, Cai
;
Zhang, Yifan
;
Chen, Weili
;
Lu, Youming
;
Li, Wei
收藏
  |  
浏览/下载:102/0
  |  
提交时间:2019/01/08
Vicagrel
Clopidogrel
P2Y(12) inhibitor
Pharmacokinetics
Active metabolite
Thienopyridine
Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y(12) inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 127
作者:
Liu, Cai
;
Zhang, Yifan
;
Chen, Weili
;
Lu, Youming
;
Li, Wei
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/05
Vicagrel
Clopidogrel
P2Y(12) inhibitor
Pharmacokinetics
Active metabolite
Thienopyridine
Discovery and structure-activity relationships study of thieno[2,3-b] pyridine analogues as hepatic gluconeogenesis inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 307-317
作者:
Ma, Fei
;
Liu, Jian
;
Zhou, Tingting
;
Lei, Min
;
Chen, Jing
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2019/01/08
Thienol2,3-b]pyridine derivatives
Structure-activity relationships (SARs)
Hepatic gluconeogenesis
Type 2 diabetes mellitus (T2DM)
Development and validation of a sensitive and rapid UHPLC-MS/MS method for the simultaneous quantification of the common active and inactive metabolites of vicagrel and clopidogrel in human plasma
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018, 卷号: 149, 页码: 394-402
作者:
Liu, Cai
;
Lu, Youming
;
Sun, Hongbin
;
Yang, Jin
;
Liu, Yongqiang
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Vicagrel
Clopidogrel
Active metabolite
LC-MS/MS
Human plasma
P2Y(12) inhibitor
Arylacetamide Deacetylase Is Involved in Vicagrel Bioactivation in Humans
期刊论文
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
作者:
Jiang, Jinfang
;
Chen, Xiaoyan
;
Zhong, Dafang
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
arylacetamide deacetylase
vicagrel
clopidogrel
hydrolytic metabolism
METABOLISM AND PHARMACOKINETICS OF VICAGREL, A NOVEL THIENOPYRIDINE P2Y12 INHIBITOR, COMPARED WITH CLOPIDOGREL IN HEALTHY CHINESE SUBJECTS
会议论文
作者:
Liu, Cai
;
Chen, Xiaoyan
;
Zhong, Dafang
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Enhancing specificity in the Janus kinases: a study on the thienopyridine JAK2 selective mechanism combined molecular dynamics simulation
期刊论文
MOLECULAR BIOSYSTEMS, 2016, 卷号: 12, 期号: 2, 页码: 575-587
作者:
Li, JJ
;
Cheng, P
;
Tu, J
;
Zhai, HL
;
Zhang, XY
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/01/11
Human Liver Cytochrome P450 Enzymes and Microsomal Thiol Methyltransferase Are Involved in the Stereoselective Formation and Methylation of the Pharmacologically Active Metabolite of Clopidogrel
期刊论文
DRUG METABOLISM AND DISPOSITION, 2015, 卷号: 43, 期号: 10, 页码: 1632-1641
作者:
Liu, Cai
;
Chen, Zhaoqiang
;
Zhong, Kan
;
Li, Liang
;
Zhu, Weiliang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
In Vitro Biotransformation Studies of 2-Oxo-clopidogrel: Multiple Thiolactone Ring-Opening Pathways Further Attenuate Prodrug Activation
期刊论文
毒物学领域的化学研究, 2013
Zhu, Yaoqiu
;
Zhou, Jiang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/13
CLOPIDOGREL BIOACTIVATION
ACTIVE METABOLITE
IDENTIFICATION
TICLOPIDINE
RESISTANCE
PRASUGREL
THIENOPYRIDINE
DISPOSITION
INVOLVEMENT
GLUTATHIONE
Current role of glycoprotein IIb/IIIa receptor inhibitors in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention after pretreatment with loading dose thienopyridines
期刊论文
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2013, 卷号: 167, 期号: 2
作者:
Dong, Lili
;
Wang, Yongshi
;
Wu, Boting
;
Shu, Xianhong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/19
Glycoprotein IIb/IIIa receptor inhibitor
Thienopyridine
ST-elevation myocardial infarction
Percutaneous coronary intervention
©版权所有 ©2017 CSpace - Powered by
CSpace