QQ客服 官方微博 反馈留言

浏览/检索结果: 共5条，第1-5条 帮助 限定条件 发表日期：2019     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 Optimization of P2Y(12) Antagonist Ethyl 6-(4-((Benzylsulfonyl)carbarnoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate (AZD1283) Led to the Discovery of an Oral Antiplatelet Agent with Improved Druglike Properties 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 3088-3106 作者:  Kong, Deyu;  Xue, Tao;  Guo, Bin;  Cheng, Jianjun;  Liu, Shunyin 收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01 Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y(12) inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing 期刊论文 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 127, 页码: 151-160 作者:  Li, Cai;  Zhang, Yifan;  Chen, Weili;  Lu, Youming;  Li, Wei 收藏  |  浏览/下载：102/0  |  提交时间：2019/01/08 Vicagrel  Clopidogrel  P2Y(12) inhibitor  Pharmacokinetics  Active metabolite  Thienopyridine   Chinese patients carrying two CYP2C19 LOFs have a more active state of P2Y(12)-G(i) signaling and larger MPV in post-clopidogrel platelets with acute coronary syndrome 期刊论文 INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2019, 卷号: 12, 期号: 7 作者:  Xu, Huajie;  Wu, Hongyi;  Zhao, Xin;  Zhang, Yan;  Chen, She 收藏  |  浏览/下载：18/0  |  提交时间：2019/12/05 CYP2C19  clopidogrel  P2Y(12)  VASP  Akt  MPV   Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y(12) inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing 期刊论文 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 127 作者:  Liu, Cai;  Zhang, Yifan;  Chen, Weili;  Lu, Youming;  Li, Wei 收藏  |  浏览/下载：26/0  |  提交时间：2019/12/05 Vicagrel  Clopidogrel  P2Y(12) inhibitor  Pharmacokinetics  Active metabolite  Thienopyridine   P2Y(12) deficiency in mouse impairs noradrenergic system in brain, and alters anxiety-like neurobehavior and memory 期刊论文 GENES BRAIN AND BEHAVIOR, 2019, 卷号: 18, 期号: 2 作者:  Zheng, F.;  Zhou, Q.;  Cao, Y.;  Shi, H.;  Wu, H. 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/05 anxiety  locomotion  memory  noradrenaline  P2Y(12)