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科研机构
上海药物研究所 [4]
大连化学物理研究所 [3]
复旦大学上海医学院 [2]
昆明动物研究所 [2]
自动化研究所 [1]
中南大学 [1]
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期刊论文 [14]
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Metabolic-related gene pairs signature analysis identifies ABCA1 expression levels on tumor-associated macrophages as a prognostic biomarker in primary IDHWT glioblastoma
期刊论文
FRONTIERS IN IMMUNOLOGY, 2022, 卷号: 13
作者:
Wang, Shiqun
;
Li, Lu
;
Zuo, Shuguang
;
Kong, Lingkai
;
Wei, Jiwu
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2022/12/22
primary glioblastoma
wild-type isocitrate dehydrogenase
metabolic-related gene pairs
prognosis
tumor-associated macrophages
ABCA1
Reprogramming the immunosuppressive microenvironment of IDH1 wild-type glioblastoma by blocking Wnt signaling between microglia and cancer cells
期刊论文
ONCOIMMUNOLOGY, 2021, 卷号: 10, 期号: 1, 页码: 13
作者:
Fan, Dandan
;
Yue, Qi
;
Chen, Jian
;
Wang, Cong
;
Yu, Ruilin
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/17
Wnt/beta-catenin
IDH1-wildtype glioblastoma
Microglia
Phenotypic polarization
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13
作者:
Wang, Zheng
;
Li, Zeng-xia
;
Zhao, Wen-cao
;
Huang, Hong-bo
;
Wang, Jia-qi
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2020/12/24
grincamycin B
marine natural product
isocitrate dehydrogenase 1
apoptosis
ER stress
intracellular ROS
Zebrafish embryos
hematological malignancies
Pharmacological characterization of TQ05310, a potent inhibitor of isocitrate dehydrogenase 2 R140Q and R172K mutants
期刊论文
CANCER SCIENCE, 2019, 页码: 9
作者:
Gao, Mingzhao
;
Zhu, Hongmei
;
Fu, Li
;
Li, Yun
;
Bao, Xubin
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
AG-221
IDH2
leukemia
R140Q
R172K
Integrated Metabolomics and Lipidomics Analyses Reveal Metabolic Reprogramming in Human Glioma with IDH1 Mutation
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3, 页码: 960-969
作者:
Xu, Guowang
;
Zhou, Lina
;
Wang, Zhichao
;
Hu, Chunxiu
;
Zhang, Chaoqi
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2019/06/20
glioma
IDH1
metabolomics
lipidomics
metabolic reprogramming
Integrated metabolomics and lipidomics analyses reveal metabolic reprogramming in human glioma with idh1 mutation
期刊论文
Journal of proteome research, 2019, 卷号: 18, 期号: 3, 页码: 960-969
作者:
Zhou, Lina
;
Wang, Zhichao
;
Hu, Chunxiu
;
Zhang, Chaoqi
;
Kovatcheva-Datchary, Petia
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2019/05/08
Glioma
Idh1
Metabolomics
Lipidomics
Metabolic reprogramming
IDH mutation-specific radiomic signature in lower-grade gliomas
期刊论文
AGING-US, 2019, 卷号: 11, 期号: 2, 页码: 673-696
作者:
Liu, Xing
;
Li, Yiming
;
Li, Shaowu
;
Fan, Xing
;
Sun, Zhiyan
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2019/07/12
isocitrate dehydrogenase
lower grade gliomas
radiomic signature
transcriptome-radiomic analysis
prognostic signature
3-(7-Azaindolyl)-4-indolylmaleimides as a novel class of mutant isocitrate dehydrogenase-1 inhibitors: Design, synthesis, and biological evaluation
期刊论文
ARCHIV DER PHARMAZIE, 2018, 卷号: 351, 期号: 10
作者:
Hu, Yuanyuan
;
Gao, Anhui
;
Liao, Honghui
;
Zhang, Mengmeng
;
Xu, Gaoya
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
2-hydroxyglutaric acid
3-(7-azaindoyl)-4-indolylmaleimides
isocitrate dehydrogenase 1 inhibitors
tumor
Wild-type IDH2 promotes the Warburg effect and tumor growth through HIF1 alpha in lung cancer
期刊论文
THERANOSTICS, 2018, 卷号: 8, 期号: 15
作者:
Li, Jiangjiang
;
He, Ya
;
Tan, Zheqiong
;
Lu, Jingchen
;
Li, Liling
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/05
isocitrate dehydrogenase 2
lung cancer
Warburg effect
tumor growth
HIF1-alpha
Anatomical location differences between mutated and wild-type isocitrate dehydrogenase 1 in low-grade gliomas
期刊论文
INTERNATIONAL JOURNAL OF NEUROSCIENCE, 2017, 卷号: 127, 期号: 10
作者:
Yu, Jinhua
;
Shi, Zhifeng
;
Ji, Chunhong
;
Lian, Yuxi
;
Wang, Yuanyuan
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Low-grade glioma
anatomic location
IDH1
MRI
image analysis
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