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期刊论文 [9]
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Tranylcypromine and 6-trifluoroethyl thienopyrimidine hybrid as LSD1 inhibitor
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 844-847
作者:
Wang, Xiaowen
;
Su, Mingbo
;
Li, You
;
Liu, Tongchao
;
Wang, Yujie
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
LSD1 inhibitor
Tranylcypromine
Menin-MLL1 protei n-protein interaction inhibitor
MV4-11 antiproliferative activity
Structure activity relationship
Synthesis of Novel Analogs of Thieno[2,3-d] Pyrimidin-4(3H)-ones as Selective Inhibitors of Cancer Cell Growth
期刊论文
BIOMOLECULES, 2019, 卷号: 9, 期号: 10, 页码: 1-10
作者:
Zhang, S (Zhang, Sheng)[ 1 ]
;
Liu, FZ (Liu, Feize)[ 2,3 ]
;
Hou, XL (Hou, Xueling)[ 2 ]
;
Cao, JG (Cao, Jianguo)[ 1 ]
;
Dai, XL (Dai, Xiling)[ 1 ]
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/01/15
thienopyrimidine
thieno[2,3-d] pyrimidinone
anticancer
Discovery of new thienopyrimidine derivatives as potent and orally efficacious phosphoinositide 3-kinase inhibitors
期刊论文
2018, 卷号: 26, 期号: 3, 页码: 637-646
作者:
Lin, Songwen
;
Wang, Chunyang
;
Ji, Ming
;
Wu, Deyu
;
Lv, Yuanhao
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Phosphoinositide 3-kinase inhibitors
Anti-tumor activities
Thienopyrimidine
Acetylation
Design, synthesis and biological evaluation of thienopyrimidine hydroxamic acid based derivatives as structurally novel histone deacetylase (HDAC) inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 128, 页码: 293-299
作者:
Wang, Jiang
;
Su, Mingbo
;
Li, Tingting
;
Gao, Anhui
;
Yang, Wei
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
HDAC inhibitor
Anti-proliferation
Western blot
Thienopyrimidine
Structure-activity relationship
Design and synthesis of benzylpiperidine inhibitors targeting the menin-mll1 interface
期刊论文
Bioorganic & medicinal chemistry letters, 2016, 卷号: 26, 期号: 18, 页码: 4472-4476
作者:
Ren, Jing
;
Xu, Wei
;
Tang, Le
;
Su, Minbo
;
Chen, Danqi
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/05/09
Menin
Mixed lineage leukemia
Mll1
Sar
Inhibitor
Design and synthesis of benzylpiperidine inhibitors targeting the menin-MLL1 interface
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 18, 页码: 4472-4476
作者:
Ren, Jing
;
Xu, Wei
;
Tang, Le
;
Su, Minbo
;
Chen, Danqi
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Menin
Mixed lineage leukemia
MLL1
SAR
Inhibitor
Design, synthesis, and biological evaluation of thienopyrimidine derivatives as DPP IV inhibitors for the treatment of type 2 diabetes
会议论文
作者:
Wang, Jiang
;
Liu, Hong
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  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
A thienopyrimidine derivative induces growth inhibition and apoptosis in human cancer cell lines via inhibiting Aurora B kinase activity
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 65
作者:
Li, Jie
;
Hu, Hairong
;
Lang, Qingyu
;
Zhang, Haoxing
;
Huang, Qiang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/19
Aurora B
Small-molecule inhibitor
Molecular modeling
ATP-competitive
Growth inhibition
Apoptosis
The highly potent and selective dipeptidyl peptidase IV inhibitors bearing a thienopyrimidine scaffold effectively treat type 2 diabetes
期刊论文
European Journal of Medicinal Chemistry, 2011, 卷号: 46, 期号: 1, 页码: 71-76
Wenhui Hu
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2012/10/31
The highly potent and selective dipeptidyl peptidase IV inhibitors bearing a thienopyrimidine scaffold effectively treat type 2 diabetes
期刊论文
European Journal of Medicinal Chemistry, 2011, 卷号: 46, 期号: 1, 页码: 71-76
作者:
Wenhui Hu
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  |  
浏览/下载:8/0
  |  
提交时间:2018/12/13
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