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JUNO physics and detector
期刊论文
PROGRESS IN PARTICLE AND NUCLEAR PHYSICS, 2022, 卷号: 123, 页码: 51
作者:
Abusleme, Angel
;
Adam, Thomas
;
Ahmad, Shakeel
;
Ahmed, Rizwan
;
Aiello, Sebastiano
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2022/04/11
JUNO
neutrino physics
neutrino detector
CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Cao, Jiang-yan
;
Qi, Shuang
;
Wu, Hong
;
Wang, Ao-li
;
Liu, Qing-wang
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2022/03/28
HER2
breast cancers
gastric cancers
irreversible inhibitor
drug resistance
Genomic basis of the giga-chromosomes and giga-genome of tree peony Paeonia ostii
期刊论文
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1
作者:
Yuan, Junhui
;
Jiang, Sanjie
;
Jian, Jianbo
;
Liu, Mingyu
;
Yue, Zhen
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/07
The design and sensitivity of JUNO's scintillator radiopurity pre-detector OSIRIS
期刊论文
EUROPEAN PHYSICAL JOURNAL C, 2021, 卷号: 81, 期号: 11, 页码: 33
作者:
Abusleme, Angel
;
Adam, Thomas
;
Ahmad, Shakeel
;
Ahmed, Rizwan
;
Aiello, Sebastiano
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2021/12/13
Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17
作者:
Xie, Hong-Xu
;
Zhang, Juan
;
Li, Yue
;
Zhang, Jin-He
;
Liu, Shan-Kui
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2021/11/04
Tetrahydrobenzo[b]thiophen-2-yl)urea
alpha-Glucosidase inhibitors
Non-competitive inhibitor
Molecular docking
Anti-hyperglycaemic activity
Type 2 diabetes
Disrupted intrinsic functional brain topology in patients with major depressive disorder
期刊论文
MOLECULAR PSYCHIATRY, 2021, 页码: 9
作者:
Yang, Hong
;
Chen, Xiao
;
Chen, Zuo-Bing
;
Li, Le
;
Li, Xue-Ying
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2021/09/24
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Wang, Lin
;
Wu, Yan
;
Yao, Sheng
;
Ge, Huan
;
Zhu, Ya
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  |  
浏览/下载:85/0
  |  
提交时间:2021/11/04
SARS-CoV-2
natural products
virtual screening
spike protein
protein-protein interaction modulators
A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Ren, Peng-xuan
;
Shang, Wei-juan
;
Yin, Wan-chao
;
Ge, Huan
;
Wang, Lin
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2021/06/11
SARS-CoV-2 inhibitors
RdRp
host ribosome
Virus RNA
Disrupted hemispheric connectivity specialization in patients with major depressive disorder: Evidence from the REST-meta-MDD Project
期刊论文
JOURNAL OF AFFECTIVE DISORDERS, 2021, 卷号: 284, 页码: 217-228
作者:
Ding, Yu-Dan
;
Yang, Ru
;
Yan, Chao-Gan
;
Chen, Xiao
;
Bai, Tong-Jian
收藏
  |  
浏览/下载:168/0
  |  
提交时间:2021/04/19
Major depressive disorder
hemispheric asymmetry
parameter of asymmetry
fMRI Abbreviations ACC, Anterior cingulate gyrus
DLPFC, Dorsolateral prefrontal cortex
DMN, Default mode network
DPARSF, Data Processing Assistant for Resting-State fMRI
DSM, Diagnosic and Statistical Manual of Mental Disorders
EEG, Electroencephalographic
FC, Functional connectivity
FDR, False discovery rate
FEDN, First-episode, drug-naive
FEF, Frontal eye fields
fMRI, Functional magnetic resonance imaging
HAMD, Hamilton Depression Rating Scale
HC, Healthy control
IFG, Inferior frontal gyrus
IPL, Inferior parietal lobule
IPS/SPL, Intraparietal sulcus/superior parietal lobule
LMM, Linear mixed model
MDD, Major depressive disorder
MFG, Middle frontal gyrus
MTG, Middle temporal gyrus
PAS, Parameter of asymmetry
PCC, Posterior cingulate cortex
PET, Positron emission tomography
ROIs, Regions of interest
rs-fMRI, Resting-state fMRI
rTMS, repetitive transcranial magnetic stimulation
STS, Superior temporal sulcus
VMHC, Voxel-mirrored homotopic connectivity
Discovery of New alpha-Glucosidase Inhibitors: Structure-Based Virtual Screening and Biological Evaluation
期刊论文
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 9
作者:
Liu, Shan-Kui
;
Hao, Haifang
;
Bian, Yuan
;
Ge, Yong-Xi
;
Lu, Shengyuan
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2021/05/24
α
-glycosidase
virtual screening
cytotoxicity
type 2 diabetes
molecular docking
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