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科研机构
江苏大学 [6]
兰州大学 [6]
上海药物研究所 [5]
山东大学 [3]
水生生物研究所 [2]
昆明医科大学 [2]
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期刊论文 [43]
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Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 12, 页码: 2272-2298
作者:
Ding, Chunyong
;
Song, Zilan
;
Shen, Ancheng
;
Chen, Tingting
;
Zhang, Ao
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Immunotherapy
Anti-tumor
cGAS
STING
TBK1
Small molecule modulators
cGAS facilitates sensing of extracellular cyclic dinucleotides to activate innate immunity
期刊论文
EMBO REPORTS, 2019, 卷号: 20, 期号: 4
作者:
Liu, Haipeng
;
Moura-Alves, Pedro
;
Pei, Gang
;
Mollenkopf, Hans-Joachim
;
Hurwitz, Robert
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/05
cyclic dinucleotides
cyclic guanosine monophosphate-adenosine monophosphate synthase
endocytosis
pathogen-associated molecular pattern
Cinaciguat in combination with insulin induces a favorable effect on implant osseointegration in type 2 diabetic rats
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 118
作者:
Jia, Tingting
;
Wang, Ya-nan
;
Zhang, Jiajia
;
Hao, Xinyu
;
Zhang, Dongjiao
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
Type 2 diabetes mellitus
Cinaciguat
Cyclic guanosine monophosphate
(cGMP)
Protein kinase G II (PKG II)
Insulin
Osseointegration
Effects on larval metamorphosis in the mussel Mytilus coruscus of compounds that act on downstream effectors of G-protein-coupled receptors
期刊论文
JOURNAL OF THE MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM, 2018, 卷号: 98, 期号: 2, 页码: 333-339
作者:
Liang, Xiao
;
Chen, Yu-Ru
;
Gao, Wei
;
Guo, Xing-Pan
;
Ding, De-Wen
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/08/19
Mytilus coruscus
larval metamorphosis
pharmacological compounds
G protein-coupled receptor
Effects on larval metamorphosis in the mussel Mytilus coruscus of compounds that act on downstream effectors of G-protein-coupled receptors
期刊论文
JOURNAL OF THE MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM, 2018, 卷号: 98, 期号: 2, 页码: 333-339
作者:
Liang, Xiao
;
Chen, Yu-Ru
;
Gao, Wei
;
Guo, Xing-Pan
;
Ding, De-Wen
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2018/12/07
Mytilus coruscus
larval metamorphosis
pharmacological compounds
G protein-coupled receptor
cGMP is involved in Zn tolerance through the modulation of auxin redistribution in root tips
期刊论文
ENVIRONMENTAL AND EXPERIMENTAL BOTANY, 2018, 卷号: 147, 期号: x, 页码: 22-30
作者:
Zhang, Ping
;
Sun, Liangliang
;
Qin, Jun
;
Wan, Jinpeng
;
Wang, Ruling
收藏
  |  
浏览/下载:152/0
  |  
提交时间:2018/03/07
Stem-cell Niche
Arabidopsis-thaliana
Nitric-oxide
Cyclic-gmp
Differential Expression
Aux/iaa Proteins
Zinc Tolerance
Soybean Roots
Growth
Transport
A terbium-based metal-organic framework@gold nanoparticle system as a fluorometric probe for aptamer based determination of adenosine triphosphate
期刊论文
MICROCHIMICA ACTA, 2018, 卷号: 185, 期号: 8
作者:
Qu, Fei
;
Sun, Chao
;
Lv, Xiaoxia
;
You, Jinmao
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/11/26
Lanthanide MOF
Aptasensing
Aptamer-ATP complex
Aggregation
Gold nanoparticles
Dispersion
ATP-binding aptamer
ATP
ssDNA
Biosensing
Grape seed proanthocyanidin extract alleviates urethral dysfunction in diabetic rats through modulating the NO-cGMP pathway
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 卷号: 15, 期号: 1, 页码: 1053-1061
作者:
Zhang, Bing
;
Zhang, Zhaocun
;
Ji, Hong
;
Shi, Hui
;
Chen, Shouzhen
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
diabetes mellitus
urethra
oxidative stress
grape seed
proanthocyanidin
nitric oxide-cyclic guanosine monophosphate pathway
Cyclic Guanosine Monophosphate (cGMP)-Dependent Protein Kinase II Blocks Epidermal Growth Factor (EGF)/Epidermal Growth Factor Receptor (EGFR)-Induced Biological Effects on Osteosarcoma Cells
期刊论文
MEDICAL SCIENCE MONITOR, 2018, 卷号: 24, 页码: 1997-2002
作者:
Li, Dapeng[1]
;
Hua, Ye[2]
;
Jiang, Lu[3]
;
Huang, Yonghui[4]
;
Yue, Jiawei[5]
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/24
Cell Proliferation
Cyclic GMP-Dependent Protein Kinase Type II
Epidermal Growth Factor
Osteosarcoma
Receptor
Epidermal Growth Factor
Transcellular Cell Migration
Formaldehyde regulates vascular tensions through nitric oxide-cGMP signaling pathway and ion channels
期刊论文
Chemosphere, 2018, 卷号: 193, 页码: 60-73
作者:
Zhang, Quanxi*
;
Tian, Peiru
;
Zhai, Miaomiao
;
Lei, Xiaodong
;
Yang, Zhenhua
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/23
Formaldehyde
Thoracic aorta ring
Vascular tension
Ion channels
Signal pathway
4-AP
4-aminopyridine
ACh
acetylcholine
l-NAME
l
NG-nitro-l-arginine methyl ester
l
ACE
angiotensin-converting enzyme
VSMCs
vascular smooth muscle cells
BKCa
big-conductance Ca2+-activated K+ channel
FA
formaldehyde
IbTx
iberiotoxin
iNOS
inducible nitric oxide synthase
KATP
ATP-sensitive K+ channel
eNOS
endothelial nitric oxide synthase
Kv
voltage-dependent K+ channel
sGC
soluble guanylate cyclase
NE
norepinephrine
nNOS
neuronal nitric oxide synthase
NS-2028
4H-8-bromo-1,2,4-oxadiazolo(3,4-d)benz(b)(1,4)oxazin-1-one
PGI2
prostacyclin
PKC
protein kinase C
cGMP
cyclic guanosine monophosphate
TEA
tetraethylammonium
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