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上海药物研究所 [4]
暨南大学 [3]
南华大学 [2]
复旦大学上海医学院 [2]
自然资源部第一海洋研... [2]
深圳先进技术研究院 [1]
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期刊论文 [18]
发表日期
2018 [18]
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Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 17, 页码: 3486-3503
作者:
Dong, Jiajia
;
Olaleye, Olajide E.
;
Jiang, Rongrong
;
Li, Jing
;
Lu, Chuang
收藏
  |  
浏览/下载:99/0
  |  
提交时间:2019/01/08
The mTOR inhibitor AZD8055 overcomes tamoxifen resistance in breast cancer cells by down-regulating HSPB8
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 8, 页码: 1338-1346
作者:
Shi, Jia-jie
;
Chen, Si-meng
;
Guo, Chen-Liang
;
Li, Yi-xue
;
Ding, Jian
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
tamoxifen resistance
HSPB8
AZD8055
estrogen receptor
mTOR inhibitor
Experimental and Simulation Identification of Xanthohumol as an Inhibitor and Substrate of ABCB1
期刊论文
APPLIED SCIENCES-BASEL, 2018, 卷号: 8, 期号: 5
作者:
Liu, Fangming
;
Hoag, Hannah
;
Wu, Chun
;
Liu, Haizhou
;
Yin, Hua
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/08/19
xanthohumol
doxorubicin resistance
synergism
ABCB1
Experimental and Simulation Identification of Xanthohumol as an Inhibitor and Substrate of ABCB1
期刊论文
APPLIED SCIENCES-BASEL, 2018, 卷号: 8, 期号: 5, 页码: 681:1-11
作者:
Liu, Fangming
;
Hoag, Hannah
;
Wu, Chun
;
Liu, Haizhou
;
Yin, Hua
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2018/12/07
xanthohumol
doxorubicin resistance
synergism
ABCB1
Disposition of Mianserin and Cyclizine in UGT2B10-Overexpressing Human Embryonic Kidney 293 Cells: Identification of UGT2B10 as a Novel N-Glucosidation Enzyme and Breast Cancer Resistance Protein as an N-Glucoside Transporter
期刊论文
Drug Metabolism and Disposition, 2018
作者:
Danyi Lu
;
Dong Dong
;
Qian Xie
;
Zhijie Li
;
Baojian Wu
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/31
Upregulation of Breast Cancer Resistance Protein Expression was Decreased in Plasma Membrane of Colon Cancer with Metastasis of Lymphatic Node
期刊论文
CLINICAL LABORATORY, 2018, 卷号: 64, 期号: 3
作者:
Jia, Xiaofang
;
Wu, Ao
;
Zhang, Jiaoli
;
Zeng, Liyan
;
Li, Feng
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
colon cancer
tissue microarray
ABCG2
metastasis
Effect of Neuroinflammation on ABC Transporters: Possible Contribution to Refractory Epilepsy
期刊论文
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS, 2018, 卷号: 17, 期号: 10
作者:
Deng, Xiaolin
;
Xie, Yangmei
;
Chen, Yinghui
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Refractory epilepsy
ABC transporter
P-glycoprotein
breast cancer resistance protein
multidrug resistance-associated protein
neuroinflammation
NF-kappa B
drug resistance
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
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  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Inhibition of kinesin family member 20B sensitizes hepatocellular carcinoma cell to microtubule-targeting agents by blocking cytokinesis
期刊论文
CANCER SCIENCE, 2018, 卷号: 109, 期号: 11, 页码: 3450-3460
作者:
Liu, Xinran
;
Zhang, Xia
;
Chen, Yuchen
;
Meng, Lijing
;
Chen, Hong
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/04/28
Spindle Assembly Checkpoint
Oncogenic Role
Breast-cancer
Mitotic Exit
Liver
Paclitaxel
Adenocarcinoma
Accumulation
Suppression
Resistance
The impact of P-glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors
期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2018, 卷号: 142, 期号: 2, 页码: 381-391
作者:
de Gooijer, Mark C.
;
Zhang, Ping
;
Weijer, Ruud
;
Buil, Levi C. M.
;
Beijnen, Jos H.
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
glioma
pharmacokinetics
MEK inhibitor
ABC transporters
blood-brain-barrier
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