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Natural products with 1,2-oxazine scaffold: occurrence, chemical diversity, bioactivity, synthesis, and biosynthesis 期刊论文
NATURAL PRODUCT REPORTS, 2023, 页码: 27
作者:  Yan, Li-Hong;  Li, Xin;  Wang, Bin-Gui
收藏  |  浏览/下载:2/0  |  提交时间:2023/12/13
Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13
作者:  Wang, Yu-xiang;  Zhang, Xu;  Ma, Qing-yang;  Hu, Lan-dian;  Zhang, Xi
收藏  |  浏览/下载:47/0  |  提交时间:2021/05/24
Inhibition of MAPK/ERK pathway promotes oligodendrocytes generation and recovery of demyelinating diseases 期刊论文
GLIA, 2019, 卷号: 67, 期号: 7, 页码: 1320-1332
作者:  Suo, Na;  Guo, Yu-e;  He, Bingqing;  Gu, Haifeng;  Xie, Xin
收藏  |  浏览/下载:25/0  |  提交时间:2020/07/01
Discovery of N-(4-(6-Acetamidopyrimidin-4-yloxy)phenyl)-2-(2-(trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 2, 页码: 875-892
作者:  Liang, Xiaofei;  Wang, Beilei;  Chen, Cheng;  Wang, Aoli;  Hu, Chen
收藏  |  浏览/下载:19/0  |  提交时间:2020/05/21
HSP70 inhibitor VER155008 suppresses pheochromocytoma cell and xenograft growth by inhibition of PI3K/AKT/mTOR and MEK/ERK pathways 期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2019, 卷号: 12, 期号: 7
作者:  Xu, Feifei;  Lin, Dengqiang;  Jiang, Wen;  Meng, Li;  Xu, Yunze
收藏  |  浏览/下载:36/0  |  提交时间:2019/12/05
SRC and MEK Co-inhibition Synergistically Enhances the Anti-tumor Effect in Both Non-small-cell Lung Cancer (NSCLC) and Erlotinib-Resistant NSCLC 期刊论文
FRONTIERS IN ONCOLOGY, 2019, 卷号: 9
作者:  Yuan, Man;  Xu, Lin-feng;  Zhang, Juan;  Kong, Si-yuan;  Wu, Man
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/05
STAT3 inhibitor sensitized KRAS-mutant lung cancers to RAF innioitor by activating MEK/ERK signaling pathway 期刊论文
AGING-US, 2019, 卷号: 11, 期号: 17
作者:  Wang, Zhenlin;  Yin, Mengchen;  Chu, Peilin;  Lou, Meiqing
收藏  |  浏览/下载:23/0  |  提交时间:2019/12/05
Zoledronic acid enhances the efficacy of the MEK inhibitor trametinib in KRAS mutant cancers 期刊论文
Cancer Letters, 2019, 卷号: Vol.442, 页码: 202-212
作者:  Xinyu Dai;  Hongwei Xia;  Sheng Zhou;  Qiulin Tang;  Feng Bi
收藏  |  浏览/下载:8/0  |  提交时间:2019/02/28
MEK Inhibitor Reverses Metaplasia and Allows Re-Emergence of Normal Lineages in Helicobacter pylori-Infected Gerbils 期刊论文
GASTROENTEROLOGY, 2019, 卷号: 156, 期号: 3, 页码: 577-5810000
作者:  Yang, Qing;  Yasuda, Tomohiko;  Choi, Eunyoung;  Toyoda, Takeshi;  Roland, Joseph T.
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/11
A benzoxazole compound as a novel MEK inhibitor for the treatment of RAS/RAF mutant cancer 期刊论文
2019, 卷号: 145, 期号: 2, 页码: 586-596
作者:  Cheng, Ying;  Wang, Xingkai;  Xia, Xiangying;  Zhang, Wei;  Tian, Hongqi
收藏  |  浏览/下载:5/0  |  提交时间:2020/01/03


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