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Calpain-2 promotes MKP-1 expression protecting cardiomyocytes in both in vitro and in vivo mouse models of doxorubicin-induced cardiotoxicity 期刊论文
ARCHIVES OF TOXICOLOGY, 2019, 卷号: 93, 期号: 4, 页码: 1051-1065
作者:  Zheng, Dong[1];  Su, Zhaoliang[2];  Zhang, Yi[3];  Ni, Rui[4];  Fan, Guo-Chang[5]
收藏  |  浏览/下载:21/0  |  提交时间:2019/12/24
Bexarotent attenuated CCI-induced spinal neuroinflammation and neuropathic pain by targeting MKP-1. 期刊论文
The journal of pain : official journal of the American Pain Society, 2019
作者:  Gui, Yulong;  Duan, Shunyuan;  Xiao, Lihong;  Tang, Jing;  Li, Aiyuan*
收藏  |  浏览/下载:20/0  |  提交时间:2019/12/27
Broad targeting of triptolide to resistance and sensitization for cancer therapy 期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:  Hou, Zhen-yan;  Tong, Xiao-pei;  Peng, Yong-bo;  Zhang, Bi-Kui*;  Yan, Miao*
收藏  |  浏览/下载:50/0  |  提交时间:2019/12/03
ABC  ATP-binding cassette  AKT  V-Akt murine thymoma viral oncogene homolog  ALDH1  aldehyde dehydrogenase 1  AR  androgen receptor  Bad  Bcl-2-associated death promoter  Bak  Bcl-2 homologous antagonist killer  Bax  Bcl-2-associated X protein  Bcl-2  B-cell lymphoma  Bcl-xL  Bcl-extra large  Bcl-xs  Bcl-extra short  BCRP  breast cancer resistance protein  Bid  BH3 interacting domain death agonist  Bik  Bcl-2-interacting killer  BNIP3  Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3  CAF  cancer-associated fibroblast  CAIX  carbonic anhydrase IX  cFLIP  cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein  ChIP  chromatin immunoprecipitation  CI  Combination Index  cIAP1/2  cellular IAP1/2  CML  chronic myelogenous leukemia  CSC  cancer stem cell  DISC  death-inducing signaling complex  DR  death receptor  DRI  Dose Reduction Index  ECM  extracellular matrix  EMT  epithelial-mesenchymal transition  EpCAM  epithelial cell adhesion molecule  GLUT  glucose transporter  GSK3β  glycogen synthase kinase-3β  HIF-1  hypoxia inducible factor-1  HSF1  heat shock factor 1  HSP  heat shock protein  IAP  inhibitor of apoptosis protein  JNK  c-JUN N-terminal kinase  MAPK  mitogen-activated protein kinase  Mcl-1  myeloid leukemia cell differentiation protein  MDM2  murine double minute 2  MDR  multidrug resistance  MKP  MAPK phosphatase  MRP1  multidrug resistance protein 1  NF-κB  nuclear factor-kappaB  pAkt  phosphor-Akt  PARP  poly ADP-ribose polymerase  P-gp  P-glycoprotein  PI3K-PTEN  phosphatidylinositol 3-kinase-phosphatase and tensin homolog  PKC  phosphorylated at Ser9 by protein kinase C  pp2A  protein phosphatase 2A  REST  repressor element-1 silencing transcription factor  SAR  structure-activity relationship  TAM  tumor-associated macrophage  TFIIH  transcription factor IIH  TKI  tyrosine kinase inhibitor  TM  tumor-microenvironment  TRAIL/Apo-2L  TNF-related apoptosis-inducing ligand  tRXRα  the N-terminal truncated form of the nuclear retinoid X receptor-α  TWHF  Tripterygium wilfordii Hook F  VEGF  vascular endothelial growth factor  XIAP  X-linked IAP  XPB  xerodermapigmentosum group B protein  Triptolide  Antineoplastic  Resistance  Sensitization  Mechanism  
Obacunone causes sustained expression of MKP-1 thus inactivating p38 MAPK to suppress pro-inflammatory mediators through intracellular MIF 期刊论文
2018, 卷号: 119, 期号: 1, 页码: 837-849
作者:  Gao, Yuan;  Hou, Rui;  Liu, Fen;  Liu, Haibo;  Fei, Qiaoling
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/03
丝裂原活化蛋白激酶磷酸酶1(MKP-1)去泛素化酶的筛选及验证 学位论文
北京: 中国科学院大学, 2017
作者:  杨光玺
收藏  |  浏览/下载:47/0  |  提交时间:2019/09/24
MKP1通过抑制JNK信号途径减轻淀粉样蛋白的神经毒性作用 期刊论文
中风与神经疾病杂志, 2017, 卷号: 34, 期号: 12
作者:  孙晶(1);  范佳(2);  王婷婷(3);  侯玮琛(4);  郑胜哲(5)
收藏  |  浏览/下载:15/0  |  提交时间:2019/12/05
MKP1  JNK  MAPK  炎症  氧化应激  
MKP-1和MKP-3与疼痛关系的研究进展 期刊论文
中国疼痛医学杂志, 2016, 卷号: 22, 期号: 4, 页码: 301-304
作者:  杨园园;  石翊飒;  周海娇
收藏  |  浏览/下载:5/0  |  提交时间:2017/04/01
MKP-1  MKP-3  MAPKs  疼痛  
MKP-1对NaF作用成釉细胞引起 pERK1/2下调的调控作用 学位论文
2015
作者:  苏家丽
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/02
MKP-1 is a target of miR-210 and mediate the negative regulation of miR-210 inhibitor on hypoxic hPASMC proliferation 期刊论文
Cell biology international., 2015, 卷号: 39, 期号: 1, 页码: 113-120
作者:  Jin, Youpeng;  Pang, Tingting;  Nelin, Leif D.;  Wang, Wei;  Wang, Yulin
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/17
慢性强迫游泳应激对抑郁行为、B 细胞CLL/淋巴瘤2 关联抗凋亡基因-1 及相关蛋白的影响 学位论文
硕士, 北京: 中国科学院研究生院, 2014
作者:  秦红宁
收藏  |  浏览/下载:95/0  |  提交时间:2016/05/06
应激  抑郁  皮质酮  BAG-1  GR  ERK1/2  MKP-1  


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