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Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y(12) inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 127, 页码: 151-160
作者:
Li, Cai
;
Zhang, Yifan
;
Chen, Weili
;
Lu, Youming
;
Li, Wei
收藏
  |  
浏览/下载:102/0
  |  
提交时间:2019/01/08
Vicagrel
Clopidogrel
P2Y(12) inhibitor
Pharmacokinetics
Active metabolite
Thienopyridine
Clopidogrel Reduces Fibronectin Accumulation and Improves Diabetes-Induced Renal Fibrosis
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2019, 卷号: 15, 期号: 1
作者:
Zheng, Zongyu
;
Cai, Lu
;
Gozal, Evelyne
;
Rane, Madhavi J.
;
Fu, Yaowen
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/05
Diabetes
clopidogrel
fibronectin (FN)
renal fibrosis
Clopidogrel Reduces Fibronectin Accumulation and Improves Diabetes-Induced Renal Fibrosis
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2019, 卷号: 15, 期号: 1
作者:
Zheng, Zongyu
;
Ma, Tianjiao
;
Lian, Xin
;
Gao, Jialin
;
Wang, Weigang
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/05
Diabetes
clopidogrel
fibronectin (FN)
renal fibrosis
Clopidogrel-associated genetic variants on inhibition of platelet activity and clinical outcome for acute coronary syndrome patients
期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2019, 卷号: 124, 期号: 1
作者:
Li, Xiaoye
;
Wang, Zi
;
Wang, Qibing
;
Xu, Qing
;
Lv, Qianzhou
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/05
clopidogrel
genetic variants
platelet activity
major adverse cardiovascular events
Chinese patients carrying two CYP2C19 LOFs have a more active state of P2Y(12)-G(i) signaling and larger MPV in post-clopidogrel platelets with acute coronary syndrome
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2019, 卷号: 12, 期号: 7
作者:
Xu, Huajie
;
Wu, Hongyi
;
Zhao, Xin
;
Zhang, Yan
;
Chen, She
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/05
CYP2C19
clopidogrel
P2Y(12)
VASP
Akt
MPV
Beraprost sodium versus clopidogrel for preventing vascular thromboembolic events of arteriovenous fistula in uraemic patients: a retrospective study with a mean 3-year follow-up
期刊论文
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2019, 卷号: 47, 期号: 1
作者:
Wan, Ziming
;
Zhu, Ying
;
Yang, Ruikun
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/12/05
Beraprost sodium
clopidogrel
arteriovenous fistula
vascular thromboembolic event
uraemia
end-stage renal disease
Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y(12) inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 127
作者:
Liu, Cai
;
Zhang, Yifan
;
Chen, Weili
;
Lu, Youming
;
Li, Wei
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/05
Vicagrel
Clopidogrel
P2Y(12) inhibitor
Pharmacokinetics
Active metabolite
Thienopyridine
Loss of dominance of ticagrelor over clopidogrel in East Asian patients with acute coronary syndrome
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2019, 卷号: 12, 期号: 5, 页码: 4528-4539
作者:
Li, Bo
;
Jin, Xiaodong
;
Wang, Linlin
;
Cui, Lifang
;
Zhao, Yunhe
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/11
Ticagrelor
clopidogrel
acute coronary syndrome
East Asian patients
Evaluation of Tolerability, Pharmacokinetics and Pharmacodynamics of Vicagrel, a Novel P2Y12 Antagonist, in Healthy Chinese Volunteers
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Li, Xiaojiao
;
Liu, Ca
;
Zhu, Xiaoxue
;
Wei, Haijing
;
Zhang, Hong
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2019/01/08
vicagrel
pharmacokinetics
pharmacodynamics
safety
clopidogrel
Development and validation of a sensitive and rapid UHPLC-MS/MS method for the simultaneous quantification of the common active and inactive metabolites of vicagrel and clopidogrel in human plasma
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018, 卷号: 149, 页码: 394-402
作者:
Liu, Cai
;
Lu, Youming
;
Sun, Hongbin
;
Yang, Jin
;
Liu, Yongqiang
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Vicagrel
Clopidogrel
Active metabolite
LC-MS/MS
Human plasma
P2Y(12) inhibitor
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