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Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235
作者:
Qu, Bingxue
;
Xu, Yongjin
;
Lu, Yang
;
Zhuang, Weihao
;
Jin, Xinxin
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/12/23
XPO1
Multiple myeloma
MM.1S
N-phenylsulfonamide
Oral administration
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
;
Qu, Bingxue
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
;
Qu, Bingxue
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors
In vitro insights into the role of copper ions released from selective laser melted CoCrW-xCu alloys in the potential attenuation of inflammation and osteoclastogenesis
期刊论文
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY, 2020, 卷号: 41, 页码: 56-67
作者:
Lu, Yanjin
;
Xu, Xiongcheng
;
Yang, Chunguang
;
Ren, Ling
;
Luo, Kai
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  |  
浏览/下载:25/0
  |  
提交时间:2021/02/02
Osteoclast
Selective laser melting
Macrophage
Cu-bearing biomedical alloy
Biocompatibility
fDiscovery of pyrazole-thiophene derivatives as highly Potent, orally active Akt inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 72-85
作者:
Zhan, Wenhu
;
Che, Jinxin
;
Xu, Lei
;
Wu, Yizhe
;
Hu, Xiaobei
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  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Pyrazole-thiophene derivatives
Akt inhibitor
Antitumor
Discovery of 3,4,6-Trisubstituted Piperidine Derivatives as Orally Active, Low hERG Blocking Akt Inhibitors via Conformational Restriction and Structure-Based Design
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 15, 页码: 7264-7288
作者:
Dong, Xiaowu
;
Zhan, Wenhu
;
Zhao, Mengting
;
Che, Jinxin
;
Dai, Xiaoyang
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  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Graphene Thermal Emitter with Enhanced Joule Heating and Localized Light Emission in Air
期刊论文
ACS PHOTONICS, 2019, 卷号: 6, 期号: 8, 页码: 2117-2125
作者:
Luo, Fang
;
Fan, Yansong
;
Peng, Gang
;
Xu, Shuigang
;
Yang, Yaping
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  |  
浏览/下载:30/0
  |  
提交时间:2021/02/02
graphene
Joule heating
thermal radiation
light emission
photonic cavity
Stress-induced epinephrine enhances lactate dehydrogenase A and promotes breast cancer stem-like cells
期刊论文
JOURNAL OF CLINICAL INVESTIGATION, 2019, 卷号: 129, 期号: 3, 页码: 1030-1046
作者:
Li, Dangsheng
;
Cui, Bai
;
Luo, Yuanyuan
;
Tian, Pengfei
;
Peng, Fei
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  |  
浏览/下载:93/0
  |  
提交时间:2019/06/20
Examining Cu content contribution to changes in oxide layer formed on selective-laser-melted CoCrW alloys
期刊论文
APPLIED SURFACE SCIENCE, 2019, 卷号: 464, 页码: 262-272
作者:
Lu, Yanjin
;
Lin, Wenlie
;
Xie, Meiming
;
Xu, Wentao
;
Liu, Yujing
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2021/02/02
Selective laser melting
Antibacterial materials
High-temperature oxidation
CoCr alloys
Examining Cu content contribution to changes in oxide layer formed on selective-laser-melted CoCrW alloys
期刊论文
APPLIED SURFACE SCIENCE, 2019, 卷号: 464, 页码: 262-272
作者:
Lu, Yanjin
;
Lin, Wenlie
;
Xie, Meiming
;
Xu, Wentao
;
Liu, Yujing
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2021/02/02
Selective laser melting
Antibacterial materials
High-temperature oxidation
CoCr alloys
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