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The discovery of a novel series of potential ERR alpha inverse agonists based on p-nitrobenzenesulfonamide template for triple-negative breast cancer in vivo
期刊论文
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 125-134
作者:
Gao, Zhipei
;
Wang, Tianxiao
;
Li, Rui
;
Du, Yongli
;
Lv, Han
收藏
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浏览/下载:40/0
  |  
提交时间:2022/01/18
ERR alpha
TNBC
p-Nitrobenzenesulfonamide
inverse agonist
Network pharmacology combined with molecular docking to explore the potential mechanisms for the antioxidant activity of Rheum tanguticum seeds
期刊论文
BMC COMPLEMENTARY MEDICINE AND THERAPIES, 2022, 卷号: 22, 期号: 1
作者:
Wang, LL
;
Xiong, F
;
Zhao, S
;
Yang, Y
;
Zhou, GY
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浏览/下载:15/0
  |  
提交时间:2022/12/02
Discovery of chiral N-2 '-aryletheryl-1 '-alkoxy-ethyl substituted arylisoquinolones with anti-inflammatory activity from the nucleophilic addition reactions of the thiophenols and oxazolinium
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 11
作者:
Li, Bo
;
Li, Heng
;
Zhu, Zhengdan
;
Xiang, Caigui
;
Xu, Zhijian
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  |  
浏览/下载:99/0
  |  
提交时间:2021/11/04
Anti-inflammatory activity
TNF alpha
ER beta
IBD Arylisoquinolones
Integrated application effects of biochar and plant residue on ammonia loss, heavy metal immobilization, and estrogen dissipation during the composting of poultry manure
期刊论文
WASTE MANAGEMENT, 2021, 卷号: 131, 页码: 117-125
作者:
Zhang, Fengsong
;
Wei, Zhuo
;
Wang, Jim J.
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  |  
浏览/下载:37/0
  |  
提交时间:2021/11/05
17 beta-estradiol
Estrogenic activity
Ammonia
Heavy metal
Molecular Dynamics Simulations Based on 1-Phenyl-4-Benzoyl-1-Hydro-Triazole ERR alpha Inverse Agonists
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 7, 页码: 14
作者:
Gao, Zhipei
;
Du, Yongli
;
Sheng, Xiehuang
;
Shen, Jingkang
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  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
ERRα
inverse agonists
1-phenyl-4-benzoyl-1-hydro-triazole
MD simulations
Case Report: Significant Response to Immune Checkpoint Inhibitor Camrelizumab in a Heavily Pretreated Advanced ER+/HER2-Breast Cancer Patient With High Tumor Mutational Burden
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 10
作者:
Wang, Rong
;
Yang, Yuchen
;
Ye, Wei-Wu
;
Xiang, Jianxing
;
Chen, Songan
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  |  
浏览/下载:44/0
  |  
提交时间:2021/04/26
breast cancer
immunotherapy
biomarker
TMB
NGS
molecular monitoring
Evaluation of the Estrogenic/Antiestrogenic Activities of Perfluoroalkyl Substances and Their Interactions with the Human Estrogen Receptor by Combining In Vitro Assays and In Silico Modeling
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 卷号: 54, 期号: 22, 页码: 14514-14524
作者:
Li, Juan
;
Cao, Huiming
;
Feng, Hongru
;
Xue, Qiao
;
Zhang, Aiqian
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  |  
浏览/下载:24/0
  |  
提交时间:2021/09/14
Structure-Oriented Research on the Antiestrogenic Effect of Organophosphate Esters and the Potential Mechanism
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 卷号: 54, 期号: 22, 页码: 14525-14534
作者:
Li, Juan
;
Cao, Huiming
;
Mu, Yunsong
;
Qu, Guangbo
;
Zhang, Aiqian
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  |  
浏览/下载:25/0
  |  
提交时间:2021/09/14
Tricresyl phosphate isomers exert estrogenic effects via G protein-coupled estrogen receptor-mediated pathways
期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 264, 页码: 1-10
作者:
Ji, Xiaoya
;
Li, Na
;
Ma, Mei
;
Rao, Kaifeng
;
Yang, Rong
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  |  
浏览/下载:31/0
  |  
提交时间:2021/09/15
Tricresyl phosphate isomers
Estrogenic effect
GPER
cAMP
Calcium mobilization
Binding and activation of estrogen related receptor gamma as possible molecular initiating events of hydroxylated benzophenones endocrine disruption toxicity
期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 263, 页码: 1-12
作者:
Zheng, Xiyue
;
Ren, Xiao-Min
;
Zhao, Lixia
;
Guo, Liang-Hong
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  |  
浏览/下载:10/0
  |  
提交时间:2021/09/14
UV-Filters
Hydroxylated benzophenones
Estrogen related receptor gamma
Transcriptional activity
Endocrine disruption
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