CORC

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CORC

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The discovery of a novel series of potential ERR alpha inverse agonists based on p-nitrobenzenesulfonamide template for triple-negative breast cancer in vivo 期刊论文
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 125-134
作者:  Gao, Zhipei;  Wang, Tianxiao;  Li, Rui;  Du, Yongli;  Lv, Han
收藏  |  浏览/下载：38/0  |  提交时间：2022/01/18
Molecular Dynamics Simulations Based on 1-Phenyl-4-Benzoyl-1-Hydro-Triazole ERR alpha Inverse Agonists 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 7, 页码: 14
作者:  Gao, Zhipei;  Du, Yongli;  Sheng, Xiehuang;  Shen, Jingkang
收藏  |  浏览/下载：25/0  |  提交时间：2021/05/24
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:  Yu, Ming-cheng;  Yang, Feng;  Ding, Xiao-yu;  Sun, Nan-nan;  Jiang, Zheng-yuan
收藏  |  浏览/下载：83/0  |  提交时间：2020/12/24
Cryo-EM Structure of the Human Cannabinoid Receptor CB2-G(i) Signaling Complex 期刊论文
CELL, 2020, 卷号: 180, 期号: 4, 页码: 645-+
作者:  Xing, Changrui;  Zhuang, Youwen;  Xu, Ting-Hai;  Feng, Zhiwei;  Zhou, X. Edward
收藏  |  浏览/下载：51/0  |  提交时间：2020/07/01
Designing of novel ERR gamma inverse agonists by molecular modeling studies of docking and 3D-QSAR on hydroxytamoxifen derivatives 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2019, 卷号: 28, 期号: 10, 页码: 1661-1673
作者:  Li, Rui;  Du, Yongli;  Shen, Jingkang
收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01
Discovery of N-indanyl benzamides as potent ROR gamma t inverse agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 167
作者:  Liu, Jin;  Wang, Yonghui;  Shao, Liming;  Liu, Li;  Tian, Jinlong
收藏  |  浏览/下载：21/0  |  提交时间：2019/12/05
A Drug with Lipophilicity-Dependent Potency Can Be Metabolically Stable: Discovery of a Potent and Selective Retinoic Acid Receptor-Related Orphan Receptor C2 (RORC2) Inverse Agonist as an Orally Bioavailable Anti-Inflammatory Agent 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 23, 页码: 10412-10414
作者:  Wang, Yibing;  Liu, Hong
收藏  |  浏览/下载：78/0  |  提交时间：2019/01/08
From ROR gamma t Agonist to Two Types of ROR gamma t Inverse Agonists 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 2
作者:  Huang, Yafei;  Wang, Yonghui;  Cai, Wei;  Tang, Ting;  Liu, Qian
收藏  |  浏览/下载：15/0  |  提交时间：2019/12/05
Molecular Mechanism of Action of RORt Agonists and Inverse Agonists: Insights from Molecular Dynamics Simulation 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 12
作者:  Sun, Nannan;  Yuan, Congmin;  Ma, Xiaojun;  Wang, Yonghui;  Gu, Xianfeng
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/05
Discovery of carbazole carboxamides as novel ROR gamma t inverse agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148
作者:  Huang, Yafei;  Yu, Mingcheng;  Sun, Nannan;  Tang, Ting;  Yu, Fazhi
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/05

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