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上海药物研究所 [25]
厦门大学 [15]
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上海神经科学研究所 [3]
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期刊论文 [70]
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Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Wang, Zuo-wei
;
Zou, Feng-ming
;
Wang, Ao-li
;
Yang, Jing
;
Jin, Rui
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/12/22
AZD4547
RIPK1
inhibitors
SIRS model
anti-necroptosis
Deep learning for predicting immunotherapeutic efficacy in advanced non-small cell lung cancer patients: a retrospective study combining progression-free survival risk and overall survival risk
期刊论文
TRANSLATIONAL LUNG CANCER RESEARCH, 2022, 页码: 23
作者:
He, Bing-Xi
;
Zhong, Yi-Fan
;
Zhu, Yong-Bei
;
Deng, Jia-Jun
;
Fang, Meng-Jie
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/06/10
Tumor biomarkers
immunotherapy
lung neoplasms
programmed cell death 1 receptor (PD-1 receptor)
biostatistics
Peptidic microarchitecture-trapped tumor vaccine combined with immune checkpoint inhibitor or PI3K gamma inhibitor can enhance immunogenicity and eradicate tumors
期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 2, 页码: 13
作者:
Du, Yang
;
Liu, Ye
;
Wang, Di
;
Bai, Hua
;
Wang, Zhijie
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/06/06
immunotherapy
immunogenicity
vaccine
tumor microenvironment
lymphocytes
tumor infiltrating
macrophages
Genome and transcriptome-based characterization of high energy carbon-ion beam irradiation induced delayed flower senescence mutant in Lotus japonicus
期刊论文
BMC Plant Biology, 2021, 卷号: 21, 期号: 1, 页码: 19
作者:
Du,Yan
;
Luo,Shanwei
;
Zhao,Jian
;
Feng,Zhuo
;
Chen,Xia
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/12/08
Lotus japonicus
Flower senescence-delayed
Carbon-ion beam irradiation
Whole genome re-sequencing
RNA-seq
Phytohormone
PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery
期刊论文
AUTOPHAGY, 2021, 卷号: 17, 期号: 10, 页码: 2905-2922
作者:
Tang, Ying
;
Liu, Jinchang
;
Wang, Yu
;
Yang, Li
;
Han, Bing
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/01/04
Autophagy
functional recovery
ischemic stroke
lysophosphatidic acid receptor 5
microglial activation
poly (ADP-ribose) polymerase 14
Prevention of D-GalN/LPS-induced ALI by 18 beta-glycyrrhetinic acid through PXR-mediated inhibition of autophagy degradation
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 5, 页码: 13
作者:
Wu, Shouyan
;
Lu, Henglei
;
Wang, Wenjie
;
Song, Luyao
;
Liu, Meng
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/08/17
Engineering Nanoscale Artificial Antigen-Presenting Cells by Metabolic Dendritic Cell Labeling to Potentiate Cancer Immunotherapy
期刊论文
NANO LETTERS, 2021, 卷号: 21, 期号: 5, 页码: 2094-2103
作者:
Xiao, Ping
;
Wang, Jue
;
Zhao, Zitong
;
Liu, Xiaochen
;
Sun, Xiangshi
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
nanoscale
artificial antigen-presenting cells
metabolic cell labeling
dendritic cells
cancer immunotherapy
Ternary Regulation of Tumor Microenvironment by Heparanase-Sensitive Micelle-Loaded Monocytes Improves Chemo-Immunotherapy of Metastatic Breast Cancer
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 12
作者:
Lang, Tianqun
;
Zheng, Zhong
;
Huang, Xin
;
Liu, Yiran
;
Zhai, Yihui
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2021/05/24
breast cancer
chemo-immunotherapy
heparinase
monocytes
tumor environments
Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 12, 页码: 2272-2298
作者:
Ding, Chunyong
;
Song, Zilan
;
Shen, Ancheng
;
Chen, Tingting
;
Zhang, Ao
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Immunotherapy
Anti-tumor
cGAS
STING
TBK1
Small molecule modulators
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:
Lv, Jianlu
;
Wang, Wei
;
Zhu, Xialin
;
Xu, Xiaoju
;
Yan, Qiuying
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/21
Alzheimer'sdisease
Microglia
AMPK alpha 1
DW14006
Phagocytosis
Neuro-inflammation
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