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CORC

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Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:  Wang, Zuo-wei;  Zou, Feng-ming;  Wang, Ao-li;  Yang, Jing;  Jin, Rui
收藏  |  浏览/下载：17/0  |  提交时间：2022/12/22
Discovery of a series of dimethoxybenzene FGFR inhibitors with 5H-pyrrolo[2,3-b]pyrazine scaffold: structure-activity relationship, crystal structural characterization and and in vivo study 期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 2, 页码: 351-368
作者:  Wei, Peng;  Liu, Bo;  Wang, Ruifeng;  Gao, Yinglei;  Li, Lanlan
收藏  |  浏览/下载：103/0  |  提交时间：2020/07/01
Structure-Based Discovery of a Series of 5H-Pyrrolo[2,3-b]pyrazine FGFR Kinase Inhibitors 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 3
作者:  Jiang, Alan;  Liu, Qiufeng;  Wang, Ruifeng;  Wei, Peng;  Dai, Yang
收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08
Optimization of 1H-indazol-3-amine derivatives as potent fibroblast growth factor receptor inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 16, 页码: 3782-3786
作者:  Cui, Jing;  Peng, Xia;  Gao, Dingding;  Dai, Yang;  Ai, Jing
收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08
Design, synthesis and biological evaluation of pyrazolylaminoquinazoline derivatives as highly potent pan-fibroblast growth factor receptor inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 11, 页码: 2594-2599
作者:  Fan, Jun;  Dai, Yang;  Shao, Jingwei;  Peng, Xia;  Wang, Chen
收藏  |  浏览/下载：9/0  |  提交时间：2019/01/08
Multiple receptor tyrosine kinase activation attenuates therapeutic efficacy of the fibroblast growth factor receptor 2 inhibitor AZD4547 in FGFR2 amplified gastric cancer 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 4
作者:  Chang, Jinjia;  Wang, Shanshan;  Zhang, Zhe;  Liu, Xinyang;  Wu, Zheng
收藏  |  浏览/下载：7/0  |  提交时间：2019/12/19
Design, synthesis and biological evaluation of novel FGFR inhibitors bearing an indazole scaffold 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2015, 卷号: 13, 期号: 28, 页码: 7643-7654
作者:  Liu, Jian;  Peng, Xia;  Dai, Yang;  Zhang, Wei;  Ren, Sumei
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08
Reductions in myeloid-derived suppressor cells and lung metastases using AZD4547 treatment of a metastatic murine breast tumor model 期刊论文
Cellular Physiology and Biochemistry, 2014, 卷号: Vol.33 No.3, 页码: 633-645
作者:  Liu, L.;  Ye, T.H.;  Han, Y.P.;  Song, H.;  Zhang, Y.K.
收藏  |  浏览/下载：5/0  |  提交时间：2019/02/25
AZD4547  Breast  cancer  FGFR  inhibitor  MDSCs  Metastasis  T  cells  

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