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Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine 期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:  Xue, Yaru;  Ren, Xuelian;  Zhu, Zhengdan;  Lei, Peng;  Liu, Mengling
收藏  |  浏览/下载:39/0  |  提交时间:2022/01/18
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity 期刊论文
XENOBIOTICA, 2021, 页码: 13
作者:  Sun, Dongxue;  Gao, Xiaoxia;  Wang, Qiao;  Krausz, Kristopher W.;  Fang, Zhongze
收藏  |  浏览/下载:47/0  |  提交时间:2021/11/04
Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439 期刊论文
ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 7, 页码: 1885-1893
作者:  Shackleford, David M.;  Chiu, Francis C. K.;  Katneni, Kasiram;  Blundell, Scott;  McLaren, Jenna
收藏  |  浏览/下载:59/0  |  提交时间:2021/11/04
The inhibitory effect of 225 frequently-used traditional Chinese medicines for CYP3A4 metabolic enzyme by isoform-specific probe 期刊论文
FITOTERAPIA, 2021, 卷号: 152, 页码: 5
作者:  Wei, Wenlong;  Li, Zhenwei;  Li, Hao-jv;  An, Yaling;  Qu, Hua
收藏  |  浏览/下载:31/0  |  提交时间:2021/08/17
Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:  Wu, Ya-li;  Xue, Ya-ru;  Guo, Zi-tao;  Chen, Zhen-dong;  Ge, Xin-yu
收藏  |  浏览/下载:20/0  |  提交时间:2021/08/17
Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity 期刊论文
DRUG METABOLISM AND DISPOSITION, 2021, 卷号: 49, 期号: 4, 页码: 305-313
作者:  Qiao, Shida;  Feng, Sisi;  Wu, Zhitao;  He, Ting;  Ma, Chen
收藏  |  浏览/下载:26/0  |  提交时间:2021/05/24
Effects of rifampicin on the pharmacokinetics of alflutinib, a selective third-generation EGFR kinase inhibitor, and its metabolite AST5902 in healthy volunteers 期刊论文
INVESTIGATIONAL NEW DRUGS, 2021, 页码: 8
作者:  Zhu, Yun-ting;  Zhang, Yi-fan;  Jiang, Jin-fang;  Yang, Yong;  Guo, Li-xia
收藏  |  浏览/下载:27/0  |  提交时间:2021/05/24
Pharmacokinetic Drug-drug Interaction of Antibiotics Used in Sepsis Care in China 期刊论文
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 1, 页码: 5-23
作者:  Yu, Xuan;  Chu, Zixuan;  Li, Jian;  He, Rongrong;  Wang, Yaya
收藏  |  浏览/下载:67/0  |  提交时间:2021/05/24
Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Tian, Qian-qian;  Zhu, Yun-ting;  Diao, Xing-xing;  Zhang, Xiang-lei;  Xu, Ye-chun
收藏  |  浏览/下载:68/0  |  提交时间:2020/12/24
Study on the anti-tumor mechanism related to immune microenvironment of Bombyx Batryticatus on viral and non-viral infections of hepatocellular carcinoma 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2020, 卷号: 124, 页码: 14
作者:  Yuan, Lingyan;  Bing, Zhitong;  Han, Jiani;  An, Xiaoli;  Liu, Xingkui
收藏  |  浏览/下载:50/0  |  提交时间:2022/01/18


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