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上海药物研究所 [13]
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期刊论文 [21]
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Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 18
作者:
Lan, Xiao-fang
;
Olaleye, Olajide E.
;
Lu, Jun-lan
;
Yang, Wei
;
Du, Fei-fei
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2021/06/11
LianhuaQingwen
glycyrrhetic acid
24-hydroxyglycyrrhetic acid
Gancao-induced pseudoaldosteronism
licorice-induced pseudoaldosteronism
11β
-hydroxysteroid dehydrogenase 2
COVID-19
colonic microbiota
Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
期刊论文
DRUG METABOLISM AND DISPOSITION, 2021, 卷号: 49, 期号: 4, 页码: 305-313
作者:
Qiao, Shida
;
Feng, Sisi
;
Wu, Zhitao
;
He, Ting
;
Ma, Chen
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  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism
期刊论文
NATURE METABOLISM, 2021, 页码: 31
作者:
Xu, Yanyong
;
Li, Yuanyuan
;
Jadhav, Kavita
;
Pan, Xiaoli
;
Zhu, Yingdong
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  |  
浏览/下载:35/0
  |  
提交时间:2021/05/24
Hepatocyte peroxisome proliferator-activated receptor alpha regulates bile acid synthesis and transport
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2019, 期号: 10, 页码: 1396-1411
作者:
Xie, Cen
;
Takahashi, Shogo
;
Brocker, Chad N.
;
He, Shijun
;
Chen, Li
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  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
Peroxisome proliferator-activated receptor alpha
Wy-14,643
Bile acid homeostasis
Farnesoid X receptor
Metabolomics
Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 Are Responsible for Tertiary Oxidations of Deoxycholate Species.
期刊论文
Drug metabolism and disposition: the biological fate of chemicals, 2019
作者:
Zhang Jian
;
Gao Ling-Zhi
;
Chen Yu-Jie
;
Zhu Ping-Ping
;
Yin Shan-Shan
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  |  
浏览/下载:16/0
  |  
提交时间:2019/02/25
UPLC
bile
acid
metabolism/transport
cytochrome
P450
mass
spectrometry/MS
metabolomics
Intestinal Transporter-Associated Drug Absorption and Toxicity
期刊论文
DRUG TRANSPORTERS IN DRUG DISPOSITION, EFFECTS AND TOXICITY, 2019, 卷号: 1141, 页码: 361-405
作者:
Xue, Yaru
;
Ma, Chenhui
;
Hanna, Imad
;
Pan, Guoyu
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  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
Intestinal transporter
Drug absorption
Bile acid transport
BDDCS
Drug-induced toxicity
Upregulation of hbv transcription by sodium taurocholate cotransporting polypeptide at the postentry step is inhibited by the entry inhibitor myrcludex b
期刊论文
Emerging microbes & infections, 2018, 卷号: 7, 页码: 14
作者:
Zhao, Kaitao
;
Liu, Shuhui
;
Chen, Yingshan
;
Yao, Yongxuan
;
Zhou, Ming
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  |  
浏览/下载:87/0
  |  
提交时间:2019/05/08
Functional nanoparticles exploit the bile acid pathway to overcome multiple barriers of the intestinal epithelium for oral insulin delivery
期刊论文
BIOMATERIALS, 2018, 卷号: 151, 页码: 13-23
作者:
Fan, Weiwei
;
Xia, Dengning
;
Zhu, Quanlei
;
Li, Xiuying
;
He, Shufang
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  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Oral delivery
Insulin
Functional nanoparticles
Bile acid pathway
Intestinal epithelium
Endolysosomal escape
An important intestinal transporter that regulates the enterohepatic circulation of bile acids and cholesterol homeostasis: The apical sodium-dependent bile acid transporter (SLC10A2/ASBT)
期刊论文
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY, 2017, 卷号: 41, 期号: 5, 页码: 509-515
作者:
Xiao, Ling
;
Pan, Guoyu
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  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Functional human induced hepatocytes (hiHeps) with bile acid synthesis and transport capacities: A novel in vitro cholestatic model
期刊论文
Scientific Reports, 2016, 卷号: 6
作者:
Ni, Xuan
;
Gao, Yimeng
;
Wu, Zhitao
;
Ma, Leilei
;
Chen, Chen
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  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
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