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Monomeric compounds from traditional Chinese medicine: New hopes for drug discovery in pulmonary fibrosis
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2023, 卷号: 159, 页码: 16
作者:
Wang, Qi
;
Li, Wenjun
;
Hu, Haibo
;
Lu, Xuechao
;
Qin, Song
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/11/15
Pulmonary fibrosis
Monomeric compounds
Flavonoids
Alkaloid
Terpenoids
Phenols
Saponins
Quinones
9.4 T static magnetic field ameliorates imatinib mesylate-induced toxicity and depression in mice
期刊论文
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2022
作者:
Tian, Xiaofei
;
Wang, Chentai
;
Yu, Biao
;
Fan, Yixiang
;
Zhang, Lei
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/22
Static magnetic fields (SMFs)
Imatinib mesylate
Gastrointestinal stromal tumor (GIST)
Drug toxicity
Depression
Fluorescent probes for biomolecule detection under environmental stress
期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2022, 卷号: 431, 页码: 40
作者:
Han, Xiaoyue
;
Wang, Yue
;
Huang, Yan
;
Wang, Xiaoyan
;
Choo, Jaebum
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
Fluorescent probe
Biomolecule
Environmental stress
Physiological
pathological processes
Chemical exposure
Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress via modulation of Keap1/Nrf2 signaling pathway
期刊论文
FREE RADICAL RESEARCH, 2022
作者:
Qi, Yajun
;
Fu, Shuang
;
Pei, Donggen
;
Fang, Qilu
;
Xin, Wenxiu
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2022/12/23
Luteolin
cisplatin
oxidative stress
Keap1
Nrf2
Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Dong, Ying
;
Tang, Bi-xi
;
Wang, Qi
;
Zhou, Li-wei
;
Li, Cong
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2022/01/04
idiopathic pulmonary fibrosis
DDRs
kinase inhibitor
indazole derivatives
XBLJ-13
nintedanib
bleomycin-induced pulmonary fibrosismouse model
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity
期刊论文
XENOBIOTICA, 2021, 页码: 13
作者:
Sun, Dongxue
;
Gao, Xiaoxia
;
Wang, Qiao
;
Krausz, Kristopher W.
;
Fang, Zhongze
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/11/04
CYP
podophyllotoxin metabolism
liver microsomes
recombinant drug-metabolizing enzymes
hepatic and intestinal toxicity
Triptolide analog LLDT-8 ameliorates psoriasis-like dermatitis in BALB/c mice via suppressing the IL-36 alpha signaling pathway
期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11
作者:
Qi, Qing
;
Li, Qian
;
Zhu, Hongwen
;
Lu, Huimin
;
Yang, Xiaoqian
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/08/17
Triptolide
LLDT-8
Psoriasis
IL-36 alpha
IL-36 alpha pathway
Inflammation
TSL-1502, a glucuronide prodrug of a poly (ADP-ribose) polymerase (PARP) inhibitor, exhibits potent anti-tumor activity in preclinical models
期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2021, 卷号: 11, 期号: 4, 页码: 1632-1645
作者:
Wang, Lei
;
Zhu, Xi
;
Li, Lili
;
Li, Lin
;
Fu, Li
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2021/06/11
PARP
DNA damage
hematologic toxicity
beta-glucuronidase
tumor selectivity
CST6 protein and peptides inhibit breast cancer bone metastasis by suppressing CTSB activity and osteoclastogenesis
期刊论文
THERANOSTICS, 2021, 卷号: 11, 期号: 20, 页码: 9821-9832
作者:
Li, Xiaoxun
;
Liang, Yajun
;
Lian, Cheng
;
Peng, Fangli
;
Xiao, Yansen
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/01/04
Breast cancer
Bone metastasis
Osteoclastogenesis
CST6
Peptide drug
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