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Palladium-mediated Suzuki-Miyaura Cross-Coupling Reaction of Potassium Boc-protected aminomethyltrifluoroborate with DNA-Conjugated aryl bromides for DNA-Encoded chemical library synthesis 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 卷号: 533, 期号: 2, 页码: 209-214
作者:  Qu, Yi;  Liu, Sixiu;  Wen, Huanan;  Xu, Yanfen;  An, Yulong
收藏  |  浏览/下载:68/0  |  提交时间:2020/12/24
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir 期刊论文
SCIENCE, 2020, 卷号: 368, 期号: 6498, 页码: 1499-+
作者:  Yin, Wanchao;  Mao, Chunyou;  Luan, Xiaodong;  Shen, Dan-Dan;  Shen, Qingya
收藏  |  浏览/下载:57/0  |  提交时间:2020/12/24
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文
MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15
作者:  Zhang, Tao;  Qu, Rong;  Chan, Shingpan;  Lai, Mengzhen;  Tong, Linjiang
收藏  |  浏览/下载:40/0  |  提交时间:2020/07/01
Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 4090-4106
作者:  Su, Haixia;  Zou, Yi;  Chen, Guofeng;  Dou, Huixia;  Xie, Hang
收藏  |  浏览/下载:32/0  |  提交时间:2020/07/01
Preclinical evaluation of 3D185, a novel potent inhibitor of FGFR1/2/3 and CSF-1R, in FGFR-dependent and macrophage-dominant cancer models. 期刊论文
CANCER IMMUNOLOGY RESEARCH, 2020, 卷号: 8, 期号: 3, 页码: 70-70
作者:  Dai, Yang;  Ji, Yichun;  Shen, Yanyan;  Su, Yi;  Liu, Bo
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/01
Metabolism-based structure optimization: Discovery of a potent and orally available tyrosine kinase ALK inhibitor bearing the tetracyclic benzo[b]carbazolone core (vol 26, pg 5399, 2016) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 4, 页码: 1
作者:  Han, Mei;  Wang, Chengyan;  Ji, Yinchun;  Song, Zilan;  Xing, Li
收藏  |  浏览/下载:7/0  |  提交时间:2020/07/01
Synthesis and in Vitro and in Vivo Biological Evaluation of Tissue-Specific Bisthiazole Histone Deacetylase (HDAC) Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 2, 页码: 804-815
作者:  Zhang, Shu-Wei;  Gong, Chao-Jun;  Su, Ming-Bo;  Chen, Fei;  He, Ting
收藏  |  浏览/下载:10/0  |  提交时间:2020/07/01


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