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上海药物研究所 [58]
厦门大学 [8]
复旦大学上海医学院 [7]
中国医学科学院 北京... [6]
昆明植物研究所 [5]
大连化学物理研究所 [4]
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期刊论文 [119]
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2019 [5]
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Anti-BACE1 and anti-AchE activities of undescribed spiro-dioxolane-containing meroterpenoids from the endophytic fungus Aspergillus terreus Thom
期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 165, 页码: 8
作者:
Qi, Changxing
;
Zhou, Qun
;
Gao, Weixi
;
Liu, Mengting
;
Chen, Chunmei
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2019/10/14
Aspergillus terreus Thom
endophytic fungus
3,5-Dimethylorsellinic acid-based meroterpenoid
Adducts
Alzheimer's disease
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury
期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
作者:
Hu, Dan-Dan
;
Zhao, Qi
;
Cheng, Yan
;
Xiao, Xue-Rong
;
Huang, Jian-Feng
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/03/26
liver injury
metabolomics
PPAR alpha
acylcarnitines
Tripterygium glycoside fraction n2: Alleviation of DSS-induced colitis by modulating immune homeostasis in mice
期刊论文
PHYTOMEDICINE, 2019, 卷号: 58, 页码: 12
作者:
Yang, Y. Q.
;
Wu, Y. F.
;
Xu, F. F.
;
Deng, J. B.
;
Wu, L. L.
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  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
Tripterygium wilfordii Hook F
Inflammatory bowel disease apoptosis
DSS
T lymphocytes
Modulation of Lipid Metabolism by Celastrol
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3, 页码: 1133-1144
作者:
Zhang, Ting
;
Zhao, Qi
;
Xiao, Xuerong
;
Yang, Rui
;
Hu, Dandan
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  |  
浏览/下载:76/0
  |  
提交时间:2019/04/15
celastrol
lipidomics
hyperlipidemia
LC-MS
Plasma miR-126 expression correlates with risk and severity of psoriasis and its high level at baseline predicts worse response to Tripterygium wilfordii Hook F in combination with acitretin
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 115
作者:
Jin, Waishu
;
Duan, Yanjuan
;
Zou, Jialing
;
Mao, Jingyi
;
Guo, Dongjie
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  |  
浏览/下载:35/0
  |  
提交时间:2019/12/05
Tripterygium wilfordii Hook F
Acitretin
miRNA-126
Plasma
Psoriasis
A sensitive LC-MS/MS method for the determination of triptolide and its application to pharmacokinetic research in rats
期刊论文
Biomedical chromatography : BMC, 2018, 页码: e4422
作者:
Xu, Ye
;
Chen, Xiaoyan
;
Zhong, Dafang
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  |  
浏览/下载:62/0
  |  
提交时间:2019/01/08
CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 8, 页码: 1386-1392
作者:
Xu, Ye
;
Zhang, Yi-fan
;
Chen, Xiao-yan
;
Zhong, Da-fang
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  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
triptolide
(5R)-5-hydroxytriptolide
CYP3A4
ritonavir
dexamethasone
pharmacokinetics
immunosuppressant
traditional Chinese medicine
Efficacy and safety of Tripterygium wilfordii hook F for chronic urticaria: a systematic review and meta-analysis
期刊论文
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2018, 卷号: 18
作者:
Liu, Liu
;
Zhao, Huaibo
;
Sun, Xiaoying
;
Zheng, Qi
;
Luo, Ying
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Chronic urticaria
Tripterygium wilfordii hook F
Tripterygium agents
Systematic review
Meta-analysis
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Efficacy and safety of Tripterygium wilfordii hook F for chronic urticaria: a systematic review and meta-analysis
期刊论文
BMC complementary and alternative medicine, 2018, 卷号: 18, 页码: 243
作者:
Liu Liu[1]
;
Zhao Huaibo[2]
;
Sun Xiaoying[3]
;
Zheng Qi[4]
;
Luo Ying[5]
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/04/22
Chronic urticaria
Meta-analysis
Systematic review
Tripterygium agents
Tripterygium wilfordii hook F
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