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北京大学 [7]
山东大学 [6]
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期刊论文 [52]
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Pharmacometabolomic prediction of individual differences of gastrointestinal toxicity complicating myelosuppression in rats induced by irinotecan.
期刊论文
Acta pharmaceutica Sinica. B, 2019, 卷号: No.1, 页码: 157-166
作者:
Yiqiao Gao
;
Wei Li
;
Jiaqing Chen
;
Xu Wang
;
Yingtong Lv
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/12/17
AUC-ROC,
area
under
receiver
operating
characteristic
BHB,
β-hydroxybutyric
acid
Biomarkers
C,
control
group
CA,
cholic
acid
CPT-11,
irinotecan
Complicating
toxicity
DBIL,
direct
bilirubin
DCA,
deoxycholic
acid
Diarrhea
FDR,
false
discovery
rate
GCA,
glycocholic
acid
Gastrointestinal
toxicity
IBIL,
indirect
bilirubin
IT-TOF/MS,
ion
trap/time-offlight
hybrid
mass
spectrometry
Individual
differences
Irinotecan
Lys,
lysine
MSTFA,
N-methyl-N-trifluoroacetamide
Metabolomics
NS,
non-sensitive
group
NSgt,
non-sensitive
for
gastrointestinal
toxicity
NSmt,
non-sensitive
for
myelosuppression
toxicity
OPLS-DA,
orthogonal
partial
least-squares-discriminant
analysis
PCA,
principal
component
analysis
PLS-DA,
partial
least-squares-discriminant
analysis
Phe,
phenylalanine
Prediction
QC,
quality
control
RSD,
relative
standard
deviation
S,
sensitive
group
Sgt,
sensitive
for
gastrointestinal
toxicity
Smt,
sensitive
for
myelosuppression
toxicity
T,
CPT-11
treated
group
Trp,
tryptophan
UFLC,
ultrafast
liquid
chromatography
VIP,
variable
importance
in
the
projection
pFDR,
false-discovery-rate-adjusted
P
value
USP9X-mediated deubiquitination of B-cell CLL/lymphoma 9 potentiates Wnt signaling and promotes breast carcinogenesis
期刊论文
2019, 卷号: 294, 期号: 25, 页码: 9844-9857
作者:
Shang, Zesen
;
Zhao, Jiao
;
Zhang, Qi
;
Cao, Cheng
;
Tian, Shanshan
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/01/03
deubiquitylation (deubiquitination)
breast cancer
cell signaling
carcinogenesis
Wnt pathway
B-cell CLL
lymphoma 9 (BCL9)
Lys-63-linked polyubiquitins
ubiquitin-specific peptidase 9
X-linked (USP9X)
Epigenetic regulation of cancer progression by EZH2: from biological insights to therapeutic potential
期刊论文
BIOMARKER RESEARCH, 2018, 卷号: 6
作者:
Gan, Lu
;
Yang, Yanan
;
Li, Qian
;
Feng, Yi
;
Liu, Tianshu
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
EZH2
Epigenetic
Histone H3 Lys27 trimethylation
Cancer
Polycomb repressive complex
NIR Fluorescent AzaBODIPY-Based Probe for the Specific Detection of L-Lysine
期刊论文
CHEMISTRYSELECT, 2018, 卷号: 3, 页码: 7581-7585
作者:
Jiang, Xin-Dong
;
Yue, Shuai
;
Jia, Lei
;
Li, Shuang
;
Li, Congling
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/02
azaBODIPY
NIR
fluorescent dye
probe
Lys
Modification of epsilon-poly-L-lysine in vivo to reduce self-toxicity and enhance antibiotic overproduction
期刊论文
AICHE JOURNAL, 2018, 卷号: 64, 期号: 12
作者:
Ding, Jin
;
Liang, Hengyu
;
Fu, Shuai
;
Liu, Ran
;
Deng, Zixin
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
Streptomyces albulus
epsilon-poly-L-lysine
2-epsilon-poly(L-lys)-glycerol
antibiotic
small-molecule residue modification
Aldehyde dehydrogenase 2 Glu504Lys variant predicts a worse prognosis of acute coronary syndrome patients
期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018, 卷号: 22, 期号: 4, 页码: 2518-2522
作者:
Pan, Chang
;
Zhao, Yu
;
Bian, Yuan
;
Shang, Rui
;
Wang, Jia-li
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
acute coronary syndrome
aldehyde dehydrogenase 2
Glu504Lys variant
prognosis
L-赖氨酸对鲢肌球蛋白热聚集行为的影响
期刊论文
食品科学, 2018, 卷号: 39, 期号: 08, 页码: 1-5
作者:
石彤[1]
;
袁丽[2]
;
王艳敏[3]
;
高瑞昌[4]
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/24
L-Lys
肌球蛋白
pH值
浊度
凝胶
氨基酸对花鲢肌球蛋白不同盐浓度下热聚集行为影响的研究
学位论文
: 江苏大学, 2018
作者:
王艳敏[1]
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/24
Glu
L-Cys
L-Lys
L-His
肌球蛋白
鱼糜
热聚集行为
凝胶特性
ALDH2 Glu504Lys Confers Susceptibility to Schizophrenia and Impacts Hippocampal-Prefrontal Functional Connectivity
期刊论文
CEREBRAL CORTEX, 2017, 卷号: 27, 期号: 3, 页码: 2034-2040
作者:
Zheng, Fanfan
;
Yan, Hao
;
Liu, Bing
;
Yue, Weihua
;
Fan, Lingzhong
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2016/10/17
Functional Connectivity
Glu504lys
Hippocampus
Pfc
Schizophrenia
Evaluation of Endoproteinase Lys- C/Trypsin Sequential Digestion Used in Proteomics Sample Preparation
期刊论文
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2017, 卷号: 45, 期号: 3, 页码: 316-321
作者:
Li Qian
;
Feng Yu
;
Tan Min-Jia
;
Zhai Lin-Hui
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
Trypsin
Lys-C
Sequential digestion
Proteomics
Liquid chromatography-tandem mass spectrometry
Missed cleavage
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