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浏览/检索结果: 共7条，第1-7条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 Discovery and development of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as Bcl-2/Mcl-1 inhibitors 期刊论文 BIOORGANIC CHEMISTRY, 2019, 卷号: 88 作者:  Liu, Renshuai;  Liu, Lulu;  Yang, Xinying;  Fang, Hao 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/11 1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid  Apoptosis  Bcl-2  Anti-tumor   Discovery and development of substituted tyrosine derivatives as Bcl-2/Mcl-1 inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 17, 页码: 4907-4915 作者:  Liu, Renshuai;  Liu, Lulu;  Liu, Tingting;  Yang, Xinying;  Wan, Yichao 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/11 Apoptosis  Bcl-2  Mcl-1  Tyrosine  Anti-tumor   A novel fluorinated thiosemicarbazone derivative-2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway 期刊论文 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 491, 期号: 1, 页码: 65-71 作者:  Zhao, Yue;  Guo, Chuanlong;  Wang, Lijun;  Wang, Shuaiyu;  Li, Xiangqian 收藏  |  浏览/下载：27/0  |  提交时间：2018/01/11 Thiosemicarbazone  Anticancer  2-(3  Apoptosis  4-difluorobenzylidene) Hydrazinecarbothioamide  Ros  Mitochondria-dependent Pathway   Design, synthesis and preliminary biological evaluation of indole-3-carboxylic acid-based skeleton of Bcl-2/Mcl-1 dual inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 6, 页码: 1939-1948 作者:  Liu, Tingting;  Wan, Yichao;  Liu, Renshuai;  Ma, Lin;  Li, Minyong 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/12 Bcl-2/Mcl-1  Indole-3-carboxylic acid-based derivatives  Anti-tumor  Inhibitors   Improved Antiproliferative Activities of a New Series of 1,3,4-Thiadiazole Derivatives Against Human Leukemia and Breast Cancer Cell Lines 期刊论文 高等学校化学研究, 2016, 卷号: 32, 期号: 5, 页码: 768-774 作者:  Liu Tingting;  Wan Yichao;  Liu Renshuai;  Ma Lin;  Li Minyong 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/16 Thiadiazole  Anti-tumor activity  Antiproliferative activity   Design and synthesis of a new generation of substituted purine hydroxamate analogs as histone deacetylase inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 7, 页码: 1446-1454 作者:  Liu, Renshuai;  Wang, Junhua;  Tang, Weiping;  Fang, Hao 收藏  |  浏览/下载：8/0  |  提交时间：2019/12/16 Purine  Histone deacetylase  Inhibitor  Anticancer   Enhancing the Sensitivity of Pharmacophore-Based Virtual Screening by Incorporating Customized ZBG Features: A Case Study Using Histone Deacetylase 8 期刊论文 Journal of chemical information and modeling, 2015, 卷号: 55, 期号: 4, 页码: 861-871 作者:  Hou, Xuben;  Du, Jintong;  Liu, Renshuai;  Zhou, Yi;  Li, Minyong 收藏  |  浏览/下载：5/0  |  提交时间：2019/12/17