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CORC

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Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:  Zhu, Kongkai;  Song, Jia-Li;  Tao, Hong-Rui;  Cheng, Zhi-Qiang;  Jiang, Cheng-Shi
收藏  |  浏览/下载：99/0  |  提交时间：2019/01/08
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/11
ETA as a novel Kv2.1 inhibitor ameliorates beta-cell dysfunction and hyperglycaemia 期刊论文
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2018, 卷号: 45, 期号: 12, 页码: 1257-1264
作者:  Zhou, Tingting;  Du, Mengfan;  Zhao, Tong;  Quan, Lingling;  Zhu, Zhiyuan
收藏  |  浏览/下载：94/0  |  提交时间：2019/01/08
Targeting Nrf2-mediated heme oxygenase-1 enhances non-thermal plasma-induced cell death in non-small-cell lung cancer A549 cells 期刊论文
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2018, 卷号: 658, 页码: 54-65
作者:  Ma, Jie;  Yu, K. N.;  Cheng, Cheng;  Ni, Guohua;  Shen, Jie
收藏  |  浏览/下载：51/0  |  提交时间：2019/01/11
MiR-155 affects osteosarcoma cell proliferation and invasion through regulating NF-kappa B signaling pathway 期刊论文
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2018, 卷号: 22, 期号: 22, 页码: 7633-7639
作者:  Lu, S.;  Liao, Q-S;  Tang, L.
收藏  |  浏览/下载：49/0  |  提交时间：2019/01/22
Cyclopeptide RA-V Inhibits Organ Enlargement and Tumorigenesis Induced by YAP Activation 期刊论文
CANCERS, 2018, 卷号: 10, 期号: 11
作者:  Ji, Xinyan;  Song, Lihua;  Sheng, Li;  Gao, Anhui;  Zhao, Yang
收藏  |  浏览/下载：76/0  |  提交时间：2019/01/08
Deletion of the fih gene encoding an inhibitor of hypoxia-inducible factors increases hypoxia tolerance in zebrafish 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 40, 页码: 15370-15380
作者:  Cai, Xiaolian;  Zhang, Dawei;  Wang, Jing;  Liu, Xing;  Ouyang, Gang
收藏  |  浏览/下载：58/0  |  提交时间：2019/07/02
Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Tang, Qing
收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08
Activated mitochondrial apoptosis in hESCs after dissociation involving the PKA/p-p53/Bax signaling pathway 期刊论文
EXPERIMENTAL CELL RESEARCH, 2018, 卷号: 369, 期号: 2, 页码: 226-233
作者:  Zhang, Liang;  Ma, Liang;  Yan, Tingxuan;  Han, Xinya;  Xu, Jiandong
收藏  |  浏览/下载：36/0  |  提交时间：2018/10/11
Cognitive Impairment and Endoplasmic Reticulum Stress Induced by Repeated Short-Term Sevoflurane Exposure in Early Life of Rats 期刊论文
FRONTIERS IN PSYCHIATRY, 2018, 卷号: 9
作者:  Shen, Fu-Yi;  Song, Ying-Cai;  Guo, Fei;  Xu, Zhen-Dong;  Li, Qian
收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08

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