CORC

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CORC

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Optimization of P2Y(12) Antagonist Ethyl 6-(4-((Benzylsulfonyl)carbarnoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate (AZD1283) Led to the Discovery of an Oral Antiplatelet Agent with Improved Druglike Properties 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 3088-3106
作者:  Kong, Deyu;  Xue, Tao;  Guo, Bin;  Cheng, Jianjun;  Liu, Shunyin
收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01
Clopidogrel as a donor probe and thioenol derivatives as flexible promoieties for enabling H2S biomedicine 期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9
作者:  Zhu, Yaoqiu;  Romero, Elkin L.;  Ren, Xiaodong;  Sanda, Angel J.;  Du, Congkuo
收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08
A novel photocleavable heparin derivative with light controllable anticoagulant activity 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 184, 页码: 191-198
作者:  Sun, Feifei;  Liu, Yinyin;  Wang, Dongdong;  Wang, Zhaojie;  Mu, Haibo
收藏  |  浏览/下载：40/0  |  提交时间：2019/01/08
Platelets Express Activated P2Y(12) Receptor in Patients With Diabetes Mellitus 期刊论文
CIRCULATION, 2017, 卷号: 136, 期号: 9, 页码: 817-U102
作者:  Hu, Liang;  Chang, Lin;  Zhang, Yan;  Zhai, Lili;  Zhang, Shenghui
收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08
Modeling ligand recognition at the P2Y(12) receptor in light of X-ray structural information 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2015, 卷号: 29, 期号: 8, 页码: 737-756
作者:  Paoletta, Silvia;  Sabbadin, Davide;  von Kuegelgen, Ivar;  Hinz, Sonja;  Katritch, Vsevolod
收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08
Two disparate ligand-binding sites in the human P2Y(1) receptor 期刊论文
NATURE, 2015, 卷号: 520, 期号: 7547, 页码: 317-+
作者:  Zhang, Dandan;  Gao, Zhan-Guo;  Zhang, Kaihua;  Kiselev, Evgeny;  Crane, Steven
收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08
Design, Synthesis, and Structure-Activity and Structure-Pharmacokinetic Relationship Studies of Novel [6,6,5] Tricyclic Fused Oxazolidinones Leading to the Discovery of a Potent, Selective, and Orally Bioavailable FXa Inhibitor 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 57, 期号: 18, 页码: 7770-7791
作者:  Xue, Tao;  Ding, Shi;  Guo, Bin;  Zhou, Yuren;  Sun, Peng
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08
Structure of the human P2Y(12) receptor in complex with an antithrombotic drug 期刊论文
NATURE, 2014, 卷号: 509, 期号: 7498, 页码: 115-118
作者:  Zhang, Kaihua;  Zhang, Jin;  Gao, Zhan-Guo;  Zhang, Dandan;  Zhu, Lan
收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08
Advances in the structure-activity relationship study of natural flavonoids and its derivatives 期刊论文
Acta Pharmaceutica Sinica, 2011, 卷号: 46, 期号: 6, 页码: 622-630
作者:  ZHONG Jianqing;  LI Bo;  JIA Qi;  LI Yiming;  ZHU Weiliang
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08

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