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科研机构
江苏大学 [6]
大连理工大学 [5]
中国医学科学院 北京... [3]
山东大学 [2]
暨南大学 [2]
深圳先进技术研究院 [1]
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内容类型
期刊论文 [24]
会议论文 [3]
学位论文 [1]
发表日期
2018 [28]
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发表日期:2018
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Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:
Liu, Xuesong
;
Wang, Beilei
;
Chen, Cheng
;
Jiang, Zongru
;
Hu, Chen
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/11
ABL kinase
Kinase inhibitor
ABL mutant
CML
Slab-triggered wet upwellings produce large volumes of melt: Insights into the destruction of the North China Craton
期刊论文
TECTONOPHYSICS, 2018, 卷号: 746, 页码: 266-279
作者:
Yang, Jianfeng
;
Zhao, Liang
;
Kaus, Boris J. P.
;
Lu, Gang
;
Wang, Kun
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2019/03/04
Numerical modeling
Craton destruction
Lithosphere thinning
Intraplate volcanism
Dehydration
北京地区畜禽养殖场周边蔬菜地生食蔬菜抗生素耐药基因(ARGs)的赋存特性
期刊论文
环境化学, 2018, 卷号: 37, 期号: 04, 页码: 625-635
作者:
陈倩
;
魏源送
;
李娟
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/03/14
畜禽养殖场
生食蔬菜
抗生素耐药基因
赋存特性
Investigation of a minor groove-binding polyamide targeted to E2F1 transcription factor in chronic myeloid leukaemia (CML) cells.
期刊论文
BLOOD CELLS MOLECULES AND DISEASES, 2018
作者:
Holyoake, Tessa L.
;
Hayatigolkhatmi, Kourosh
;
Pellicano, Francesca
;
Burley, Glenn A.
;
jackson, Lorna
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/31
Comparison of Frequency and Sensitivity of BCR-ABL1 Kinase Domain Mutations in Asian and White Patients With Imatinib-resistant Chronice-Phase Chronic Myeloid Leukemia
期刊论文
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2018, 卷号: 18, 期号: 10
作者:
Cui, Jiu Wei
;
Kim, Hawk
;
Kim, SooHyun
;
Kim, Hyeoung-Joon
;
Kim, Yeo-Kyeoung
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/05
Asian countries
BCR-ABL1 mutation
CML
Drug resistance
Imatinib
A New Image Encryption Algorithm Based on CML and DNA Seqauence
期刊论文
IEEE ACCESS, 2018, 卷号: 6, 页码: 62272-62285
作者:
Wang, Xingyuan
;
Hou, Yutao
;
Wang, Shibing
;
Li, Rui
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/02
Chaos
encryption
gray-scale
image processing
DNA sequence
CML system
Spatiotemporal Chaos in Coupled Logistic Map Lattice With Dynamic Coupling Coefficient and Its Application in Image Encryption
期刊论文
IEEE ACCESS, 2018, 卷号: 6, 页码: 39705-39724
作者:
Wang Xingyuan
;
Feng Le
;
Wang Shibing
;
Chuan Zhang
;
Zhang Yingqian
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/02
Logistic-dynamic
CML
parameter space
dynamic coupling
image encryption
DFT/TDDFT insights into effects of dissociation and metal complexation on photochemical behavior of enrofloxacin in water
期刊论文
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2018, 卷号: 25, 页码: 30609-30616
作者:
Wang, Se
;
Wang, Zhuang
;
Hao, Ce
;
Peijnenburg, Willie J. G. M.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/02
Enrofloxacin
Dissociated species
Photochemical behavior
DFT
Combined pollution
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Color image DNA encryption using NCA map-based CML and one-time keys
期刊论文
SIGNAL PROCESSING, 2018, 卷号: 148, 页码: 272-287
作者:
Wu, Xiangjun
;
Wang, Kunshu
;
Wang, Xingyuan
;
Kan, Haibin
;
Kurths, Juergen
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/02
Color image encryption
SHA-256
NCA map-based CML
DNA sequence operation
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