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上海药物研究所 [26]
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期刊论文 [40]
发表日期
2020 [40]
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Modulation of the G-Protein-Coupled Receptor 84 (GPR84) by Agonists and Antagonists
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 24, 页码: 15399-15409
作者:
Chen, Lin-Hai
;
Zhang, Qing
;
Xie, Xin
;
Nan, Fa-Jun
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2021/05/24
Targeted Drugs for Treatment of Pulmonary Arterial Hypertension: Past, Present, and Future Perspectives
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 24, 页码: 15153-15186
作者:
Zheng, Wei
;
Wang, Zhen
;
Jiang, Xiangrui
;
Zhao, Qingjie
;
Shen, Jingshan
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  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
Targeted Proteomics Combined with Affinity Mass Spectrometry Analysis Reveals Antagonist E7 Acts As an Intracellular Covalent Ligand of Orphan Receptor GPR52
期刊论文
ACS CHEMICAL BIOLOGY, 2020, 卷号: 15, 期号: 12, 页码: 3275-3284
作者:
Ma, Mengna
;
Guo, Shimeng
;
Lin, Xi
;
Li, Shanshan
;
Wu, Yiran
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/05/24
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yu, Ming-cheng
;
Yang, Feng
;
Ding, Xiao-yu
;
Sun, Nan-nan
;
Jiang, Zheng-yuan
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2020/12/24
RORγ
t
cocrystal structures
MD simulation
“
short”
inverse agonists
agonists
“
long”
inverse agonists
Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 21, 页码: 12748-12772
作者:
Li, Junyou
;
Liu, Mengqi
;
Li, Yazhou
;
Sun, Dan-dan
;
Shu, Zhihao
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  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
TCDD-induced antagonism of MEHP-mediated migration and invasion partly involves aryl hydrocarbon receptor in MCF7 breast cancer cells
期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2020, 卷号: 398, 页码: 1-10
作者:
Shan, Anqi
;
Leng, Ling
;
Li, Jing
;
Luo, Xiu-mei
;
Fan, Ya-jiao
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/09/14
Coexposure
Antagonism
AhR
Migration
Invasion
A projection from the paraventricular nucleus of the thalamus to the shell of the nucleus accumbens contributes to footshock stress-induced social avoidance
期刊论文
NEUROBIOLOGY OF STRESS, 2020, 卷号: 13, 页码: 13
作者:
Dong, Xinwen
;
Li, Sa
;
Kirouac, Gilbert J.
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  |  
浏览/下载:19/0
  |  
提交时间:2021/03/08
Social anxiety
Paraventricular nucleus of the thalamus
Nucleus accumbens
Dynorphin
Social avoidance
Evaluation of biased agonism mediated by dual agonists of the GLP-1 and glucagon receptors
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 180, 页码: 16
作者:
Darbalaei, Sanaz
;
Yuliantie, Elita
;
Dai, Antao
;
Chang, Rulue
;
Zhao, Peishen
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  |  
浏览/下载:18/0
  |  
提交时间:2020/12/21
G protein-coupled receptor
Glucagon-like peptide-1 receptor
Glucagon receptor
Biased agonism
Unimolecular dual agonist
Heat-killedSalmonellaTyphimurium protects mice against carbon ion radiation
期刊论文
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2020, 卷号: 48, 期号: 10, 页码: 12
作者:
Liao, Zebin
;
Liu, Zhe
;
Gong, Zhenyu
;
Hu, Xuguang
;
Chen, Yuanyuan
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/15
Carbon ion radiation
heat-killedSalmonellaTyphimurium
radioprotector
apoptosis
IRF3
7
Toll-like receptors
Structural insights into the activation of GLP-1R by a small molecule agonist
期刊论文
CELL RESEARCH, 2020, 页码: 3
作者:
Ma, Honglei
;
Huang, Wei
;
Wang, Xiaoxi
;
Zhao, Lihua
;
Jiang, Yi
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/12/24
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