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浏览/检索结果: 共8条，第1-8条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 32, 页码: 8 作者:  Wang, Xi;  Cheng, Xi;  Zhao, Lihua;  Wang, Yuzhe;  Ye, Chenyu 收藏  |  浏览/下载：23/0  |  提交时间：2021/11/04 parathyroid hormone receptor 2  cryo-electron microscopy  G protein-coupled receptor  ligand recognition  syndromic short stature   Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening 期刊论文 BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14 作者:  Zhou, Qingtong;  Guo, Wanjing;  Dai, Antao;  Cai, Xiaoqing;  Vass, Marton 收藏  |  浏览/下载：40/0  |  提交时间：2021/08/17 GLP-1R  virtual screening  allosteric modulator  drug discovery  molecular docking   A molecular switch regulating transcriptional repression and activation of PPAR gamma 期刊论文 NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 14 作者:  Shang, Jinsai;  Mosure, Sarah A.;  Zheng, Jie;  Brust, Richard;  Bass, Jared 收藏  |  浏览/下载：21/0  |  提交时间：2020/12/24 Revealing the Positive Binding Cooperativity Mechanism between the Orthosteric and the Allosteric Antagonists of CCR2 by Metadynamics and Gaussian Accelerated Molecular Dynamics Simulations 期刊论文 ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 4, 页码: 628-637 作者:  An, Xiaoli;  Bai, Qifeng;  Bing, Zhitong;  Liu, Hongli;  Zhang, Qianqian 收藏  |  浏览/下载：21/0  |  提交时间：2022/01/18 CC chemokine receptor 2  orthosteric antagonist  allosteric antagonist  binding cooperativity  metadynamics simulation  Gaussian accelerated MD simulation   High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening 期刊论文 CHEMICAL SCIENCE, 2018, 卷号: 9, 期号: 12, 页码: 3192-3199 作者:  Qin, Shanshan;  Meng, Mengmeng;  Yang, Dehua;  Bai, Wenwen 收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08 Solvent-accessibility of discrete residue positions in the polypeptide hormone glucagon by F-19-NMR observation of 4-fluorophenylalanine 期刊论文 JOURNAL OF BIOMOLECULAR NMR, 2017, 卷号: 68, 期号: 1, 页码: 1-6 作者:  Hou, Yaguang;  Hu, Wanhui;  Li, Xiaona;  Skinner, John J.;  Liu, Dongsheng 收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 F-19-NMR  Glucagon  F-19 chemical shift  Solvent exposure from D2O effects   Allosteric modulation of sigma-1 receptors elicits anti-seizure activities 期刊论文 BRITISH JOURNAL OF PHARMACOLOGY, 2015, 卷号: 172, 期号: 16, 页码: 4052-4065 作者:  Guo, Lin;  Chen, Yanke;  Zhao, Rui;  Wang, Guanghui;  Friedman, Eitan 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 Two disparate ligand-binding sites in the human P2Y(1) receptor 期刊论文 NATURE, 2015, 卷号: 520, 期号: 7547, 页码: 317-+ 作者:  Zhang, Dandan;  Gao, Zhan-Guo;  Zhang, Kaihua;  Kiselev, Evgeny;  Crane, Steven 收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08