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Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening 期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14
作者:  Zhou, Qingtong;  Guo, Wanjing;  Dai, Antao;  Cai, Xiaoqing;  Vass, Marton
收藏  |  浏览/下载:38/0  |  提交时间:2021/08/17
Structures of G(i)-bound metabotropic glutamate receptors mGlu2 and mGlu4 期刊论文
NATURE, 2021, 卷号: 594, 期号: 7864, 页码: 583-+
作者:  Lin, Shuling;  Han, Shuo;  Cai, Xiaoqing;  Tan, Qiuxiang;  Zhou, Kexiu
收藏  |  浏览/下载:34/0  |  提交时间:2021/11/16
Structures of human mGlu2 and mGlu7 homo- and heterodimers 期刊论文
NATURE, 2021, 卷号: 594, 期号: 7864, 页码: 589-+
作者:  Du, Juan;  Wang, Dejian;  Fan, Hongcheng;  Xu, Chanjuan;  Tai, Linhua
收藏  |  浏览/下载:23/0  |  提交时间:2021/08/17
Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11
作者:  Cong, Zhaotong;  Chen, Li-Nan;  Ma, Honglei;  Zhou, Qingtong;  Zou, Xinyu
收藏  |  浏览/下载:42/0  |  提交时间:2021/08/17
Affinity Mass Spectrometry-Based Fragment Screening Identified a New Negative Allosteric Modulator of the Adenosine A(2A) Receptor Targeting the Sodium Ion Pocket 期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 6, 页码: 991-1002
作者:  Lu, Yan;  Liu, Hongyue;  Yang, Dehua;  Zhong, Li;  Xin, Ye
收藏  |  浏览/下载:25/0  |  提交时间:2021/08/17
Structures of Gi-bound metabotropic glutamate receptors mGlu2 and mGlu4 期刊论文
NATURE, 2021, 页码: 23
作者:  Lin, Shuling;  Han, Shuo;  Cai, Xiaoqing;  Tan, Qiuxiang;  Zhou, Kexiu
收藏  |  浏览/下载:22/0  |  提交时间:2021/08/17
Recent advances in dopaminergic strategies for the treatment of Parkinson's disease 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:  Mao, Qi;  Qin, Wang-zhi;  Zhang, Ao;  Ye, Na
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/01
Identification and structural insight of an effective PPAR gamma modulator with improved therapeutic index for anti-diabetic drug discovery 期刊论文
CHEMICAL SCIENCE, 2020, 卷号: 11, 期号: 8, 页码: 2260-2268
作者:  Jiang, Haowen;  Zhou, X. Edward;  Shi, Jingjing;  Zhou, Zhi;  Zhao, Guanguan
收藏  |  浏览/下载:24/0  |  提交时间:2020/07/01
recentadvancesindopaminergicstrategiesforthetreatmentofparkinsonsdisease 期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 4, 页码: 471
作者:  Mao Qi;  Qin Wangzhi;  Zhang Ao;  Ye Na
收藏  |  浏览/下载:19/0  |  提交时间:2020/07/01
Molecular Basis of Action of a Small-Molecule Positive Allosteric Modulator Agonist at the Type 1 Cholecystokinin Holoreceptor 期刊论文
MOLECULAR PHARMACOLOGY, 2019, 卷号: 95, 期号: 3
作者:  Desai, Aditya J.;  Mechin, Ingrid;  Nagarajan, Karthigeyan;  Valant, Celine;  Wootten, Denise
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/05


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