CORC

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CORC

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Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists 期刊论文
PHARMACEUTICALS, 2022, 卷号: 15
作者:  Sun, Lei;  Zheng, Zhi-Ming;  Shao, Chang-Sheng;  Zhang, Zhi-Yong;  Li, Ming-Wei
收藏  |  浏览/下载：15/0  |  提交时间：2022/12/22
Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Li, Teng-teng;  Peng, Cheng;  Wang, Ji-qiu;  Xu, Zhi-jian;  Su, Ming-bo
收藏  |  浏览/下载：39/0  |  提交时间：2022/01/18
Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site 期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 11, 页码: 2444-2452
作者:  Wang, Jiang;  Yang, Dehua;  Cheng, Xi;  Yang, Linlin;  Wang, Zhaohui
收藏  |  浏览/下载：23/0  |  提交时间：2022/01/04
Signaling profiles in HEK 293T cells co-expressing GLP-1 and GIP receptors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 8
作者:  Wang, Yu-zhe;  Yang, De-hua;  Wang, Ming-wei
收藏  |  浏览/下载：18/0  |  提交时间：2021/11/04
Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening 期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14
作者:  Zhou, Qingtong;  Guo, Wanjing;  Dai, Antao;  Cai, Xiaoqing;  Vass, Marton
收藏  |  浏览/下载：39/0  |  提交时间：2021/08/17
Intestinal MYC modulates obesity-related metabolic dysfunction 期刊论文
NATURE METABOLISM, 2021, 页码: 37
作者:  Luo, Yuhong;  Yang, Shoumei;  Wu, Xuan;  Takahashi, Shogo;  Sun, Lulu
收藏  |  浏览/下载：27/0  |  提交时间：2021/08/17
Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11
作者:  Cong, Zhaotong;  Chen, Li-Nan;  Ma, Honglei;  Zhou, Qingtong;  Zou, Xinyu
收藏  |  浏览/下载：44/0  |  提交时间：2021/08/17
A novel GPR120-selective agonist promotes insulin secretion and improves chronic inflammation 期刊论文
LIFE SCIENCES, 2021, 卷号: 269, 页码: 8
作者:  Yang, Liu;  Lei, Xian-Tao;  Huang, Qi;  Wang, Ting;  Sun, Hong-Bin
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
Secretion of glucagon-like peptide-1 induced by Cynanchum pregnane derivatives: Preliminary hypotheses regarding key structural elements 期刊论文
PHYTOCHEMISTRY LETTERS, 2021, 卷号: 41, 页码: 88-91
作者:  Huguet, Clement;  Real, Eleonore;  Zhao, Wei-Min;  Urbain, Aurelie
收藏  |  浏览/下载：11/0  |  提交时间：2021/11/04
G protein-coupled receptors: structure- and function-based drug discovery 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 27
作者:  Yang, Dehua;  Zhou, Qingtong;  Labroska, Viktorija;  Qin, Shanshan;  Darbalaei, Sanaz
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24

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