CORC

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CORC

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Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:  Liu, Xiaohua;  Zhang, Yu;  Li, Yalei;  Wang, Juan;  Ding, Huaqian
收藏  |  浏览/下载：29/0  |  提交时间：2021/05/24
USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines 期刊论文
FEBS JOURNAL, 2020, 页码: 18
作者:  Wang, Hui;  Meng, Qian;  Ding, Yiluan;  Xiong, Muya;  Zhu, Mengying
收藏  |  浏览/下载：84/0  |  提交时间：2020/12/24
Design, synthesis and biological evaluation of deuterated Vismodegib for improving pharmacokinetic properties 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 页码: 2399-2402
作者:  Wang, Fangying;  Jiang, Hongxia;  Deng, Yufang;  Yu, Jiang;  Zhan, Miao
收藏  |  浏览/下载：2/0  |  提交时间：2019/11/26
Strategies to target the Hedgehog signaling pathway for cancer therapy 期刊论文
MEDICINAL RESEARCH REVIEWS, 2018, 卷号: 38, 页码: 870-913
作者:  Xin, Minhang;  Ji, Xinyue;  De La Cruz, Ladie Kimberly;  Thareja, Suresh;  Wang, Binghe
收藏  |  浏览/下载：5/0  |  提交时间：2019/11/26
Design, synthesis and biological evaluation of deuterated Vismodegib for improving pharmacokinetic properties 期刊论文
Bioorganic and Medicinal Chemistry Letters, 2018
作者:  Fangying Wang;  Hongxia Jiang;  Yufang Deng;  Jiang Yu;  Miao Zhan
收藏  |  浏览/下载：8/0  |  提交时间：2019/02/25
Discovery of Novel Macrocyclic Hedgehog Pathway Inhibitors Acting by Suppressing the Gli-Mediated Transcription 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 19, 页码: 8218-8245
作者:  Liu, Gang;  Huang, Wenjing;  Wang, Juan;  Liu, Xiaohua;  Yang, Jun
收藏  |  浏览/下载：11/0  |  提交时间：2019/01/08
A structurally guided dissection-then-evolution strategy for ligand optimization of smoothened receptor 期刊论文
MEDCHEMCOMM, 2017, 卷号: 8, 期号: 6, 页码: 1332-1336
作者:  Ye, Lintao;  Ding, Kang;  Zhao, Fei;  Liu, Xiaoyan;  Wu, Yiran
收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08
A novel therapeutic approach against B-cell non-Hodgkin's lymphoma through co-inhibition of Hedgehog signaling pathway and autophagy 期刊论文
TUMOR BIOLOGY, 2016, 卷号: 37, 期号: 6
作者:  Fan, Jiajun;  Zeng, Xian;  Li, Yubin;  Wang, Shaofei;  Yang, Ping
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/05
Synthesis and antiproliferative activity of novel 4-substituted-phenoxy-benzamide derivatives 期刊论文
CHINESE CHEMICAL LETTERS, 2015, 卷号: 26, 期号: 10, 页码: 1307-1310
作者:  Sun ChiYu;  Li YangSheng;  Shi AiLong;  Li YaFei;  Cao RuiFang
收藏  |  浏览/下载：6/0  |  提交时间：2021/02/02
Synthesis and antiproliferative activity of novel 4-substituted-phenoxy-benzamide derivatives 期刊论文
CHINESE CHEMICAL LETTERS, 2015, 卷号: 26, 期号: 10, 页码: 1307-1310
作者:  Sun ChiYu;  Li YangSheng;  Shi AiLong;  Li YaFei;  Cao RuiFang
收藏  |  浏览/下载：2/0  |  提交时间：2021/02/02

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