CORC

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CORC

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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia
收藏  |  浏览/下载：3/0  |  提交时间：2024/04/07
Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/01
Allosteric Inhibitors of SHP2: An Updated Patent Review (2015-2020) 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2021, 卷号: 28, 期号: 19, 页码: 3825-3842
作者:  Wu, Jingwei;  Zhang, Huan;  Zhao, Guilong;  Wang, Runling
收藏  |  浏览/下载：65/0  |  提交时间：2021/08/17
Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5
作者:  Satheeshkumar, Rajendran;  Zhu, Rui;  Feng, Bo;  Huang, Chao;  Gao, Ya
收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01
SHP2 inhibitor PHPS1 protects against atherosclerosis by inhibiting smooth muscle cell proliferation 期刊论文
BMC CARDIOVASCULAR DISORDERS, 2018, 卷号: 18
作者:  Cao, Zhiyong;  Chen, Jia;  Guan, Jingshu
收藏  |  浏览/下载：7/0  |  提交时间：2019/12/05
Synthesis and antitumor activity of novel phenylhydrazonopyrazolone derivatives and molecular dynamics simulations 期刊论文
RESEARCH ON CHEMICAL INTERMEDIATES, 2018, 卷号: 44, 期号: 9
作者:  Hu, Xia-min;  Cui, Zhi-wen;  Dong, Wei;  Zhu, Yue;  Gao, Cheng-zhi
收藏  |  浏览/下载：7/0  |  提交时间：2019/12/06
Dietary quercetin potentiates the antiproliferative effect of interferon-alpha in hepatocellular carcinoma cells through activation of JAK/STAT pathway signaling by inhibition of SHP2 phosphatase 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 69, 页码: 113734-113748
作者:  Igbe, I;  Shen, XF;  Jiao, W;  Qiang, Z;  Deng, T
收藏  |  浏览/下载：58/0  |  提交时间：2018/08/28
Quercetin  Interferon  Shp2  Jak  Stat  
Plasiatine, an Unprecedented Indole-Phenylpropanoid Hybrid from Plantago asiatica as a Potent Activator of the Nonreceptor Protein Tyrosine Phosphatase Shp2 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 期号: 1, 页码: 24945
作者:  Gao, Zhong-Hua;  Shi, Yi-Ming;  Qiang, Zhe;  Wang, Xia;  Shang, Shan-Zhai
收藏  |  浏览/下载：78/0  |  提交时间：2016/08/22
Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 3, 页码: 778-781
作者:  Zhang, Li;  Jiang, Cheng-Shi;  Gao, Li-Xin;  Gong, Jing-Xu;  Wang, Zhong-Hua
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08
Design, synthesis and evaluation of novel F-19 magnetic resonance sensitive protein tyrosine phosphatase inhibitors 期刊论文
MEDCHEMCOMM, 2016, 卷号: 7, 期号: 8, 页码: 1672-1680
作者:  Li, Yu;  Xia, Guiquan;  Guo, Qi;  Wu, Li;  Chen, Shizhen
收藏  |  浏览/下载：26/0  |  提交时间：2016/11/04

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