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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Paralichthys olivaceus
MLKL-mediated necroptosis is activated by RIPK1/3 and involved in anti-microbial immunity
期刊论文
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 15, 页码: 11
作者:
Hao, Kangwei
;
Xu, Hang
;
Jiang, Shuai
;
Sun, Li
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/04/07
Paralichthys olivaceus
necroptosis
RIPK1
RIPK3
MLKL
immune defense
Discovery of Pyrrolo[2,3-d]pyrimidine derivatives as potent and selective colony stimulating factor 1 receptor kinase inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243
作者:
Liang, Xiaofei
;
Wang, Chun
;
Wang, Beilei
;
Liu, Juan
;
Qi, Shuang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/12/23
CSF1R inhibitor
Kinase inhibitor
Macrophage polarization
Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis
期刊论文
BIOACTIVE MATERIALS, 2022, 卷号: 17, 页码: 406-424
作者:
Wang, Jin
;
Xie, Si-an
;
Li, Ning
;
Zhang, Tao
;
Yao, Weijuan
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  |  
浏览/下载:105/0
  |  
提交时间:2022/06/10
Matrix stiffness
Inflammation
DDR1
DNMT1
Mechanotransduction
Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Wang, Zuo-wei
;
Zou, Feng-ming
;
Wang, Ao-li
;
Yang, Jing
;
Jin, Rui
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  |  
浏览/下载:17/0
  |  
提交时间:2022/12/22
AZD4547
RIPK1
inhibitors
SIRS model
anti-necroptosis
Arabidopsis ERdj3B coordinates with ERECTA-family receptor kinases to regulate ovule development and the heat stress response
期刊论文
PLANT CELL, 2022, 卷号: 34, 期号: 10, 页码: 3665-3684
作者:
Leng, Ya-Jun
;
Yao, Ya-Sen
;
Yang, Ke-Zhen
;
Wu, Pei-Xiang
;
Xia, Yu-Xin
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  |  
浏览/下载:0/0
  |  
提交时间:2024/03/07
CLE peptides: critical regulators for stem cell maintenance in plants
期刊论文
PLANTA, 2022, 卷号: 255, 期号: 1
作者:
Song, Xiu-Fen
;
Hou, Xiu-Li
;
Liu, Chun-Ming
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  |  
浏览/下载:0/0
  |  
提交时间:2024/03/07
CLE peptides
Ligands
Procambium
Receptor kinases
Root apical meristem
Shoot apical meristem
Identification of leucine-rich repeat receptor-like protein kinase (LRR-RLK) genes in paper mulberry and their potential roles in response to cold stress
期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2022, 卷号: 97
作者:
Su, Yalei
;
Peng, Xianjun
;
Shen, Shihua
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  |  
浏览/下载:0/0
  |  
提交时间:2024/03/07
Paper mulberry
Leucine-rich repeat receptor -like protein kinase
Expression profile analysis
Cold stress
Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Dong, Ying
;
Tang, Bi-xi
;
Wang, Qi
;
Zhou, Li-wei
;
Li, Cong
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2022/01/04
idiopathic pulmonary fibrosis
DDRs
kinase inhibitor
indazole derivatives
XBLJ-13
nintedanib
bleomycin-induced pulmonary fibrosismouse model
The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:
Jiang, Yuchen
;
Peng, Xia
;
Ji, Yinchun
;
Dai, Yang
;
Fang, Yanfen
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/12/16
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