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Broad targeting of triptolide to resistance and sensitization for cancer therapy 期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:  Hou, Zhen-yan;  Tong, Xiao-pei;  Peng, Yong-bo;  Zhang, Bi-Kui*;  Yan, Miao*
收藏  |  浏览/下载:48/0  |  提交时间:2019/12/03
ABC  ATP-binding cassette  AKT  V-Akt murine thymoma viral oncogene homolog  ALDH1  aldehyde dehydrogenase 1  AR  androgen receptor  Bad  Bcl-2-associated death promoter  Bak  Bcl-2 homologous antagonist killer  Bax  Bcl-2-associated X protein  Bcl-2  B-cell lymphoma  Bcl-xL  Bcl-extra large  Bcl-xs  Bcl-extra short  BCRP  breast cancer resistance protein  Bid  BH3 interacting domain death agonist  Bik  Bcl-2-interacting killer  BNIP3  Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3  CAF  cancer-associated fibroblast  CAIX  carbonic anhydrase IX  cFLIP  cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein  ChIP  chromatin immunoprecipitation  CI  Combination Index  cIAP1/2  cellular IAP1/2  CML  chronic myelogenous leukemia  CSC  cancer stem cell  DISC  death-inducing signaling complex  DR  death receptor  DRI  Dose Reduction Index  ECM  extracellular matrix  EMT  epithelial-mesenchymal transition  EpCAM  epithelial cell adhesion molecule  GLUT  glucose transporter  GSK3β  glycogen synthase kinase-3β  HIF-1  hypoxia inducible factor-1  HSF1  heat shock factor 1  HSP  heat shock protein  IAP  inhibitor of apoptosis protein  JNK  c-JUN N-terminal kinase  MAPK  mitogen-activated protein kinase  Mcl-1  myeloid leukemia cell differentiation protein  MDM2  murine double minute 2  MDR  multidrug resistance  MKP  MAPK phosphatase  MRP1  multidrug resistance protein 1  NF-κB  nuclear factor-kappaB  pAkt  phosphor-Akt  PARP  poly ADP-ribose polymerase  P-gp  P-glycoprotein  PI3K-PTEN  phosphatidylinositol 3-kinase-phosphatase and tensin homolog  PKC  phosphorylated at Ser9 by protein kinase C  pp2A  protein phosphatase 2A  REST  repressor element-1 silencing transcription factor  SAR  structure-activity relationship  TAM  tumor-associated macrophage  TFIIH  transcription factor IIH  TKI  tyrosine kinase inhibitor  TM  tumor-microenvironment  TRAIL/Apo-2L  TNF-related apoptosis-inducing ligand  tRXRα  the N-terminal truncated form of the nuclear retinoid X receptor-α  TWHF  Tripterygium wilfordii Hook F  VEGF  vascular endothelial growth factor  XIAP  X-linked IAP  XPB  xerodermapigmentosum group B protein  Triptolide  Antineoplastic  Resistance  Sensitization  Mechanism  
Prion protein is required for tumor necrosis factor (tnf)-triggered nuclear factor b (nf-b) signaling and cytokine production 期刊论文
Journal of biological chemistry, 2017, 卷号: 292, 期号: 46, 页码: 18747-18759
作者:  Wu, Gui-Ru;  Mu, Tian-Chen;  Gao, Zhen-Xing;  Wang, Jun;  Sy, Man-Sun
收藏  |  浏览/下载:61/0  |  提交时间:2019/05/08
TXNIP/TRX/NF-kappa B and MAPK/NF-kappa B pathways involved in the cardiotoxicity induced by Venenum Bufonis in rats 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:  Bi, Qi-rui;  Hou, Jin-jun;  Qi, Peng;  Ma, Chun-hua;  Feng, Rui-hong
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
Renoprotective approaches and strategies in acute kidney injury 期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 163, 页码: 58-73
作者:  Yang, Yuan;  Song, Meifang;  Liu, Yu;  Liu, Hong;  Sun, Lin
收藏  |  浏览/下载:20/0  |  提交时间:2019/12/03
ACTH  Adrenocorticotropic hormone  AIF  Apoptosis inducing factor  AKI  Acute kidney injury  BMSC  Bone marrow derived stem cells  CIN  Contrast-induced nephropathy  COMP-Ang1  Cartilage oligomeric matrix protein-angiopoietin-1  CysLT1R  Cysteinyl leukotriene-1 receptor  DMARD  Disease-modifying antirheumatic drugs  eNOS  Endothelial nitric oxide synthase  eEPCs  Endothelial progenitor cells  HDAC  Histone deacetylase  HSPC  Hematopoietic stem and progenitor cells  IRI  Ischemia–reperfusion injury  ICAM-1  Intercellular adhesion molecule-1  JNK  c-Jun N-terminal kinase  KIF3B  Kinesin family member 3B  KIM-1  Kidney injury molecule 1  MAPK  Mitogen-activated protein kinase  MCP-1  Monocyte chemotactic protein-1  α-MSH  Alpha-melanocyte-stimulating hormone  MFG-E8  Milk fat globule-epidermal growth factor-factor VIII  MPT  Mitochondrial permeability transition  MSCs  Mesenchymal stem cells  NGAL  Neutrophil gelatinase-associated lipocalin  MDM2  Murine double minute-2  MMP-2  Matrix metallopeptidase 2  mTOR  Mammalian target of rapamycin  PI3K  Phosphatidylinositol-3 kinase  PACAP  Pituitary adenylate cyclase activating polypeptide  RAAS  Renin–angiotensin–aldosterone system  RANTES  Regulated upon activation normal T-cell expressed and secreted  RIP1  Receptor-interacting protein 1  TNF-α  Tumor necrosis factor-alpha  TWEAK  TNF-like weak inducer of apoptosis  VDRA  Vitamin D receptor agonist  Acute kidney injury  Kidney protection  Kidney repair  Renoprotection  Ischemia–reperfusion  Nephrotoxicity  
Steroid receptor RNA activator: Biologic function and role in disease 期刊论文
Clinica Chimica Acta, 2016, 卷号: 459, 页码: 137-146
作者:  Liu, Chan;  Wu, Hong-Tao;  Zhu, Neng;  Shi, Ya-Ning;  Liu, Zheng
收藏  |  浏览/下载:72/0  |  提交时间:2019/12/03
AF-2  activation function-2  AR  androgen receptor  C/EBPα  ccaat-enhancer-binding protein α  CTCF  CCCTC-binding factor  Ddx5  DEAD box protein 5  ERα  estrogen receptor α  GR  glucocorticoid receptor  Hes1  hairy and enhancer of split-1  HP1γ  heterochromatin protein 1γ  JNK  c-Jun N-terminal kinases  lncRNA  long noncoding RNA  MyoD  myogenic differentiation 1  NANOG  homeobox protein NANOG  NR  nuclear receptor(s)  p38 MAPK  mitogen-activated protein kinase  PACT  protein kinase RNA activator  PCOS  polycystic ovary syndrome  PKR  protein kinase RNA-dependent  PPARγ  Peroxisome Proliferator-Activated Receptor gamma  PR  progesterone receptor  PRC2  polycomb repressive complex 2  preTCRα  pre T-cell antigen receptor alpha  Pus1p  pseudouridine synthesis protein  RAR  retinoic acid receptor  RBP-J  recombination signal-binding protein J  RRM  RNA recognition motif  SF-1  steroidogenic factor 1  SHARP  retinoid and thyroid hormone receptors (SMRT)/HDAC1-associated repressor protein  SLIRP  stem-loop loop-interacting RNA RNA-binding protein  SRA  Steroid receptor RNA activator  SRAP  steroid receptor RNA activator protein  SRC-1  steroid receptor coactivator-1  STR  stem-loop structure  TNFα  tumor necrosis factor α  TRBP  transactivation response RNA-binding protein  TrxG  trithorax group  SRA  Long noncoding RNAs  Nuclear receptor  Transcriptional coactivator  
Steroid receptor RNA activator: Biologic function and role in disease 期刊论文
Clinica Chimica Acta, 2016, 卷号: 459, 页码: 137-146
作者:  Liu, Chan;  Wu, Hong-Tao;  Zhu, Neng;  Shi, Ya-Ning;  Liu, Zheng
收藏  |  浏览/下载:66/0  |  提交时间:2019/12/27
AF-2  activation function-2  AR  androgen receptor  C/EBPα  ccaat-enhancer-binding protein α  CTCF  CCCTC-binding factor  Ddx5  DEAD box protein 5  ERα  estrogen receptor α  GR  glucocorticoid receptor  Hes1  hairy and enhancer of split-1  HP1γ  heterochromatin protein 1γ  JNK  c-Jun N-terminal kinases  lncRNA  long noncoding RNA  MyoD  myogenic differentiation 1  NANOG  homeobox protein NANOG  NR  nuclear receptor(s)  p38 MAPK  mitogen-activated protein kinase  PACT  protein kinase RNA activator  PCOS  polycystic ovary syndrome  PKR  protein kinase RNA-dependent  PPARγ  Peroxisome Proliferator-Activated Receptor gamma  PR  progesterone receptor  PRC2  polycomb repressive complex 2  preTCRα  pre T-cell antigen receptor alpha  Pus1p  pseudouridine synthesis protein  RAR  retinoic acid receptor  RBP-J  recombination signal-binding protein J  RRM  RNA recognition motif  SF-1  steroidogenic factor 1  SHARP  retinoid and thyroid hormone receptors (SMRT)/HDAC1-associated repressor protein  SLIRP  stem-loop loop-interacting RNA RNA-binding protein  SRA  Steroid receptor RNA activator  SRAP  steroid receptor RNA activator protein  SRC-1  steroid receptor coactivator-1  STR  stem-loop structure  TNFα  tumor necrosis factor α  TRBP  transactivation response RNA-binding protein  TrxG  trithorax group  SRA  Long noncoding RNAs  Nuclear receptor  Transcriptional coactivator  
Steroid receptor RNA activator: Biologic function and role in disease 期刊论文
Clinica Chimica Acta, 2016, 卷号: 459, 页码: 137-146
作者:  Liu, Chan;  Wu, Hong-Tao;  Zhu, Neng;  Shi, Ya-Ning;  Liu, Zheng
收藏  |  浏览/下载:61/0  |  提交时间:2019/12/27
AF-2  activation function-2  AR  androgen receptor  C/EBPα  ccaat-enhancer-binding protein α  CTCF  CCCTC-binding factor  Ddx5  DEAD box protein 5  ERα  estrogen receptor α  GR  glucocorticoid receptor  Hes1  hairy and enhancer of split-1  HP1γ  heterochromatin protein 1γ  JNK  c-Jun N-terminal kinases  lncRNA  long noncoding RNA  MyoD  myogenic differentiation 1  NANOG  homeobox protein NANOG  NR  nuclear receptor(s)  p38 MAPK  mitogen-activated protein kinase  PACT  protein kinase RNA activator  PCOS  polycystic ovary syndrome  PKR  protein kinase RNA-dependent  PPARγ  Peroxisome Proliferator-Activated Receptor gamma  PR  progesterone receptor  PRC2  polycomb repressive complex 2  preTCRα  pre T-cell antigen receptor alpha  Pus1p  pseudouridine synthesis protein  RAR  retinoic acid receptor  RBP-J  recombination signal-binding protein J  RRM  RNA recognition motif  SF-1  steroidogenic factor 1  SHARP  retinoid and thyroid hormone receptors (SMRT)/HDAC1-associated repressor protein  SLIRP  stem-loop loop-interacting RNA RNA-binding protein  SRA  Steroid receptor RNA activator  SRAP  steroid receptor RNA activator protein  SRC-1  steroid receptor coactivator-1  STR  stem-loop structure  TNFα  tumor necrosis factor α  TRBP  transactivation response RNA-binding protein  TrxG  trithorax group  SRA  Long noncoding RNAs  Nuclear receptor  Transcriptional coactivator  
JIP1 Mediates Anterograde Transport of Rab10 Cargos during Neuronal Polarization 期刊论文
JOURNAL OF NEUROSCIENCE, 2014, 卷号: 34, 期号: 5, 页码: 1710-1723
Deng, CY; Lei, WL; Xu, XH; Ju, XC; Liu, Y; Luo, ZG
收藏  |  浏览/下载:28/0  |  提交时间:2014/07/30
Human Secreted Stabilin-1-Interacting Chitinase-like Protein Aggravates the Inflammation Associated With Rheumatoid Arthritis and Is a Potential Macrophage Inflammatory Regulator in Rodents 期刊论文
arthritis rheumatology, 2014
Xiao, Weichun; Meng, Geng; Zhao, Yanmei; Yuan, Huihui; Li, Tingting; Peng, Yanyan; Zhao, Yong; Luo, Ming; Zhao, Wenming; Li, Zhanguo; Zheng, Xiaofeng
收藏  |  浏览/下载:3/0  |  提交时间:2015/11/11
Transcriptome Profiling Analysis on Whole Bodies of Microbial Challenged Eriocheir sinensis Larvae for Immune Gene Identification and SNP Development 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 12, 页码: e82156
作者:  Cui, Zhaoxia;  Li, Xihong;  Liu, Yuan;  Song, Chengwen;  Hui, Min
收藏  |  浏览/下载:21/0  |  提交时间:2014/07/17


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