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期刊论文 [171]
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Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma
期刊论文
CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218
作者:
Chen, Zi-qi
;
Cao, Zhe-rui
;
Wang, Yi
;
Zhang, Xi
;
Xu, Lan
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/12/16
CYH33
MYC
P300
BET
B cell lymphoma
PI3K
W2476 represses TXNIP transcription via dephosphorylation of FOXO1 at Ser319
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2021, 页码: 11
作者:
Zhong, Li
;
Liu, Qing
;
Liu, Qiaofeng
;
Zhang, Shikai
;
Cao, Yongbing
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
chromatin immunoprecipitation
diabetes
transcription
TXNIP
W2476
SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Ren, Yu-ran
;
Ye, Yang-liang
;
Feng, Ying
;
Xu, Ti-fei
;
Shen, Yu
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
SL010110
gluconeogenesis
primary mouse hepatocytes
PEPCK1
acetylation
degradation
Design, synthesis, and biological evaluation of a new class of histone acetyltransferase p300 inhibitors (vol 180, pg 171, 2019)
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 186, 页码: 2
作者:
Liu, Ruiqi
;
Zhang, Zhuqing
;
Yang, Hong
;
Zhou, Kaixin
;
Geng, Meiyu
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
Design, synthesis, and biological evaluation of a new class of histone acetyltransferase p300 inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 171-190
作者:
Liu, Ruiqi
;
Zhang, Zhuqing
;
Yang, Hong
;
Zhou, Kaixin
;
Geng, Meiyu
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
p300 inhibitors
Epigenetics
Structure-activity relationship
Sensitive tumor cell proliferation
C646
Laminar shear stress alters endothelial KCa2.3 expression in H9c2 cells partially via regulating the PI3K/Akt/p300 axis
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2019, 卷号: 43, 期号: 3
作者:
Li, Guojian
;
Yang, Qionghui
;
Yang, Yong
;
Yang, Guokai
;
Wan, Jia
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/04
atrial fibrillation
laminar shear stress
Ca2+-activated K+ channel 2
3,phosphoinositide 3-kinase-protein kinase B-histone acetyltransferase p300
Functional Studies of Transcriptional Cofactors via Microinjection-Mediated Gene Editing in Xenopus.
期刊论文
Methods in molecular biology, 2019, 卷号: 1874, 页码: 507-524
作者:
Shibata Yuki
;
Bao Lingyu
;
Fu Liezhen
;
Shi Bingyin
;
Shi Yun-Bo
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/11/19
Histone modification
Xenopus tropicalis
Histone acetyltransferase
Xenopus laevis
Postembryonic development
Metamorphosis
CRISPR
Coactivator
Thyroid hormone receptor
Garcinol inhibits esophageal cancer metastasis by suppressing the p300 and TGF-β1 signaling pathways.
期刊论文
Acta pharmacologica Sinica, 2019
作者:
Wang Jing
;
Wu Man
;
Zheng Dan
;
Zhang Hong
;
Lv Yue
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Smad2/3
TGF-β1
esophageal cancer
garcinol
histone acetyltransferase
metastasis
p300/CBP
MicroRNA-377 exerts a potent suppressive role in osteosarcoma through the involvement of the histone acetyltransferase 1-mediated Wnt axis
期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 卷号: 234, 期号: 12
作者:
Li, Fang
;
Xia, Peng
;
Gu, Rui
;
Zhang, Wei
;
Shao, Liwei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
apoptosis
HAT1
microRNA-377
osteosarcoma
wnt signaling pathway
Cucurbit[8]uril-assisted peptide assembly for feasible electrochemical assay of histone acetyltransferase activity
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2019, 卷号: 411, 页码: 387-393
作者:
Miao, Xiangyang[1]
;
Wang, Yang[2]
;
Gu, Zhun[3]
;
Mao, Dongsheng[4]
;
Ning, Limin[5]
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/04/22
Histone acetyltransferase
p300
Cucurbit[8]uril
Peptide assembly
Peptide-templated silver nanoparticles
Electrochemical assay
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