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西安交通大学 [5]
上海药物研究所 [5]
武汉物理与数学研究所 [4]
复旦大学上海医学院 [4]
合肥物质科学研究院 [2]
兰州大学 [1]
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期刊论文 [23]
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Simulating androgen receptor selection in designer yeast
期刊论文
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2022, 卷号: 7
作者:
Zhang, Haoran
;
Zhang, Lu
;
Xu, Yipeng
;
Chen, Shaoyong
;
Ma, Zhenyi
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/12/23
Androgen receptor mutations
Androgen receptor antagonists
Prostate cancer
Saccharomyces cerevisiae
Enzalutamide-induced and PTH1R-mediated TGFBR2 degradation in osteoblasts confers resistance in prostate cancer bone metastases
期刊论文
CANCER LETTERS, 2022, 卷号: 525, 页码: 170-178
作者:
Su, Shang
;
Cao, Jingchen
;
Meng, Xiangqi
;
Liu, Ruihua
;
Vander Ark, Alexandra
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  |  
浏览/下载:49/0
  |  
提交时间:2022/01/04
Enzalutamide resistance
Prostate cancer
Bone microenvironment
TGFBR2
PTH1R
Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64
作者:
Fu, Weitao
;
Zhang, Minkui
;
Liao, Jianing
;
Tang, Qing
;
Lei, Yixuan
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  |  
浏览/下载:52/0
  |  
提交时间:2022/03/21
Design, synthesis and biological evaluation of novel thiohydantoin derivatives as potent androgen receptor antagonists for the treatment of prostate cancer
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 31, 页码: 13
作者:
Wang, Ao
;
Wang, Yawan
;
Meng, Xin
;
Yang, Yushe
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  |  
浏览/下载:14/0
  |  
提交时间:2021/05/24
Androgen receptor
Novel thiohydantoin derivatives
Androgen receptor antagonists
Prostate cancer
Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays
期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 16, 期号: 6, 页码: 416-427
作者:
Hou, Tingjun
;
Li, Dan
;
Chang, Shan
;
Xu, Lei
;
Sun, Huiyong
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  |  
浏览/下载:260/0
  |  
提交时间:2019/06/24
Androgen receptor
AR ligand
Virtual screening
AR agonist
AR antagonist
Communication between the Ligand-Binding Pocket and the Activation Function-2 Domain of Androgen Receptor Revealed by Molecular Dynamics Simulations
期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2019, 卷号: 59, 期号: 2, 页码: 842-857
作者:
Hou, Tingjun
;
Li, Youyong
;
Yu, Huidong
;
Li, Dan
;
Liu, Hui
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2019/06/24
Rational drug design for androgen receptor and glucocorticoids receptor dual antagonist
期刊论文
2019, 卷号: 166, 页码: 232-242
作者:
Wu, Meng
;
Xie, Yongli
;
Cui, Xiangling
;
Huang, Chenchao
;
Zhang, Rongyu
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/01/03
Prostate cancer
Enzalutamide resistance
Antagonist
Androgen receptor
Glucocorticoids receptor
Synthesis of androgen receptor antagonists containing a pentafluorosulfanyl (SF5) moiety
期刊论文
ARCHIV DER PHARMAZIE, 2018, 卷号: 351, 期号: 11
作者:
Jin, Jiyu
;
Zhou, Yan
;
Yang, Dehua
;
Zhang, Qiumeng
;
Wang, Ming-Wei
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  |  
浏览/下载:69/0
  |  
提交时间:2019/01/08
androgen receptor
antagonist
enzalutamide
pentafluorosulfanyl
Molecular Dynamics Simulations Revealed the Regulation of Ligands to the Interactions between Androgen Receptor and Its Coactivator
期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2018, 卷号: 58, 期号: 8, 页码: 1652-1661
作者:
Liu, Na
;
Zhou, Wenfang
;
Guo, Yue
;
Wang, Junmei
;
Fu, Weitao
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2018/11/05
Quantitative Study of Impurities in Enzalutamide and Identification, Isolation, Characterization of Its Four Degradation Products Using HPLC, Semi-preparative LC, LC/ESI-MS and NMR Analyses
期刊论文
CHROMATOGRAPHIA, 2018, 卷号: 81, 期号: 11
作者:
Zhou, Ainan
;
Ruan, Lejun
;
Duan, Gengli
;
Li, Jianqi
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/05
Enzalutamide
Impurities
Degradation
Prep-HPLC
LC-MS
NMR
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