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Synthesis and pharmacological evaluation of choroquine derivatives bearing long aminated side chains as antivirus and anti-inflammatory agents
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 8
作者:
Song, Zilan
;
Liu, Yuting
;
Xie, Chenghu
;
Tong, Xiankun
;
Wang, Xue
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/11/04
Choroquine
Aminochloroquine
Antivirus
Anti-inflammatory
Cytokines
Picomolar antimalarial agent from a Chinese medicinal plant
期刊论文
SCIENCE CHINA-CHEMISTRY, 2021, 页码: 5
作者:
Zhou, Bin
;
Zimbres, Flavia M.
;
Butler, Joshua H.
;
Xu, Cheng-Hui
;
Haney, Reagan S.
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  |  
浏览/下载:62/0
  |  
提交时间:2021/12/01
medicinal plants
dimeric sesquiterpenoids
antimalarial agent
structure-activity relationship
Hydroxychloroquine Increased Anxiety-Like Behaviors and Disrupted the Expression of Some Related Genes in the Mouse Brain
期刊论文
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12, 页码: 10
作者:
Xu, Hang
;
Zhang, Xiang Yang
;
Wang, Wei Wen
;
Wang, Jiesi
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  |  
浏览/下载:55/0
  |  
提交时间:2021/06/09
hydroxychloroquine
anxiety
BDNF
IL-1β
CRH
SLC6a4
AIF1
In Vivo Efficacy and Metabolism of the Antimalarial Cycleanine and Improved In Vitro Antiplasmodial Activity of Semisynthetic Analogues
期刊论文
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 卷号: 65, 期号: 2, 页码: 11
作者:
Uche, Fidelia Ijeoma
;
Guo, Xiaozhen
;
Okokon, Jude
;
Ullah, Imran
;
Horrocks, Paul
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  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
malaria
Plasmodium falciparum
Plasmodium berghei
bisbenzylisoquinoline alkaloids
cycleanine
metabolism
in vivo activity
antimalarial agents
drug metabolism
Therapeutic drugs for SARS-CoV-2 treatment: Current state and perspective
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 90, 页码: 19
作者:
Bolarin, Joshua Adedeji
;
Oluwatoyosi, Mercy Adaramodu
;
Orege, Joshua Iseoluwa
;
Ayeni, Emmanuel Ayodeji
;
Ibrahim, Yusuf Ajibola
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  |  
浏览/下载:35/0
  |  
提交时间:2021/03/29
COVID-19
Therapeutics
Drug interaction
Antiviral drugs
Health and safety
Non-thermal plasma induces apoptosis accompanied by protective autophagy via activating JNK/Sestrin2 pathway
期刊论文
JOURNAL OF PHYSICS D-APPLIED PHYSICS, 2020, 卷号: 53
作者:
Ma, Jie
;
Yu, K. N.
;
Zhang, Hao
;
Nie, Lili
;
Cheng, Cheng
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  |  
浏览/下载:94/0
  |  
提交时间:2020/10/28
non-thermal plasma
apoptosis
protective autophagy
c-JUN N-terminal kinase
Sestrin2
Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 44, 页码: 27381-27387
作者:
Li, Zhe
;
Li, Xin
;
Huang, Yi-You
;
Wu, Yaoxing
;
Liu, Runduo
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  |  
浏览/下载:73/0
  |  
提交时间:2020/12/24
virtual screening
SARS-CoV-2
drug repurposing
free energy perturbation
main protease
Imidazole-fused benzothiadiazole-based red-emissive fluorescence probe for lysosomal pH imaging in living cells
期刊论文
TALANTA, 2020, 卷号: 217, 页码: 10
作者:
Li, Lingling
;
Li, Yang
;
Dang, Yijing
;
Chen, Tingting
;
Zhang, Ao
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2020/12/24
Imidazole-fused benzothiadiazole
pH imaging
Lysosome
Fluorescence probe
Overview of therapeutic drug research for COVID-19 in China
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Li, Heng
;
Yang, Li
;
Liu, Fei-fei
;
Ma, Xin-na
;
He, Pei-lan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/12/24
SARS-CoV-2
COVID-19
novel coronavirus pneumonia
therapeutic drugs
anti-SARS-CoV-2 agents
favipiravir
hydroxychloroquine
traditional Chinese medicine
Low dose of hydroxychloroquine reduces fatality of critically ill patients with COVID-19
期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2020, 页码: 7
作者:
Yu Bo
;
Li Chenze
;
Chen Peng
;
Zhou Ning
;
Wang Luyun
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  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
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