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Discovery of 1,5-Dihydro-4H-imidazol-4-one Derivatives as Potent, Selective Antagonists of CXC Chemokine Receptor 2
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 5, 页码: 836-845
作者:
Che, Jinxin
;
Wang, Zhilong
;
Shen, Zheyuan
;
Zhuang, Weihao
;
Ying, Huazhou
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/08/17
cancer metastasis
CXCR1
CXCR2
selectivity
antagonist
1,5-dihydro-4H-imidazol-4-one
Mechanism of Cxc Chemokine Ligand 5 (CXCL5)/Cxc Chemokine Receptor 2 (CXCR2) Bio-Axis in Mice with Acute Respiratory Distress Syndrome
期刊论文
MEDICAL SCIENCE MONITOR, 2019, 卷号: 25
作者:
Wang, Chang-yong
;
Shang, Min
;
Zhou, Chen-liang
;
Feng, Li-zhi
;
Zhou, Qing-shan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
Chemokine CXCL5
Inflammation
Respiratory Distress Syndrome, Adult
Ligand-based pharmacophore model for the discovery of novel CXCR2 antagonists as anti-cancer metastatic agents
期刊论文
ROYAL SOCIETY OPEN SCIENCE, 2018, 卷号: 5, 期号: 7
作者:
Che, Jinxin
;
Wang, Zhilong
;
Sheng, Haichao
;
Huang, Feng
;
Dong, Xiaowu
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
pharmacophore model
CXCR2
antagonists
anti-cancer metastasis
The chemical diversity and structure-based evolution of non-peptide CXCR4 antagonists with diverse therapeutic potential
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 149, 页码: 148-169
作者:
Peng, Dian
;
Cao, Bin
;
Zhou, Ying-Jun
;
Long, Ya-Qiu
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
CXC chemokine receptor 4
Small molecule antagonists
Structure-based optimization
HIV-1 entry
Tumor metastasis
Inflammation
Ischemia-reperfusion
Autoimmune
MicroRNA-381 Favors Repair of Nerve Injury Through Regulation of the SDF-1/CXCR4 Signaling Pathway via LRRC4 in Acute Cerebral Ischemia after Cerebral Lymphatic Blockage
期刊论文
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018, 卷号: 46, 期号: 3
作者:
Piao, Jian-Min
;
Wu, Wei
;
Yang, Zhong-Xi
;
Li, Yu-Zhen
;
Luo, Qi
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
MicroRNA-381
Leucine-rich repeat C4 protein
Stromal cell-derived factor-1/CXC chemokine receptor-4 signaling pathway
Cerebral lymphatic blockage
Acute cerebral ischemia
Repair of nerve injury
Extracellular matrix protein 1 promotes follicular helper T cell differentiation and antibody production
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 34, 页码: 8621-8626
作者:
He, Lan
;
Gu, Wangpeng
;
Zhang, Yuan
;
Yan, Chenghua
;
Su, Pan
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  |  
浏览/下载:69/0
  |  
提交时间:2019/04/28
Cxc Chemokine Receptor-5
Icos
Bcl6
Induction
Responses
Stat5
Pd-1
Fh
Bicyclo[2.2.1]heptane containing N,N-diarylsquaramide CXCR2 selective antagonists as anti-cancer metastasis agents
期刊论文
RSC ADVANCES, 2018, 卷号: 8, 期号: 20, 页码: 11061-11069
作者:
Che, Jin-Xin
;
Wang, Zhi-Long
;
Dong, Xiao-Wu
;
Hu, You-Hong
;
Xie, Xin
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Molecular cloning, biological effect, and tissue distribution of interleukin-8 protein in mandarin fish (Siniperca chuasti) upon Flavobacterium columnare infection
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 66, 期号: 1, 页码: 112-119
作者:
Wang, Gai Ling
;
Wang, Ming Cheng
;
Zhang, Xiao Wen
;
Chang, Ming Xian
;
Xie, Hai Xia
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/09/19
Interleuldn-8
Biological effect
Tissue distribution
Mandarin fish (Siniperca chuatsi)
Elevating CXCR7 Improves Angiogenic Function of EPCs via Akt/GSK-3 beta/Fyn-Mediated Nrf2 Activation in Diabetic Limb Ischemia
期刊论文
CIRCULATION RESEARCH, 2017, 卷号: 120, 期号: 5
作者:
Dai, Xiaozhen
;
Yan, Xiaoqing
;
Zeng, Jun
;
Chen, Jing
;
Wang, Yuehui
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
angiogenesis
chemokine CXCL12
CXC chemokine receptor type 7
endothelial progenitor cells
hindlimb ischemia
Overexpression of CXCR4 promotes invasion and migration of non-small cell lung cancer via EGFR and MMP-9
期刊论文
ONCOLOGY LETTERS, 2017, 卷号: 14, 期号: 6
作者:
Zuo, Jianhong
;
Wen, Meiling
;
Li, Sai
;
Lv, Xiu
;
Wang, Lei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
CXC receptor 4
epidermal growth factor receptor
matrix metallopeptidase 9
non-small cell lung cancer
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