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科研机构
上海药物研究所 [19]
内容类型
期刊论文 [19]
发表日期
2020 [19]
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共19条,第1-10条
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发表日期:2020
专题:上海药物研究所
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A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280
作者:
Wang, Zhen
;
Zhang, Hao
;
Chen, Baoen
;
Ouyang, Sisheng
;
Zheng, Tong
收藏
  |  
浏览/下载:124/0
  |  
提交时间:2021/05/24
SPOP
Protein‐
protein interaction
Clear cell Renal Cell Carcinomas
Crystal structure
Peptide inhibitor
Proanthocyanidin Block Arrays (PACBAR) for Comprehensive Capture and Delineation of Proanthocyanidin Structures
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020, 卷号: 68, 期号: 47, 页码: 13541-13549
作者:
Jing, Shuxi
;
Zeller, Wayne E.
;
Ferreira, Daneel
;
Zhou, Bin
;
Nam, Joo-Won
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2021/05/24
proanthocyanidins
polyphenols
nomenclature
structure-activity relationships
Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 5
作者:
Zhang, Bin
;
Liao, Liping
;
Wu, Fan
;
Zhang, Fengcai
;
Sun, Zhongya
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/05/24
SMYD2 inhibitors
Thermal shift assay
Structure-activity relationships
Resistance to Some But Not Other Dimeric Lindenane Sesquiterpenoid Esters Is Mediated by Mutations in a Plasmodium falciparum Esterase
期刊论文
ACS INFECTIOUS DISEASES, 2020, 卷号: 6, 期号: 11, 页码: 2994-3003
作者:
Butler, Joshua H.
;
Baptista, Rodrigo P.
;
Valenciano, Ana L.
;
Zhou, Bin
;
Kissinger, Jessica C.
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/05/24
Plasmodium
PfPARE
structure-resistance relationship study
Malaria Box
Pathogen Box
lindenane sesquiterpenoid dimers
Chemical Constituents from Citrus changshan-huyou and Their Anti-Inflammatory Activities
期刊论文
CHEMISTRY & BIODIVERSITY, 2020, 页码: 10
作者:
Hu, Yu-Hong
;
Liu, Jin
;
Li, Heng
;
Tang, Wei
;
Li, Xu-Wen
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/12/21
Citrus changshan-huyou
limonoids
structure modification
anti-inflammation
The impact of structural modification of sulfated polysaccharides on bone morphogenic protein 2 and inhibition of endothelial cell angiogenesis
期刊论文
CARBOHYDRATE RESEARCH, 2020, 卷号: 496, 页码: 10
作者:
Wang, Ying
;
Xiao, Fei
;
Jin, Can
;
Wang, Wucheng
;
Chen, Xia
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/12/21
Sulfated polysaccharides
Bone morphogenic protein 2
Structure and activity relationship
Angiogenesis
Two new flavonoid glycosides isolated from the fruits of Catalpa ovata
期刊论文
PHARMACOGNOSY MAGAZINE, 2020, 卷号: 16, 期号: 72, 页码: 812-816
作者:
Zhang, Liu-Qiang
;
Xue, Hai-Bing
;
Zhu, Wei-Liang
;
Li, Yi-Ming
;
Chen, Kai-Xian
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2021/05/24
Antioxidant activity
Catalpa ovata
flavonoid glycosides
polyphenols
structure–
activity relationship
Chemical structure elucidation of an inulin-type fructan isolated from Lobelia chinensis lour with anti-obesity activity on diet-induced mice
期刊论文
CARBOHYDRATE POLYMERS, 2020, 卷号: 240, 页码: 8
作者:
Zhang, Xue
;
Hu, Pei
;
Zhang, Xiaorui
;
Li, Xiaojun
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/12/24
Lobelia chinensis Lour polysaccharides
anti-obesity
chemical structure
inulin-type fructan
high fat diet-induced mice
Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 28, 页码: 9313-9325
作者:
Chang, Rulue
;
Zhang, Xin
;
Qiao, Anna
;
Dai, Antao
;
Belousoff, Matthew J.
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2020/12/24
glucagon receptor
glucagon-like peptide-1 receptor
dual agonist
cryo-electron microscopy
single particle analysis
structure-function
structural biology
peptide 15 (P15)
metabolic disorder
G protein?coupled receptor (GPCR)
glucagon
GLP-1 receptor
Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5
作者:
Satheeshkumar, Rajendran
;
Zhu, Rui
;
Feng, Bo
;
Huang, Chao
;
Gao, Ya
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Heterocyclic bis-aryl amides
PTP1B
SHP2
Inhibitors
Structure-activity relationships (SAR)
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